D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major
D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences
J. Mol. Biol., 435 (2023)

HOX antisense intergenic RNA myeloid 1 conserved region 1   (Rfam: RF01975)

Seed sequences
All NCMs (CSV file) (all) positive sequences (all) negative sequences (random) (training) positive sequences (training) negative sequences (testing) positive sequences (testing) negative sequences 

Options
Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN
Rfam
D-ORB
Augmented
(GUYUN)
(UUNA)
(.NGCR.)
G(C(A))
((Y)CC)C
C(A(C))
100.0
100.0
92.9
100.0
92.9
100.0
(GUYUN)
(.NGCR.)
(.NGCR.)
G(C(A))
C(A(C))

% of positive sequence with ORB





Deep neural network:

5-fold cross-validation: 99.9 %
(± 0.0732 %)
Decision tree:

5-fold cross-validation: 95.6 %
(± 6.46 %)
D-ORB structure
D-ORB structure decision tree:

5-fold cross-validation: 95.6 %
(± 6.74 %)
of AAFC03094354.1/97532-97659
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
(.((.....)).)(.((....)))((((((((((((((.(((((((((((...))))))..)((((((((((((((((((((((....))))))))))))))))))))))))))))))))))))))))
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678

abstract shape: ()()(()())

Number of sequences
Structure ORBs (out of 14) (%)
1 (GUYUN)
 14 100.0
>AAWR02014100.1/90879-91003
CACCGUUUCAGUGGCAUUUAAAUCCCGGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCAGCUGCGGUGGCUGCAAGGGCAGAUUCAGAGCGCUGGG
...(.....)...................................................................................................................
>AC116662.1/86579-86455
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUGUAGGUGACGCGCGCUCGCCCCCCCAGGCAGCCCGGGCCGCGGCGGUAGCUACGGCCGCUGCCGGAGCUGACUUGGAGCAUUGGG
...(.....)...................................................................................................................
>AANU01289429.1/101-4
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCUGCGGCGA
...(.....)........................................................................................
>AC004079.1/78519-78643
CACCGUUUUAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUAGGCGGCGGCAGCUGCUGCGGCGACUGCAAAGGCCGAUUUGGAGUGCUGGA
...(.....)...................................................................................................................
>AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...(.....)......................................................................................................................
>ABRT010305835.1/90-212
CACCAUUUCAGUGGCAUUUAAAUCCCCGGCGCUUCUCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAACCCAAGAGGCGGCAGCAGCUGCGGCGGCUGCCACGGCAGAUUCGGUGCUGGG
.....................................(.....)...............................................................................
>AAQQ01071855.1/104-228
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCUGUCUAGGUGACGCGCAGCAGCCCCCCCAGGCAGCCCAGGCGACGGCAGCAGCUGCAGCGGCUGCAACGACAGAUUCCGAGCGCUGGG
...(.....)...................................................................................................................
>ABRO01036369.1/72-199
CACUGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUGGGUGACGUGCCGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCAGCUGCGGCGGCUGCAAAGGCAGAUUCAGAGCGCUGGA
...(.....)......................................................................................................................
>AAGV020346967.1/2189-2313
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCGUCUGGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCCGCAGCAGCGGCGGUGGCAGCAACCGCCCAUUCGGAGCACUGGG
...(.....)...................................................................................................................
>ABRP01099855.1/207-331
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGACGGCGGCAGCUGCGACGGCUGCAAGGACAGAUUCGCAGCGCUGGG
...(.....)...................................................................................................................
>AAYZ01055278.1/10927-11050
CACCGUUUCAGUGGCAUUUAAGUCCCGGCGCUCCUCGGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGAGGCGGCAGAAGCUGCGGUGGCUGCCAACGCAGCUUCACAGCUCUGGG
...(.....)..................................................................................................................
>AAGW02035950.1/13970-13846
CACCGUUUCAGUGGCAUUUAAGUCCCCGGCGCUCCUCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCUCAGGAGGCGGCAGAAGCUGCGGCGGCUGCAACUGCAGCUUCACAGCCCUGGG
...(.....)...................................................................................................................
>AAKN02039089.1/5983-6107
CACCGUUUCAGUGGCAUUUAAAUCCCUGGCGCUCCUCCGCCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCAGCGGCAGCAGCUGCGGCGCCUGCCACGGCAGAUUCGGAGCGCUGGG
...(.....)...................................................................................................................
>AANG01383093.1/6089-6214
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGCGGCGGCAGCUGCUGCGGCGGCUGCAAGGGCAGAUUCGGAGCGCUGGG
...(.....)....................................................................................................................
2 (GUYUN)
(UUNA)
 13 92.9
>AANU01289429.1/101-4
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCUGCGGCGA
...(.....)......(....)............................................................................
>AAGV020346967.1/2189-2313
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCGUCUGGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCCGCAGCAGCGGCGGUGGCAGCAACCGCCCAUUCGGAGCACUGGG
...(.....)......(....).......................................................................................................
>ABRO01036369.1/72-199
CACUGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUGGGUGACGUGCCGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCAGCUGCGGCGGCUGCAAAGGCAGAUUCAGAGCGCUGGA
...(.....)......(....)..........................................................................................................
>AAQQ01071855.1/104-228
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCUGUCUAGGUGACGCGCAGCAGCCCCCCCAGGCAGCCCAGGCGACGGCAGCAGCUGCAGCGGCUGCAACGACAGAUUCCGAGCGCUGGG
...(.....)......(....).......................................................................................................
>AAYZ01055278.1/10927-11050
CACCGUUUCAGUGGCAUUUAAGUCCCGGCGCUCCUCGGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGAGGCGGCAGAAGCUGCGGUGGCUGCCAACGCAGCUUCACAGCUCUGGG
...(.....)......(....)......................................................................................................
>AAGW02035950.1/13970-13846
CACCGUUUCAGUGGCAUUUAAGUCCCCGGCGCUCCUCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCUCAGGAGGCGGCAGAAGCUGCGGCGGCUGCAACUGCAGCUUCACAGCCCUGGG
...(.....)......(....).......................................................................................................
>AC004079.1/78519-78643
CACCGUUUUAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUAGGCGGCGGCAGCUGCUGCGGCGACUGCAAAGGCCGAUUUGGAGUGCUGGA
...(.....)......(....).......................................................................................................
>AAKN02039089.1/5983-6107
CACCGUUUCAGUGGCAUUUAAAUCCCUGGCGCUCCUCCGCCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCAGCGGCAGCAGCUGCGGCGCCUGCCACGGCAGAUUCGGAGCGCUGGG
...(.....)......(....).......................................................................................................
>AANG01383093.1/6089-6214
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGCGGCGGCAGCUGCUGCGGCGGCUGCAAGGGCAGAUUCGGAGCGCUGGG
...(.....)......(....)........................................................................................................
>AC116662.1/86579-86455
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUGUAGGUGACGCGCGCUCGCCCCCCCAGGCAGCCCGGGCCGCGGCGGUAGCUACGGCCGCUGCCGGAGCUGACUUGGAGCAUUGGG
...(.....)......(....).......................................................................................................
>AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...(.....)......(....)..........................................................................................................
>AAWR02014100.1/90879-91003
CACCGUUUCAGUGGCAUUUAAAUCCCGGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCAGCUGCGGUGGCUGCAAGGGCAGAUUCAGAGCGCUGGG
...(.....)......(....).......................................................................................................
>ABRP01099855.1/207-331
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGACGGCGGCAGCUGCGACGGCUGCAAGGACAGAUUCGCAGCGCUGGG
...(.....)......(....).......................................................................................................
3 (GUYUN)
(UUNA)
(.NGCR.)
 11 78.6
>AANG01383093.1/6089-6214
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGCGGCGGCAGCUGCUGCGGCGGCUGCAAGGGCAGAUUCGGAGCGCUGGG
...(.....)......(....)...........................................................(....).......................................
>ABRO01036369.1/72-199
CACUGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUGGGUGACGUGCCGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCAGCUGCGGCGGCUGCAAAGGCAGAUUCAGAGCGCUGGA
...(.....)......(....)................................................................(....)....................................
>AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...(.....)......(....).............................................................(....).......................................
>ABRP01099855.1/207-331
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGACGGCGGCAGCUGCGACGGCUGCAAGGACAGAUUCGCAGCGCUGGG
...(.....)......(....).............................................................(....)....................................
>AANU01289429.1/101-4
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCUGCGGCGA
...(.....)......(....)..........................................................(....)............
>AAWR02014100.1/90879-91003
CACCGUUUCAGUGGCAUUUAAAUCCCGGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCAGCUGCGGUGGCUGCAAGGGCAGAUUCAGAGCGCUGGG
...(.....)......(....).............................................................(....)....................................
>AC004079.1/78519-78643
CACCGUUUUAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUAGGCGGCGGCAGCUGCUGCGGCGACUGCAAAGGCCGAUUUGGAGUGCUGGA
...(.....)......(....)..........................................................(....).......................................
>AAQQ01071855.1/104-228
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCUGUCUAGGUGACGCGCAGCAGCCCCCCCAGGCAGCCCAGGCGACGGCAGCAGCUGCAGCGGCUGCAACGACAGAUUCCGAGCGCUGGG
...(.....)......(....).............................................................(....)....................................
>AAGW02035950.1/13970-13846
CACCGUUUCAGUGGCAUUUAAGUCCCCGGCGCUCCUCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCUCAGGAGGCGGCAGAAGCUGCGGCGGCUGCAACUGCAGCUUCACAGCCCUGGG
...(.....)......(....)......................................................................(....)...........................
>AAGV020346967.1/2189-2313
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCGUCUGGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCCGCAGCAGCGGCGGUGGCAGCAACCGCCCAUUCGGAGCACUGGG
...(.....)......(....).............................................................(....)....................................
>AAKN02039089.1/5983-6107
CACCGUUUCAGUGGCAUUUAAAUCCCUGGCGCUCCUCCGCCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCAGCGGCAGCAGCUGCGGCGCCUGCCACGGCAGAUUCGGAGCGCUGGG
...(.....)......(....).............................................................(....)....................................
4 (GUYUN)
(UUNA)
(.NGCR.)
G(C(A))
 10 71.4
>AANU01289429.1/101-4
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCUGCGGCGA
...(.....)...(.((....)))........................................................(....)............
>AAKN02039089.1/5983-6107
CACCGUUUCAGUGGCAUUUAAAUCCCUGGCGCUCCUCCGCCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCAGCGGCAGCAGCUGCGGCGCCUGCCACGGCAGAUUCGGAGCGCUGGG
...(.....)...(.((....)))...........................................................(....)....................................
>AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...(.....)...(.((....)))...........................................................(....).......................................
>ABRP01099855.1/207-331
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGACGGCGGCAGCUGCGACGGCUGCAAGGACAGAUUCGCAGCGCUGGG
...(.....)...(.((....)))...........................................................(....)....................................
>AAQQ01071855.1/104-228
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCUGUCUAGGUGACGCGCAGCAGCCCCCCCAGGCAGCCCAGGCGACGGCAGCAGCUGCAGCGGCUGCAACGACAGAUUCCGAGCGCUGGG
...(.....)...(.((....)))...........................................................(....)....................................
>AANG01383093.1/6089-6214
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGCGGCGGCAGCUGCUGCGGCGGCUGCAAGGGCAGAUUCGGAGCGCUGGG
...(.....)...(.((....))).........................................................(....).......................................
>AC004079.1/78519-78643
CACCGUUUUAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUAGGCGGCGGCAGCUGCUGCGGCGACUGCAAAGGCCGAUUUGGAGUGCUGGA
...(.....)...(.((....)))........................................................(....).......................................
>AAWR02014100.1/90879-91003
CACCGUUUCAGUGGCAUUUAAAUCCCGGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCAGCUGCGGUGGCUGCAAGGGCAGAUUCAGAGCGCUGGG
...(.....)...(.((....)))...........................................................(....)....................................
>AAGV020346967.1/2189-2313
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCGUCUGGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCCGCAGCAGCGGCGGUGGCAGCAACCGCCCAUUCGGAGCACUGGG
...(.....)...(.((....)))...........................................................(....)....................................
>ABRO01036369.1/72-199
CACUGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUGGGUGACGUGCCGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCAGCUGCGGCGGCUGCAAAGGCAGAUUCAGAGCGCUGGA
...(.....)...(.((....))..)............................................................(....)....................................
5 (GUYUN)
(UUNA)
(.NGCR.)
G(C(A))
((Y)CC)C
 8 57.1
>AAWR02014100.1/90879-91003
CACCGUUUCAGUGGCAUUUAAAUCCCGGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCAGCUGCGGUGGCUGCAAGGGCAGAUUCAGAGCGCUGGG
...(.....)...(.((....)))...................((.............)..).....................(....)....................................
>ABRP01099855.1/207-331
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGACGGCGGCAGCUGCGACGGCUGCAAGGACAGAUUCGCAGCGCUGGG
...(.....)...(.((....)))...................((.............)..).....................(....)....................................
>ABRO01036369.1/72-199
CACUGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUGGGUGACGUGCCGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCAGCUGCGGCGGCUGCAAAGGCAGAUUCAGAGCGCUGGA
...(.....)...(.((....))..)................((...............)..).......................(....)....................................
>AAQQ01071855.1/104-228
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCUGUCUAGGUGACGCGCAGCAGCCCCCCCAGGCAGCCCAGGCGACGGCAGCAGCUGCAGCGGCUGCAACGACAGAUUCCGAGCGCUGGG
...(.....)...(.((....)))....................((.............)..)....................(....)....................................
>AANU01289429.1/101-4
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCUGCGGCGA
...(.....)...(.((....)))......................(..(........)..)..................(....)............
>AAKN02039089.1/5983-6107
CACCGUUUCAGUGGCAUUUAAAUCCCUGGCGCUCCUCCGCCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCAGCGGCAGCAGCUGCGGCGCCUGCCACGGCAGAUUCGGAGCGCUGGG
...(.....)...(.((....)))...................((.............)..).....................(....)....................................
>AANG01383093.1/6089-6214
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGCGGCGGCAGCUGCUGCGGCGGCUGCAAGGGCAGAUUCGGAGCGCUGGG
...(.....)...(.((....)))....................((.............)..)..................(....).......................................
>AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...(.....)...(.((....)))...................((.............)..).....................(....).......................................
6 (GUYUN)
(UUNA)
(.NGCR.)
G(C(A))
((Y)CC)C
C(A(C))
 6 42.9
>AANG01383093.1/6089-6214
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGCGGCGGCAGCUGCUGCGGCGGCUGCAAGGGCAGAUUCGGAGCGCUGGG
(.((.....)).)(.((....)))....................((.............)..)..................(....).......................................
>AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
(.((.....)).)(.((....)))...................((.............)..).....................(....).......................................
>ABRP01099855.1/207-331
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGACGGCGGCAGCUGCGACGGCUGCAAGGACAGAUUCGCAGCGCUGGG
(.((.....)).)(.((....)))...................((.............)..).....................(....)....................................
>AAWR02014100.1/90879-91003
CACCGUUUCAGUGGCAUUUAAAUCCCGGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCAGCUGCGGUGGCUGCAAGGGCAGAUUCAGAGCGCUGGG
(.((.....)).)(.((....)))...................((.............)..).....................(....)....................................
>AAQQ01071855.1/104-228
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCUGUCUAGGUGACGCGCAGCAGCCCCCCCAGGCAGCCCAGGCGACGGCAGCAGCUGCAGCGGCUGCAACGACAGAUUCCGAGCGCUGGG
(.((.....)).)(.((....)))....................((.............)..)....................(....)....................................
>AAKN02039089.1/5983-6107
CACCGUUUCAGUGGCAUUUAAAUCCCUGGCGCUCCUCCGCCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCAGCGGCAGCAGCUGCGGCGCCUGCCACGGCAGAUUCGGAGCGCUGGG
(.((.....)).)(.((....)))...................((.............)..).....................(....)....................................

>AAWR02014100.1/90879-91003
CACCGUUUCAGUGGCAUUUAAAUCCCGGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCAGCUGCGGUGGCUGCAAGGGCAGAUUCAGAGCGCUGGG
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
...(.....)......(....).............................................................(....)....................................
...(.....)...(.((....)))...........................................................(....)....................................
...(.....)...(.((....)))...................((.............)..).....................(....)....................................
(.((.....)).)(.((....)))...................((.............)..).....................(....)....................................
>AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...(.....)......................................................................................................................
...(.....)......(....)..........................................................................................................
...(.....)......(....).............................................................(....).......................................
...(.....)...(.((....)))...........................................................(....).......................................
...(.....)...(.((....)))...................((.............)..).....................(....).......................................
(.((.....)).)(.((....)))...................((.............)..).....................(....).......................................
>AAQQ01071855.1/104-228
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCUGUCUAGGUGACGCGCAGCAGCCCCCCCAGGCAGCCCAGGCGACGGCAGCAGCUGCAGCGGCUGCAACGACAGAUUCCGAGCGCUGGG
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
...(.....)......(....).............................................................(....)....................................
...(.....)...(.((....)))...........................................................(....)....................................
...(.....)...(.((....)))....................((.............)..)....................(....)....................................
(.((.....)).)(.((....)))....................((.............)..)....................(....)....................................
>ABRP01099855.1/207-331
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGACGGCGGCAGCUGCGACGGCUGCAAGGACAGAUUCGCAGCGCUGGG
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
...(.....)......(....).............................................................(....)....................................
...(.....)...(.((....)))...........................................................(....)....................................
...(.....)...(.((....)))...................((.............)..).....................(....)....................................
(.((.....)).)(.((....)))...................((.............)..).....................(....)....................................
>AAKN02039089.1/5983-6107
CACCGUUUCAGUGGCAUUUAAAUCCCUGGCGCUCCUCCGCCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCAGCGGCAGCAGCUGCGGCGCCUGCCACGGCAGAUUCGGAGCGCUGGG
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
...(.....)......(....).............................................................(....)....................................
...(.....)...(.((....)))...........................................................(....)....................................
...(.....)...(.((....)))...................((.............)..).....................(....)....................................
(.((.....)).)(.((....)))...................((.............)..).....................(....)....................................
>AANG01383093.1/6089-6214
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGCGGCGGCAGCUGCUGCGGCGGCUGCAAGGGCAGAUUCGGAGCGCUGGG
...(.....)....................................................................................................................
...(.....)......(....)........................................................................................................
...(.....)......(....)...........................................................(....).......................................
...(.....)...(.((....))).........................................................(....).......................................
...(.....)...(.((....)))....................((.............)..)..................(....).......................................
(.((.....)).)(.((....)))....................((.............)..)..................(....).......................................
>AANU01289429.1/101-4
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCUGCGGCGA
...(.....)........................................................................................
...(.....)......(....)............................................................................
...(.....)......(....)..........................................................(....)............
...(.....)...(.((....)))........................................................(....)............
...(.....)...(.((....)))......................(..(........)..)..................(....)............
>ABRO01036369.1/72-199
CACUGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUGGGUGACGUGCCGUCGCCCCCCCAGGCAGCCCAGGCGGCGGCAGCUGCAGCUGCGGCGGCUGCAAAGGCAGAUUCAGAGCGCUGGA
...(.....)......................................................................................................................
...(.....)......(....)..........................................................................................................
...(.....)......(....)................................................................(....)....................................
...(.....)...(.((....))..)............................................................(....)....................................
...(.....)...(.((....))..)................((...............)..).......................(....)....................................
>AC004079.1/78519-78643
CACCGUUUUAGUGGCAUUUAAAUCCCCGGCGCUCCGCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUAGGCGGCGGCAGCUGCUGCGGCGACUGCAAAGGCCGAUUUGGAGUGCUGGA
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
...(.....)......(....)..........................................................(....).......................................
...(.....)...(.((....)))........................................................(....).......................................
>AAGV020346967.1/2189-2313
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCCGUCUGGGUGACGCGCAGUCGCCCCCCCAGGCAGCCCAGGCGGCCGCAGCAGCGGCGGUGGCAGCAACCGCCCAUUCGGAGCACUGGG
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
...(.....)......(....).............................................................(....)....................................
...(.....)...(.((....)))...........................................................(....)....................................
>AAGW02035950.1/13970-13846
CACCGUUUCAGUGGCAUUUAAGUCCCCGGCGCUCCUCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCUCAGGAGGCGGCAGAAGCUGCGGCGGCUGCAACUGCAGCUUCACAGCCCUGGG
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
...(.....)......(....)......................................................................(....)...........................
>AC116662.1/86579-86455
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUGUAGGUGACGCGCGCUCGCCCCCCCAGGCAGCCCGGGCCGCGGCGGUAGCUACGGCCGCUGCCGGAGCUGACUUGGAGCAUUGGG
...(.....)...................................................................................................................
...(.....)......(....).......................................................................................................
>AAYZ01055278.1/10927-11050
CACCGUUUCAGUGGCAUUUAAGUCCCGGCGCUCCUCGGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCGGCCCAGGAGGCGGCAGAAGCUGCGGUGGCUGCCAACGCAGCUUCACAGCUCUGGG
...(.....)..................................................................................................................
...(.....)......(....)......................................................................................................
>ABRT010305835.1/90-212
CACCAUUUCAGUGGCAUUUAAAUCCCCGGCGCUUCUCCGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAACCCAAGAGGCGGCAGCAGCUGCGGCGGCUGCCACGGCAGAUUCGGUGCUGGG
.....................................(.....)...............................................................................

ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio
1 (GUYUN) < 0.001 17.6
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
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2 (UUNA) < 0.001 10.6
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
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3 ((Y)CC)C < 0.001 4.43
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
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4 (.NGCR.) < 0.001 7.23
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
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5 G(C(A)) < 0.001 13.9
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
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6 C(A(C)) < 0.001 6.26
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
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ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio

NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio
1 (GUYUN) < 0.001 17.6
AAFC03094354.1/97532-97659
CACCGUUUCAGUGGCAUUUAAAUCCCCGGCGCUCCUCAGUCUAGGUGACGCGCAGUCGCCCCCCCAGGCAGCCUGGGCGGCGGCAGCAGCAGCUGCGGCGGCCGCAGGGGCAGAAGCGGAGCGCUAAG
...................................................................................................1............................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2........
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678
NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).