D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major

D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences

J. Mol. Biol., 435 (2023)

mir-192/215 microRNA precursor (Rfam: RF00130)

Options

Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN

Rfam

D-ORB

Augmented

((Y)Y)N
((Y)N)N
(.NNYYN.)
(N()RC)

100.0
100.0
94.9
87.2

((Y)Y)N
(.NNYYN.)

% of positive sequence with ORB

Job*

Email*

Sequence(s)*

Obtain

One structure matching the consensus structure ORBs
Several structures containing instances of most discriminative ORBs

Up to structures per sequence

Position offset nucleotides

Job*

Email*

Wildtype sequence*

Mutant sequences

All SNPs
Submit mutant sequences

Use the mutation generator

Deep neural network:

5-fold cross-validation: 99.4 %
(± 0.146 %)

Decision tree:

5-fold cross-validation: 92.7 %
(± 4.66 %)

D-ORB structure

D-ORB structure decision tree:

5-fold cross-validation: 92.7 %
(± 4.66 %)

of AANN01206173.1/3045-3149

AANN01206173.1/3045-3149

UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC
((((((.((.(((((((((((((((((((((.(((((((((((((((((.....)))))))))))))))).).)))))))))))))))))))))..)))))))).
...................................................................................................1.....
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.....
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abstract shape: `()`

					Number of sequences
	Structure	ORBs			(out of 39)	(%)
1		((Y)Y)N			38	97.4
>AAFR03023364.1/184964-184859 AGUAAGAAAUGGUGUGUAGGAAAAUGACCUAUGAAUUGACAGACAUUAUAUUUAAAGUUUGUCUGUCAUUUCUGUAGGCCAAUGCCUUGUAUGUCUGUGCUGCUUC ...............................((......................................).)................................ >AAPN01160419.1/4341-4444 AGGAAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUAUAUUUAGAUUGUCUGUCAUUUCUGUAGGCCAAAGUUCUGCAUGCCUUCACUGCUCC ...............................((....................................).)................................ >AANG01032370.1/112-8 ACUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUUUGCCUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUUCUACUUC ...............................((.....................................).)................................ >AAIY01186786.1/2491-2595 AUCAAGAAACAGCGCACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGGCCAAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUGUCUCUGCUACUUC ...............................((.....................................).)................................ >AAFC03085979.1/1681-1785 AUUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAACGUGACUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUGUUCUGUAUAUCUCUGCGACUUC ...............................((.....................................).)................................ >AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ...............................((.....................................).)................................ >AAHX01009308.1/1254-1145 GUCAAGAUGGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUGAUCUCGCCUCUGGCUGCCAGUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((......................................).).................................. >AAHX01077280.1/19936-20038 ACCAUGACCGGUGUACAGGACAAUGACCUAUGAUUUGACAGACAGUGUGGCUGCGUGUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCUCUCCUCCUUA ..............................((....................................).)................................ >AAWZ02006025.1/14732-14632 AAAUGGAGGCUUAGGGUAAUGACCUAUGAUUUGACAGACUGUGCUUUCUAUGUCUGCCUGUCAUUUCUGUAGGCCAAUACUCUGUACGCCCUCACUACUCU ..........................((......................................).)................................ >AY866319.1/760-864 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACACUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((.....................................).)................................ >AP001187.5/97046-96937 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCGUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((......................................).).................................. >AAGW02025725.1/27838-27734 AAAGAGAAUUGGUAUAUAGGAAAUUGACCUAUGAAAUGACAGAUGAUAUGGCUAAAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUACCUCUGCUGCUUC ...............................((.....................................).)................................ >AANH01000564.1/249533-249430 GAAGAGCGAUGGGACACAAAGCGAUGACCUAUUAAUUGACAGCCAGUGGUUGUAAACUCUGCCUGUCAGUUCUCUAGGCCACUGCUGUGUUUCUCCCUCCCGAA ...............................(.(.....................................).).............................. >AAKN02038532.1/88187-88078 CCCAAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUGUCAGCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCUGC .................................((......................................).).................................. >AY866321.1/496-600 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUACAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUACAACUGUGCUACUUC ...............................((.....................................).)................................ >AAEX03018351.1/31201-31097 ACUAAAAAAUGGUGUACAGGAAAAUGACCUACGAAUUGAUAGACAAUUUGGCUAAGUUUGUCUGUCAUUUUUGUAGGCCAAUAUUCUGUAUAUCUCUUCUGCUUC ...............................((.....................................).)................................ >AADA01191401.1/22670-22775 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((......................................).)................................ >AAGU03077813.1/8708-8606 ACUCAGAAACGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUAUGGCUAAGUUUGUCUGUCAUUUCUGUAGGCCAACAUUCUGUAUGUCUGCUACUUC ...............................((.....................................).).............................. >CAAE01014650.1/773661-773759 CCUGGGACACGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUGCGUCCGUCCCCCUUCUCUA ........................((......................................).)................................ >AAPY01700927.1/1101-997 AUUAACAAAUGGUAUACAGGAAAAUGACCUAUGACUUGACAGACAAUGUGGCUAGUUCUGUCUGUCAUUUCCGUAGGCCAAUAUUCUGUAUAUCUCUGCUGCUUC ...............................((.....................................).)................................ >AANN01720898.1/1196-1090 GCAGAGACAGAGUGCGCAGGGCUCUGACCUAUGACUUGACAGCCAGUGCCCUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ................................((.....................................).)................................. >CAAB02009490.1/73889-73791 CUUGGGACGUGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUACGUUUGUCCCCUUGACCUG ........................((......................................).)................................ >AAPE02028384.1/76917-77021 ACUAACAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUGUGGCUAAGUGUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCGACGACUUC ...............................((.....................................).)................................ >AC103590.2/170923-170819 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((.....................................).)................................ >AC127556.4/107222-107331 GCCAAGAUGGCGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUUUUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC .................................((......................................).).................................. >AACN010376920.1/1185-1295 GCUGAGAUCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCAUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAAGGUAUGUUCGCCUCAAUGCCAGC .................................((......................................).)................................... >AY866322.1/453-557 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGACCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((.....................................).)................................ >AAGV020435009.1/397-505 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCUAGUGCUGUUGUCCGCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((.....................................).).................................. >AAHY01149687.1/2360-2462 AGCAUCAACGGUGUACAGGAGAAUGACCUAUGAUUUGACAGACCGUGCAGCUGUGUAUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCACUGCUACUUA ..............................((....................................).)................................ >AAYZ01125558.1/348-240 GGUGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCCCCGUCUGCCCUCUGGCUGCCAAUUGCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((.....................................).).................................. >AALT01482191.1/6358-6456 GGGAGGAGCGGGACACAGGAACAUGACCUAUGAACUGACAGACAGUGGCUCGCCUGCCUGUCACUUCCAUAGGCCAAAUUCUGUGGCCCACUGGCACUU ..............................((..................................).).............................. >AAKN02018928.1/14074-14177 UUACCGAGUGGGGUGCAGGAGUAUGACCUACAAAUUGACAGACGAUGUGCCUGAGUCUGUCUGUCACUUCUGUAGGCCAACAUCCUGUACUCCGCCUCAACCCC ..............................((.....................................).)................................ >BAAE01291848.1/722-616 GAAAAGAGUUUGGGCACAAGGUGAUGACCUAUGAAUUGACAGCCAGUUACUUCUAACACCUGCCUGUCAGUUCUGUAGGCCACUGCUGCGUUUGUCCUCCUGAGCAC ................................((.....................................).)................................. >AAQR03078873.1/354-250 GUUCAGAGGUGGUAUACAGGAAAUUGACCUAUAAACUGACAGAUAAUACGGCUCCAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGCAUGUCUUUGCUACUUC ...............................((.....................................).)................................ >BX248510.4/109218-109112 GUUAAGUCUAGGACACAGGGUGAUGACCUAUGAAUUGACAGCCAGUGUUUGCAGUCCAGCUGCCUGUCAGUUCUGUAGGCCACUGCCCUGUUUAUCCUACUAAACAC ...............................((......................................).)................................. >AAIY01704218.1/882-773 GCCCAGACCGAGUGCACAAGUCUCUGACCUAUGAAUUGACAGCCAGUGCCUUGGGCUCCCCUCUGGCUGCCAAUACCAUAGGUCACAGGUAUGUUUGCCUCCAUGCCAGC ...............................(.(.........................................).)................................ >AAWR02033463.1/86334-86230 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGACUAAGUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUGCUACUUC ...............................((.....................................).)................................ >AADN03003271.1/75837-75734 AGUAAGAACUGGUGUCCAGGAAAAUGACCUAUGAAUUGACAGACUGCUUUCAAAAUGUGCCUGUCAUUUCUAUAGGCCAAUAUUCUGUGCACUUUUCCUACUUU ...............................((....................................).)................................
2		((Y)Y)N ((Y)N)N			38	97.4
>AADA01191401.1/22670-22775 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((......................................).).).............................. >AAHX01077280.1/19936-20038 ACCAUGACCGGUGUACAGGACAAUGACCUAUGAUUUGACAGACAGUGUGGCUGCGUGUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCUCUCCUCCUUA .....(.(.(.................................................................................).).)....... >AAEX03018351.1/31201-31097 ACUAAAAAAUGGUGUACAGGAAAAUGACCUACGAAUUGAUAGACAAUUUGGCUAAGUUUGUCUGUCAUUUUUGUAGGCCAAUAUUCUGUAUAUCUCUUCUGCUUC ...............................(.((.................................).).)................................ >AANN01720898.1/1196-1090 GCAGAGACAGAGUGCGCAGGGCUCUGACCUAUGACUUGACAGCCAGUGCCCUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ..............................(.((.....................................).).)............................... >AY866321.1/496-600 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUACAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUACAACUGUGCUACUUC .............................(.((.....................................).).).............................. >AAFC03085979.1/1681-1785 AUUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAACGUGACUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUGUUCUGUAUAUCUCUGCGACUUC ..........................................(.((..........).).)............................................ >AAWZ02006025.1/14732-14632 AAAUGGAGGCUUAGGGUAAUGACCUAUGAUUUGACAGACUGUGCUUUCUAUGUCUGCCUGUCAUUUCUGUAGGCCAAUACUCUGUACGCCCUCACUACUCU .....(((.................................................................................).).)....... >AAPY01700927.1/1101-997 AUUAACAAAUGGUAUACAGGAAAAUGACCUAUGACUUGACAGACAAUGUGGCUAGUUCUGUCUGUCAUUUCCGUAGGCCAAUAUUCUGUAUAUCUCUGCUGCUUC ..............................(.((...................................).).)............................... >AY866322.1/453-557 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGACCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((.....................................).).).............................. >AANH01000564.1/249533-249430 GAAGAGCGAUGGGACACAAAGCGAUGACCUAUUAAUUGACAGCCAGUGGUUGUAAACUCUGCCUGUCAGUUCUCUAGGCCACUGCUGUGUUUCUCCCUCCCGAA ..............................(.((....................................).).)............................. >AAGW02025725.1/27838-27734 AAAGAGAAUUGGUAUAUAGGAAAUUGACCUAUGAAAUGACAGAUGAUAUGGCUAAAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUACCUCUGCUGCUUC .....(.(.(....................................................................................).).)...... >AAHX01009308.1/1254-1145 GUCAAGAUGGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUGAUCUCGCCUCUGGCUGCCAGUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((........................................).).)............................... >AACN010376920.1/1185-1295 GCUGAGAUCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCAUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((........................................).).)................................ >AAGV020435009.1/397-505 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCUAGUGCUGUUGUCCGCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((.......................................).).)............................... >AANG01032370.1/112-8 ACUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUUUGCCUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUUCUACUUC ..........................................(.((..........).).)............................................ >AY866319.1/760-864 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACACUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((.....................................).).).............................. >AAPE02028384.1/76917-77021 ACUAACAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUGUGGCUAAGUGUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCGACGACUUC .....((...(..................................................................................).).)....... >CAAB02009490.1/73889-73791 CUUGGGACGUGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUACGUUUGUCCCCUUGACCUG .(.((...................................................................................).).)...... >AAKN02038532.1/88187-88078 CCCAAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUGUCAGCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCUGC ..............................(.((........................................).).)............................... >AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ..............................(.((...................................).).)............................... >AP001187.5/97046-96937 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCGUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((........................................).).)............................... >AAYZ01125558.1/348-240 GGUGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCCCCGUCUGCCCUCUGGCUGCCAAUUGCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .........(((....................................................................................).).)........ >BX248510.4/109218-109112 GUUAAGUCUAGGACACAGGGUGAUGACCUAUGAAUUGACAGCCAGUGUUUGCAGUCCAGCUGCCUGUCAGUUCUGUAGGCCACUGCCCUGUUUAUCCUACUAAACAC .............................(.((......................................).).)............................... >AAKN02018928.1/14074-14177 UUACCGAGUGGGGUGCAGGAGUAUGACCUACAAAUUGACAGACGAUGUGCCUGAGUCUGUCUGUCACUUCUGUAGGCCAACAUCCUGUACUCCGCCUCAACCCC .............................(.((...................................).).)............................... >AAPN01160419.1/4341-4444 AGGAAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUAUAUUUAGAUUGUCUGUCAUUUCUGUAGGCCAAAGUUCUGCAUGCCUUCACUGCUCC ..............................(.((..................................).).)............................... >BAAE01291848.1/722-616 GAAAAGAGUUUGGGCACAAGGUGAUGACCUAUGAAUUGACAGCCAGUUACUUCUAACACCUGCCUGUCAGUUCUGUAGGCCACUGCUGCGUUUGUCCUCCUGAGCAC ...(.((..........................................................................................).).)..... >AALT01482191.1/6358-6456 GGGAGGAGCGGGACACAGGAACAUGACCUAUGAACUGACAGACAGUGGCUCGCCUGCCUGUCACUUCCAUAGGCCAAAUUCUGUGGCCCACUGGCACUU .............................(.((................................).).)............................. >AAQR03078873.1/354-250 GUUCAGAGGUGGUAUACAGGAAAUUGACCUAUAAACUGACAGAUAAUACGGCUCCAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGCAUGUCUUUGCUACUUC ..............................(.((...................................).).)............................... >AC127556.4/107222-107331 GCCAAGAUGGCGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUUUUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ............((.(.............................................................................).).)............ >AAIY01704218.1/882-773 GCCCAGACCGAGUGCACAAGUCUCUGACCUAUGAAUUGACAGCCAGUGCCUUGGGCUCCCCUCUGGCUGCCAAUACCAUAGGUCACAGGUAUGUUUGCCUCCAUGCCAGC ........(((........................................................................................).).)...... >AADN03003271.1/75837-75734 AGUAAGAACUGGUGUCCAGGAAAAUGACCUAUGAAUUGACAGACUGCUUUCAAAAUGUGCCUGUCAUUUCUAUAGGCCAAUAUUCUGUGCACUUUUCCUACUUU ..............................(.((..................................).).)............................... >CAAE01014650.1/773661-773759 CCUGGGACACGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUGCGUCCGUCCCCCUUCUCUA .......................(.((....................................).).)............................... >AAIY01186786.1/2491-2595 AUCAAGAAACAGCGCACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGGCCAAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUGUCUCUGCUACUUC .........(.(.(...............................................................................).).)....... >AAGU03077813.1/8708-8606 ACUCAGAAACGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUAUGGCUAAGUUUGUCUGUCAUUUCUGUAGGCCAACAUUCUGUAUGUCUGCUACUUC ..............................(.((...................................).).)............................. >AAWR02033463.1/86334-86230 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGACUAAGUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUGCUACUUC ..............................(.((...................................).).)............................... >AC103590.2/170923-170819 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((.....................................).).).............................. >AAFR03023364.1/184964-184859 AGUAAGAAAUGGUGUGUAGGAAAAUGACCUAUGAAUUGACAGACAUUAUAUUUAAAGUUUGUCUGUCAUUUCUGUAGGCCAAUGCCUUGUAUGUCUGUGCUGCUUC ...............(.((..................................................................).).)................ >AAHY01149687.1/2360-2462 AGCAUCAACGGUGUACAGGAGAAUGACCUAUGAUUUGACAGACCGUGCAGCUGUGUAUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCACUGCUACUUA .............................(.((..................................).).)...............................
3		((Y)Y)N ((Y)N)N (.NNYYN.)			35	89.7
>AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ..............................(.((..............(.....)..............).).)............................... >CAAE01014650.1/773661-773759 CCUGGGACACGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUGCGUCCGUCCCCCUUCUCUA .......................(.((............(..........)............).).)............................... >CAAB02009490.1/73889-73791 CUUGGGACGUGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUACGUUUGUCCCCUUGACCUG .(.((..................................(..........).....................................).).)...... >AAPY01700927.1/1101-997 AUUAACAAAUGGUAUACAGGAAAAUGACCUAUGACUUGACAGACAAUGUGGCUAGUUCUGUCUGUCAUUUCCGUAGGCCAAUAUUCUGUAUAUCUCUGCUGCUUC ..............................(.((..............(.....)..............).).)............................... >AC103590.2/170923-170819 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((...............(.....)...............).).).............................. >AAQR03078873.1/354-250 GUUCAGAGGUGGUAUACAGGAAAUUGACCUAUAAACUGACAGAUAAUACGGCUCCAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGCAUGUCUUUGCUACUUC ..............................(.((..............(.....)..............).).)............................... >AAEX03018351.1/31201-31097 ACUAAAAAAUGGUGUACAGGAAAAUGACCUACGAAUUGAUAGACAAUUUGGCUAAGUUUGUCUGUCAUUUUUGUAGGCCAAUAUUCUGUAUAUCUCUUCUGCUUC ...............................(.((.............(.....).............).).)................................ >AAGU03077813.1/8708-8606 ACUCAGAAACGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUAUGGCUAAGUUUGUCUGUCAUUUCUGUAGGCCAACAUUCUGUAUGUCUGCUACUUC ..............................(.((..............(.....)..............).).)............................. >AAFC03085979.1/1681-1785 AUUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAACGUGACUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUGUUCUGUAUAUCUCUGCGACUUC ..........................................(.((..(.....).).).)............................................ >AADA01191401.1/22670-22775 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((...............(......)...............).).).............................. >AANG01032370.1/112-8 ACUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUUUGCCUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUUCUACUUC ..........................................(.((..(.....).).).)............................................ >AY866319.1/760-864 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACACUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((...............(.....)...............).).).............................. >AAKN02018928.1/14074-14177 UUACCGAGUGGGGUGCAGGAGUAUGACCUACAAAUUGACAGACGAUGUGCCUGAGUCUGUCUGUCACUUCUGUAGGCCAACAUCCUGUACUCCGCCUCAACCCC .............................(.((..............(.....)..............).).)............................... >AANN01720898.1/1196-1090 GCAGAGACAGAGUGCGCAGGGCUCUGACCUAUGACUUGACAGCCAGUGCCCUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ..............................(.((...............(.....)...............).).)............................... >AAPN01160419.1/4341-4444 AGGAAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUAUAUUUAGAUUGUCUGUCAUUUCUGUAGGCCAAAGUUCUGCAUGCCUUCACUGCUCC ..............................(.((..............(.....).............).).)............................... >AAWR02033463.1/86334-86230 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGACUAAGUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUGCUACUUC ..............................(.((..............(.....)..............).).)............................... >AY866321.1/496-600 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUACAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUACAACUGUGCUACUUC .............................(.((...............(.....)...............).).).............................. >AADN03003271.1/75837-75734 AGUAAGAACUGGUGUCCAGGAAAAUGACCUAUGAAUUGACAGACUGCUUUCAAAAUGUGCCUGUCAUUUCUAUAGGCCAAUAUUCUGUGCACUUUUCCUACUUU ..............................(.((............(.....)...............).).)............................... >AAKN02038532.1/88187-88078 CCCAAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUGUCAGCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCUGC ..............................(.((................(.......)...............).).)............................... >AACN010376920.1/1185-1295 GCUGAGAUCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCAUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((...............(........)...............).).)................................ >AAWZ02006025.1/14732-14632 AAAUGGAGGCUUAGGGUAAUGACCUAUGAUUUGACAGACUGUGCUUUCUAUGUCUGCCUGUCAUUUCUGUAGGCCAAUACUCUGUACGCCCUCACUACUCU .....(((.................................(..........)....................................).).)....... >AP001187.5/97046-96937 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCGUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((...............(........)...............).).)............................... >AAGV020435009.1/397-505 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCUAGUGCUGUUGUCCGCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((...............(.......)...............).).)............................... >AALT01482191.1/6358-6456 GGGAGGAGCGGGACACAGGAACAUGACCUAUGAACUGACAGACAGUGGCUCGCCUGCCUGUCACUUCCAUAGGCCAAAUUCUGUGGCCCACUGGCACUU .............................(.((.............(.....)............).).)............................. >AAHY01149687.1/2360-2462 AGCAUCAACGGUGUACAGGAGAAUGACCUAUGAUUUGACAGACCGUGCAGCUGUGUAUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCACUGCUACUUA .............................(.((..............(.....).............).).)............................... >AAHX01077280.1/19936-20038 ACCAUGACCGGUGUACAGGACAAUGACCUAUGAUUUGACAGACAGUGUGGCUGCGUGUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCUCUCCUCCUUA .....(.(.(..................................(...........)..................................).).)....... >BX248510.4/109218-109112 GUUAAGUCUAGGACACAGGGUGAUGACCUAUGAAUUGACAGCCAGUGUUUGCAGUCCAGCUGCCUGUCAGUUCUGUAGGCCACUGCCCUGUUUAUCCUACUAAACAC .............................(.((...............(........).............).).)............................... >AAIY01186786.1/2491-2595 AUCAAGAAACAGCGCACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGGCCAAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUGUCUCUGCUACUUC .........(.(.(...............................(...........)...................................).).)....... >AY866322.1/453-557 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGACCAAUAUUCUGUAUGACUGUGCUACUUC .............................(.((...............(.....)...............).).).............................. >AAHX01009308.1/1254-1145 GUCAAGAUGGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUGAUCUCGCCUCUGGCUGCCAGUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ..............................(.((...............(........)...............).).)............................... >AAPE02028384.1/76917-77021 ACUAACAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUGUGGCUAAGUGUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCGACGACUUC .....((...(....................................(.......).....................................).).)....... >AAFR03023364.1/184964-184859 AGUAAGAAAUGGUGUGUAGGAAAAUGACCUAUGAAUUGACAGACAUUAUAUUUAAAGUUUGUCUGUCAUUUCUGUAGGCCAAUGCCUUGUAUGUCUGUGCUGCUUC ...............(.((...........................(..........)...........................).).)................ >AC127556.4/107222-107331 GCCAAGAUGGCGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUUUUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ............((.(..............................(..............)...............................).).)............ >AAYZ01125558.1/348-240 GGUGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCCCCGUCUGCCCUCUGGCUGCCAAUUGCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .........(((...................................(...........)....................................).).)........ >AAGW02025725.1/27838-27734 AAAGAGAAUUGGUAUAUAGGAAAUUGACCUAUGAAAUGACAGAUGAUAUGGCUAAAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUACCUCUGCUGCUUC .....(.(.(...................................(...........)....................................).).)......
4		((Y)Y)N ((Y)N)N (.NNYYN.) (N()RC)			24	61.5
>AAFR03023364.1/184964-184859 AGUAAGAAAUGGUGUGUAGGAAAAUGACCUAUGAAUUGACAGACAUUAUAUUUAAAGUUUGUCUGUCAUUUCUGUAGGCCAAUGCCUUGUAUGUCUGUGCUGCUUC ..(.(..........(.((...........................(..........)...........................).).)..........)..).. >AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ........(.(...................(.((..............(.....)..............).).)...................)..)........ >AY866322.1/453-557 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGACCAAUAUUCUGUAUGACUGUGCUACUUC ..(.(........................(.((...............(.....)...............).).)........................)..).. >AC127556.4/107222-107331 GCCAAGAUGGCGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUUUUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ...(.(......((.(..............................(..............)...............................).).).....)..)... >AAWR02033463.1/86334-86230 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGACUAAGUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUGCUACUUC .......(.(....................(.((..............(.....)..............).).)......................)..)..... >AALT01482191.1/6358-6456 GGGAGGAGCGGGACACAGGAACAUGACCUAUGAACUGACAGACAGUGGCUCGCCUGCCUGUCACUUCCAUAGGCCAAAUUCUGUGGCCCACUGGCACUU .......(.(...................(.((.............(.....)............).).)..................)..)....... >AAQR03078873.1/354-250 GUUCAGAGGUGGUAUACAGGAAAUUGACCUAUAAACUGACAGAUAAUACGGCUCCAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGCAUGUCUUUGCUACUUC ..(.(.........................(.((..............(.....)..............).).).........................)..).. >AAEX03018351.1/31201-31097 ACUAAAAAAUGGUGUACAGGAAAAUGACCUACGAAUUGAUAGACAAUUUGGCUAAGUUUGUCUGUCAUUUUUGUAGGCCAAUAUUCUGUAUAUCUCUUCUGCUUC ...(.(.........................(.((.............(.....).............).).)..........................)..).. >AAPY01700927.1/1101-997 AUUAACAAAUGGUAUACAGGAAAAUGACCUAUGACUUGACAGACAAUGUGGCUAGUUCUGUCUGUCAUUUCCGUAGGCCAAUAUUCUGUAUAUCUCUGCUGCUUC .(.(..........................(.((..............(.....)..............).).).........................)..).. >AY866321.1/496-600 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUACAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUACAACUGUGCUACUUC ..(.(........................(.((...............(.....)...............).).)........................)..).. >AAKN02018928.1/14074-14177 UUACCGAGUGGGGUGCAGGAGUAUGACCUACAAAUUGACAGACGAUGUGCCUGAGUCUGUCUGUCACUUCUGUAGGCCAACAUCCUGUACUCCGCCUCAACCCC .......(.(...................(.((..............(.....)..............).).)...................)..)........ >AAKN02038532.1/88187-88078 CCCAAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUGUCAGCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCUGC ...........(.(................(.((................(.......)...............).).)................)..)........... >AY866319.1/760-864 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACACUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ..(.(........................(.((...............(.....)...............).).)........................)..).. >AP001187.5/97046-96937 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCGUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ...........(.(................(.((...............(........)...............).).)................)..)........... >AAGV020435009.1/397-505 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCUAGUGCUGUUGUCCGCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ...........(.(................(.((...............(.......)...............).).)................)..)........... >AADN03003271.1/75837-75734 AGUAAGAACUGGUGUCCAGGAAAAUGACCUAUGAAUUGACAGACUGCUUUCAAAAUGUGCCUGUCAUUUCUAUAGGCCAAUAUUCUGUGCACUUUUCCUACUUU ..(.(.........................(.((............(.....)...............).).).........................)..).. >AANN01720898.1/1196-1090 GCAGAGACAGAGUGCGCAGGGCUCUGACCUAUGACUUGACAGCCAGUGCCCUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ...........(.(................(.((...............(.....)...............).).)................)..)........... >AC103590.2/170923-170819 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ..(.(........................(.((...............(.....)...............).).)........................)..).. >AACN010376920.1/1185-1295 GCUGAGAUCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCAUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAAGGUAUGUUCGCCUCAAUGCCAGC ...........(.(................(.((...............(........)...............).).).................)..)........... >AADA01191401.1/22670-22775 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ..(.(........................(.((...............(......)...............).).)........................)..).. >AAPN01160419.1/4341-4444 AGGAAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUAUAUUUAGAUUGUCUGUCAUUUCUGUAGGCCAAAGUUCUGCAUGCCUUCACUGCUCC .....(.(......................(.((..............(.....).............).).)......................)..)..... >AAHY01149687.1/2360-2462 AGCAUCAACGGUGUACAGGAGAAUGACCUAUGAUUUGACAGACCGUGCAGCUGUGUAUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCACUGCUACUUA .......(.(...................(.((..............(.....).............).).)...................)..)........ >AAHX01009308.1/1254-1145 GUCAAGAUGGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUGAUCUCGCCUCUGGCUGCCAGUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC ...........(.(................(.((...............(........)...............).).)................)..)........... >AAGU03077813.1/8708-8606 ACUCAGAAACGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUAUGGCUAAGUUUGUCUGUCAUUUCUGUAGGCCAACAUUCUGUAUGUCUGCUACUUC .......(.(....................(.((..............(.....)..............).).)....................)..).....

>AAFR03023364.1/184964-184859 AGUAAGAAAUGGUGUGUAGGAAAAUGACCUAUGAAUUGACAGACAUUAUAUUUAAAGUUUGUCUGUCAUUUCUGUAGGCCAAUGCCUUGUAUGUCUGUGCUGCUUC ...............................((......................................).)................................ ...............(.((..................................................................).).)................ ...............(.((...........................(..........)...........................).).)................ ..(.(..........(.((...........................(..........)...........................).).)..........)..).. >AAPN01160419.1/4341-4444 AGGAAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUAUAUUUAGAUUGUCUGUCAUUUCUGUAGGCCAAAGUUCUGCAUGCCUUCACUGCUCC ...............................((....................................).)................................ ..............................(.((..................................).).)............................... ..............................(.((..............(.....).............).).)............................... .....(.(......................(.((..............(.....).............).).)......................)..)..... >AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ...............................((.....................................).)................................ ..............................(.((...................................).).)............................... ..............................(.((..............(.....)..............).).)............................... ........(.(...................(.((..............(.....)..............).).)...................)..)........ >AAHX01009308.1/1254-1145 GUCAAGAUGGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUGAUCUCGCCUCUGGCUGCCAGUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((......................................).).................................. ..............................(.((........................................).).)............................... ..............................(.((...............(........)...............).).)............................... ...........(.(................(.((...............(........)...............).).)................)..)........... >AY866319.1/760-864 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACACUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((.....................................).)................................ .............................(.((.....................................).).).............................. .............................(.((...............(.....)...............).).).............................. ..(.(........................(.((...............(.....)...............).).)........................)..).. >AP001187.5/97046-96937 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCGUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((......................................).).................................. ..............................(.((........................................).).)............................... ..............................(.((...............(........)...............).).)............................... ...........(.(................(.((...............(........)...............).).)................)..)........... >AAKN02038532.1/88187-88078 CCCAAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUGUCAGCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCUGC .................................((......................................).).................................. ..............................(.((........................................).).)............................... ..............................(.((................(.......)...............).).)............................... ...........(.(................(.((................(.......)...............).).)................)..)........... >AY866321.1/496-600 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUACAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUACAACUGUGCUACUUC ...............................((.....................................).)................................ .............................(.((.....................................).).).............................. .............................(.((...............(.....)...............).).).............................. ..(.(........................(.((...............(.....)...............).).)........................)..).. >AAEX03018351.1/31201-31097 ACUAAAAAAUGGUGUACAGGAAAAUGACCUACGAAUUGAUAGACAAUUUGGCUAAGUUUGUCUGUCAUUUUUGUAGGCCAAUAUUCUGUAUAUCUCUUCUGCUUC ...............................((.....................................).)................................ ...............................(.((.................................).).)................................ ...............................(.((.............(.....).............).).)................................ ...(.(.........................(.((.............(.....).............).).)..........................)..).. >AADA01191401.1/22670-22775 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((......................................).)................................ .............................(.((......................................).).).............................. .............................(.((...............(......)...............).).).............................. ..(.(........................(.((...............(......)...............).).)........................)..).. >AAGU03077813.1/8708-8606 ACUCAGAAACGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUAUGGCUAAGUUUGUCUGUCAUUUCUGUAGGCCAACAUUCUGUAUGUCUGCUACUUC ...............................((.....................................).).............................. ..............................(.((...................................).).)............................. ..............................(.((..............(.....)..............).).)............................. .......(.(....................(.((..............(.....)..............).).)....................)..)..... >AAPY01700927.1/1101-997 AUUAACAAAUGGUAUACAGGAAAAUGACCUAUGACUUGACAGACAAUGUGGCUAGUUCUGUCUGUCAUUUCCGUAGGCCAAUAUUCUGUAUAUCUCUGCUGCUUC ...............................((.....................................).)................................ ..............................(.((...................................).).)............................... ..............................(.((..............(.....)..............).).)............................... .(.(..........................(.((..............(.....)..............).).).........................)..).. >AANN01720898.1/1196-1090 GCAGAGACAGAGUGCGCAGGGCUCUGACCUAUGACUUGACAGCCAGUGCCCUCUCCCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC ................................((.....................................).)................................. ..............................(.((.....................................).).)............................... ..............................(.((...............(.....)...............).).)............................... ...........(.(................(.((...............(.....)...............).).)................)..)........... >AC103590.2/170923-170819 AUUCAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGGCCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((.....................................).)................................ .............................(.((.....................................).).).............................. .............................(.((...............(.....)...............).).).............................. ..(.(........................(.((...............(.....)...............).).)........................)..).. >AC127556.4/107222-107331 GCCAAGAUGGCGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUACUCUUUUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCACCUCAAUGCCAGC .................................((......................................).).................................. ............((.(.............................................................................).).)............ ............((.(..............................(..............)...............................).).)............ ...(.(......((.(..............................(..............)...............................).).).....)..)... >AACN010376920.1/1185-1295 GCUGAGAUCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCUCUCAUCUCUCCUCUGGCUGCCAAUUCCAUAGGUCACAAGGUAUGUUCGCCUCAAUGCCAGC .................................((......................................).)................................... ..............................(.((........................................).).)................................ ..............................(.((...............(........)...............).).)................................ ...........(.(................(.((...............(........)...............).).).................)..)........... >AY866322.1/453-557 AUUCAGAAAUGGUAUACGGGAAAAUGACCUAUGAAUUGACAGACAAUAUAGCUGAGUUUGUCUGUCAUUUCUUUAGACCAAUAUUCUGUAUGACUGUGCUACUUC ...............................((.....................................).)................................ .............................(.((.....................................).).).............................. .............................(.((...............(.....)...............).).).............................. ..(.(........................(.((...............(.....)...............).).)........................)..).. >AAGV020435009.1/397-505 GCCGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCUAGUGCUGUUGUCCGCCUCUGGCUGCCAAUUCCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((.....................................).).................................. ..............................(.((.......................................).).)............................... ..............................(.((...............(.......)...............).).)............................... ...........(.(................(.((...............(.......)...............).).)................)..)........... >AAHY01149687.1/2360-2462 AGCAUCAACGGUGUACAGGAGAAUGACCUAUGAUUUGACAGACCGUGCAGCUGUGUAUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCACUGCUACUUA ..............................((....................................).)................................ .............................(.((..................................).).)............................... .............................(.((..............(.....).............).).)............................... .......(.(...................(.((..............(.....).............).).)...................)..)........ >AALT01482191.1/6358-6456 GGGAGGAGCGGGACACAGGAACAUGACCUAUGAACUGACAGACAGUGGCUCGCCUGCCUGUCACUUCCAUAGGCCAAAUUCUGUGGCCCACUGGCACUU ..............................((..................................).).............................. .............................(.((................................).).)............................. .............................(.((.............(.....)............).).)............................. .......(.(...................(.((.............(.....)............).).)..................)..)....... >AAKN02018928.1/14074-14177 UUACCGAGUGGGGUGCAGGAGUAUGACCUACAAAUUGACAGACGAUGUGCCUGAGUCUGUCUGUCACUUCUGUAGGCCAACAUCCUGUACUCCGCCUCAACCCC ..............................((.....................................).)................................ .............................(.((...................................).).)............................... .............................(.((..............(.....)..............).).)............................... .......(.(...................(.((..............(.....)..............).).)...................)..)........ >AAQR03078873.1/354-250 GUUCAGAGGUGGUAUACAGGAAAUUGACCUAUAAACUGACAGAUAAUACGGCUCCAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGCAUGUCUUUGCUACUUC ...............................((.....................................).)................................ ..............................(.((...................................).).)............................... ..............................(.((..............(.....)..............).).)............................... ..(.(.........................(.((..............(.....)..............).).).........................)..).. >AAWR02033463.1/86334-86230 AUUAAGAAAUGGUAUACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGACUAAGUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUGCUACUUC ...............................((.....................................).)................................ ..............................(.((...................................).).)............................... ..............................(.((..............(.....)..............).).)............................... .......(.(....................(.((..............(.....)..............).).)......................)..)..... >AADN03003271.1/75837-75734 AGUAAGAACUGGUGUCCAGGAAAAUGACCUAUGAAUUGACAGACUGCUUUCAAAAUGUGCCUGUCAUUUCUAUAGGCCAAUAUUCUGUGCACUUUUCCUACUUU ...............................((....................................).)................................ ..............................(.((..................................).).)............................... ..............................(.((............(.....)...............).).)............................... ..(.(.........................(.((............(.....)...............).).).........................)..).. >AANG01032370.1/112-8 ACUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAACUGACAGACAAUUUGCCUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCUUCUACUUC ...............................((.....................................).)................................ ..........................................(.((..........).).)............................................ ..........................................(.((..(.....).).).)............................................ >AAIY01186786.1/2491-2595 AUCAAGAAACAGCGCACAGGAAAAUGACCUAUGAAUUGACAGACAAUAUGGCCAAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUGUCUCUGCUACUUC ...............................((.....................................).)................................ .........(.(.(...............................................................................).).)....... .........(.(.(...............................(...........)...................................).).)....... >AAFC03085979.1/1681-1785 AUUCAGAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAACGUGACUAAGUCUGUCUGUCAUUUCUGUAGGCCAAUGUUCUGUAUAUCUCUGCGACUUC ...............................((.....................................).)................................ ..........................................(.((..........).).)............................................ ..........................................(.((..(.....).).).)............................................ >AAHX01077280.1/19936-20038 ACCAUGACCGGUGUACAGGACAAUGACCUAUGAUUUGACAGACAGUGUGGCUGCGUGUGUCUGUCAUUCUGUAGGCCAAUAUUCUGUAUGUCUCUCCUCCUUA ..............................((....................................).)................................ .....(.(.(.................................................................................).).)....... .....(.(.(..................................(...........)..................................).).)....... >AAWZ02006025.1/14732-14632 AAAUGGAGGCUUAGGGUAAUGACCUAUGAUUUGACAGACUGUGCUUUCUAUGUCUGCCUGUCAUUUCUGUAGGCCAAUACUCUGUACGCCCUCACUACUCU ..........................((......................................).)................................ .....(((.................................................................................).).)....... .....(((.................................(..........)....................................).).)....... >AAGW02025725.1/27838-27734 AAAGAGAAUUGGUAUAUAGGAAAUUGACCUAUGAAAUGACAGAUGAUAUGGCUAAAUUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUACCUCUGCUGCUUC ...............................((.....................................).)................................ .....(.(.(....................................................................................).).)...... .....(.(.(...................................(...........)....................................).).)...... >CAAE01014650.1/773661-773759 CCUGGGACACGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUGCGUCCGUCCCCCUUCUCUA ........................((......................................).)................................ .......................(.((....................................).).)............................... .......................(.((............(..........)............).).)............................... >CAAB02009490.1/73889-73791 CUUGGGACGUGAGGUGAUGACCUAUGAAUUGACAGCCAGUAACUGGAGCCUCUGCCUGUCAGUUCUGUAGGCCACUGCUACGUUUGUCCCCUUGACCUG ........................((......................................).)................................ .(.((...................................................................................).).)...... .(.((..................................(..........).....................................).).)...... >AAPE02028384.1/76917-77021 ACUAACAAAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGACAGUGUGGCUAAGUGUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUAUCUCGACGACUUC ...............................((.....................................).)................................ .....((...(..................................................................................).).)....... .....((...(....................................(.......).....................................).).)....... >AAYZ01125558.1/348-240 GGUGAGACCGAGUGCACAGGGCUCUGACCUAUGAAUUGACAGCCAGUGCCCCGUCUGCCCUCUGGCUGCCAAUUGCAUAGGUCACAGGUAUGUUCGCCUCAAUGCCAGC .................................((.....................................).).................................. .........(((....................................................................................).).)........ .........(((...................................(...........)....................................).).)........ >BX248510.4/109218-109112 GUUAAGUCUAGGACACAGGGUGAUGACCUAUGAAUUGACAGCCAGUGUUUGCAGUCCAGCUGCCUGUCAGUUCUGUAGGCCACUGCCCUGUUUAUCCUACUAAACAC ...............................((......................................).)................................. .............................(.((......................................).).)............................... .............................(.((...............(........).............).).)............................... >AANH01000564.1/249533-249430 GAAGAGCGAUGGGACACAAAGCGAUGACCUAUUAAUUGACAGCCAGUGGUUGUAAACUCUGCCUGUCAGUUCUCUAGGCCACUGCUGUGUUUCUCCCUCCCGAA ...............................(.(.....................................).).............................. ..............................(.((....................................).).)............................. >BAAE01291848.1/722-616 GAAAAGAGUUUGGGCACAAGGUGAUGACCUAUGAAUUGACAGCCAGUUACUUCUAACACCUGCCUGUCAGUUCUGUAGGCCACUGCUGCGUUUGUCCUCCUGAGCAC ................................((.....................................).)................................. ...(.((..........................................................................................).).)..... >AAIY01704218.1/882-773 GCCCAGACCGAGUGCACAAGUCUCUGACCUAUGAAUUGACAGCCAGUGCCUUGGGCUCCCCUCUGGCUGCCAAUACCAUAGGUCACAGGUAUGUUUGCCUCCAUGCCAGC ...............................(.(.........................................).)................................ ........(((........................................................................................).).)......

	ORB			p-value	ORB frequency (per structure per nucleotide)	Means ratio
1	((Y)Y)N			< 0.001		4.8

AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ...................................................................................................1..... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0..... 123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
2	((Y)N)N			< 0.001		3

AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ...................................................................................................1..... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0..... 123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
3	(N()RC)			< 0.001		2.14

AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ...................................................................................................1..... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0..... 123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
4	(.NNYYN.)			< 0.001		2.88

AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ...................................................................................................1..... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0..... 123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
	ORB			p-value	ORB frequency (per structure per nucleotide)	Means ratio

	NCM			p-value	NCM frequency (per structure per nucleotide)	Means ratio
1	((Y)Y)N			< 0.001		4.8

AANN01206173.1/3045-3149 UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC UCACAGACAUGGUGUACAGGAAAAUGACCUAUGAAUUGACAGAUAAUGUGGCUGAGCUUGUCUGUCAUUUCUGUAGGCCAAUAUUCUGUAUUCCACUGCUGCUUC ...................................................................................................1..... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0..... 123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
	NCM			p-value	NCM frequency (per structure per nucleotide)	Means ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).