D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major
D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences
J. Mol. Biol., 435 (2023)

mir-15 microRNA precursor family   (Rfam: RF00455)

Seed sequences
All NCMs (CSV file) (all) positive sequences (all) negative sequences (random) (training) positive sequences (training) negative sequences (testing) positive sequences (testing) negative sequences 

Options
Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN
Rfam
D-ORB
Augmented
(C()G)
(YA()NU)
(YA()YN)
(G()N)
(.UNNNR.)
(NN()NU)
(R()A)
U(N(A))
(A()U)
100.0
94.1
100.0
100.0
100.0
100.0
100.0
100.0
100.0
(YA()YN)
(G()N)
(G()N)
(.UNNNR.)
(R()A)

% of positive sequence with ORB





Deep neural network:

5-fold cross-validation: 99.7 %
(± 0.0732 %)
Decision tree:

5-fold cross-validation: 80.5 %
(± 20.2 %)
D-ORB structure
D-ORB structure decision tree:

5-fold cross-validation: 91.8 %
(± 15 %)
of AY865833.1/401-486
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.((((((.(.((..(((.(((..(.((((((..(((((.......)).)))..)))))).)..))).)))..)).).)))))).)
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456

abstract shape: ()

Number of sequences
Structure ORBs (out of 17) (%)
1 (C()G)
 16 94.1
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
>AY866300.1/461-545
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAAUACAAGGA
(.(...............................................................................).)
>CAAB02000842.1/95609-95522
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGUAACGAUGUAGAAAAGGGUGCAAGCCAUAAUCUGCUGCUUUAGAAUUUUAAGGA
.(.(................................................................................).).
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(.............................................................................).)
>GQ903793.1/262-345
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAUACAAGGA
(.(..............................................................................).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
>AANH01002998.1/16865-16950
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGAAACAAUGUGGAAAGGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(................................................................................).)
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
>AL606727.3/61589-61504
GCCUGUCGGUACUGUAGCAGCACAGAAUGGUUUGUGAGUUAUAACGGGGGUGCAGGCCGUACUGUGCUGCGGCAACAACGACAGGA
(.(................................................................................).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(................................................................................).)
>EF042973.1/240-157
CCCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUGUUGAAAAGGUGCAGGCCAUACUGUGCUGCCUCAAAAUACAAGGA
(.(..............................................................................).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(................................................................................).)
>AAVX01075355.1/1195-1112
ACUUUGUGGUGAUGUAGCAGCACAUAAUGGUUUGUGAGUUGUAUGGAGAUACAGGCCAUGUUGUGCUGCCAUAUGAACACAAGA
(.(..............................................................................).)
>CAAE01014537.1/473298-473386
CCCUUAGACUGCUUUAGCAGCGCAUCAUGGUUUGUAAUGAUGUGGAAAAAAGGUGCAAACCAUAAUUUGCUGCUUUAGAAUUUUAAGGA
.(.(.................................................................................).).
>BAAF04019869.1/1029-1115
ACCUUAGAAUGCUGUAGCAGCGCAUCAUGGUUUGAAACAGUCAGAAAAAAGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(.................................................................................).)
2 (C()G)
(YA()NU)
 13 76.5
>AY866300.1/461-545
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAAUACAAGGA
(.(....................(..(...............................)..)....................).)
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(....................................)..)..................).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(....................................)..)..................).)
>GQ903793.1/262-345
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAUACAAGGA
(.(....................(..(...............................)..)...................).)
>CAAE01014537.1/473298-473386
CCCUUAGACUGCUUUAGCAGCGCAUCAUGGUUUGUAAUGAUGUGGAAAAAAGGUGCAAACCAUAAUUUGCUGCUUUAGAAUUUUAAGGA
.(.(.................(..(.......................................)..).................).).
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(..................(..(....................................)..)..................).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(....................................)..)..................).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(..................(..(.................................)..)..................).)
>AANH01002998.1/16865-16950
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGAAACAAUGUGGAAAGGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..................(..(....................................)..)..................).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(..................(..(....................................)..)..................).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(....................................)..)..................).)
>AAVX01075355.1/1195-1112
ACUUUGUGGUGAUGUAGCAGCACAUAAUGGUUUGUGAGUUGUAUGGAGAUACAGGCCAUGUUGUGCUGCCAUAUGAACACAAGA
(.(....................(..(...............................)..)...................).)
>BAAF04019869.1/1029-1115
ACCUUAGAAUGCUGUAGCAGCGCAUCAUGGUUUGAAACAGUCAGAAAAAAGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..................(..(.....................................)..)..................).)
3 (C()G)
(YA()NU)
(YA()YN)
 12 70.6
>CAAE01014537.1/473298-473386
CCCUUAGACUGCUUUAGCAGCGCAUCAUGGUUUGUAAUGAUGUGGAAAAAAGGUGCAAACCAUAAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..................(..(........(..(...............)..)........)..)..................).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(......(..(................)..)......)..)..................).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(..................(..(........(..(............)..)........)..)..................).)
>GQ903793.1/262-345
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAUACAAGGA
(.(..........(..(....(..(...................................)..)....)..).........).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(..................(..(........(..(............)..)........)..)..................).)
>AY866300.1/461-545
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAAUACAAGGA
(.(..........(..(....(..(...................................)..)....)..)..........).)
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(......(..(................)..)......)..)..................).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(......(..(................)..)......)..)..................).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(..................(..(......(..(................)..)......)..)..................).)
>AANH01002998.1/16865-16950
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGAAACAAUGUGGAAAGGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..........(..(.......(..(..............................)..).......)..)..........).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(..................(..(.....(..(...............)..).....)..)..................).)
>BAAF04019869.1/1029-1115
ACCUUAGAAUGCUGUAGCAGCGCAUCAUGGUUUGAAACAGUCAGAAAAAAGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..........(..(.......(..(...............................)..).......)..)..........).)
4 (C()G)
(YA()NU)
(YA()YN)
(G()N)
 12 70.6
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(....(.(...........(..(........(..(............)..)........)..)...........).)....).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(....(.(...........(..(.....(..(...............)..).....)..)...........).)....).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(....(.(...........(..(........(..(............)..)........)..)...........).)....).)
>BAAF04019869.1/1029-1115
ACCUUAGAAUGCUGUAGCAGCGCAUCAUGGUUUGAAACAGUCAGAAAAAAGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..(.(.....(..(.......(..(...............................)..).......)..).....).)..).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
>CAAE01014537.1/473298-473386
CCCUUAGACUGCUUUAGCAGCGCAUCAUGGUUUGUAAUGAUGUGGAAAAAAGGUGCAAACCAUAAUUUGCUGCUUUAGAAUUUUAAGGA
(.(......(.(.........(..(........(..(...............)..)........)..).........).)......).)
>GQ903793.1/262-345
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAUACAAGGA
(.(.(.(......(..(....(..(...................................)..)....)..).....).).).)
>AANH01002998.1/16865-16950
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGAAACAAUGUGGAAAGGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..(.(.....(..(.......(..(..............................)..).......)..).....).)..).)
>AY866300.1/461-545
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAAUACAAGGA
(.(.(.(......(..(....(..(...................................)..)....)..)......).).).)
5 (C()G)
(YA()NU)
(YA()YN)
(G()N)
(.UNNNR.)
 11 64.7
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(....(.(...........(..(........(..(...(.....)..)..)........)..)...........).)....).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(....(.(...........(..(........(..(...(.....)..)..)........)..)...........).)....).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(....(.(...........(..(.....(..(...(......)....)..).....)..)...........).)....).)
>AY866300.1/461-545
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAAUACAAGGA
(.(.(.(......(..(....(..(...........(...........)...........)..)....)..)......).).).)
>BAAF04019869.1/1029-1115
ACCUUAGAAUGCUGUAGCAGCGCAUCAUGGUUUGAAACAGUCAGAAAAAAGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..(.(.....(..(.......(..(.......(.............).........)..).......)..).....).)..).)
>AANH01002998.1/16865-16950
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGAAACAAUGUGGAAAGGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(..(.(.....(..(.......(..(........(............)........)..).......)..).....).)..).)
>CAAE01014537.1/473298-473386
CCCUUAGACUGCUUUAGCAGCGCAUCAUGGUUUGUAAUGAUGUGGAAAAAAGGUGCAAACCAUAAUUUGCUGCUUUAGAAUUUUAAGGA
(.(......(.(.........(..(........(..(...(......)....)..)........)..).........).)......).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
6 (C()G)
(YA()NU)
(YA()YN)
(G()N)
(.UNNNR.)
(NN()NU)
 7 41.2
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(....(.(..(..(.....(..(........(..(...(.....)..)..)........)..).....)..)..).)....).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(....(.(..(..(.....(..(.....(..(...(......)....)..).....)..).....)..)..).)....).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(....(.(..(..(.....(..(........(..(...(.....)..)..)........)..).....)..)..).)....).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
7 (C()G)
(YA()NU)
(YA()YN)
(G()N)
(.UNNNR.)
(NN()NU)
(R()A)
 7 41.2
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(....(.(.((..(.....(..(.....(..(...(......)....)..).....)..).....)..)).).)....).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(........(..(...(.....)..)..)........)..).....)..)).).)....).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(....(.(.((..(.....(..(........(..(...(.....)..)..)........)..).....)..)).).)....).)
8 (C()G)
(YA()NU)
(YA()YN)
(G()N)
(.UNNNR.)
(NN()NU)
(R()A)
U(N(A))
 7 41.2
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(....(.(.((..(.....(..(.(......(..(...(.....)..)..)......).)..).....)..)).).)....).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(.(......(..(...(.....)..)..)......).)..).....)..)).).)....).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(....(.(.((..(.....(..(.(...(..(...(......)....)..)....))..).....)..)).).)....).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
9 (C()G)
(YA()NU)
(YA()YN)
(G()N)
(.UNNNR.)
(NN()NU)
(R()A)
U(N(A))
(A()U)
 7 41.2
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(....(.(.((..(.(.(.(..(.(......(..(...(.....)..)..)......).)..).).).)..)).).)....).)
>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.(.(.(..(.(....(..(...(.......)....)..)....).)..).).).)..)).).)....).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.(.(.(..(.(....(..(...(.......)....)..)....).)..).).).)..)).).)....).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(....(.(.((..(.(.(.(..(.(......(..(...(.....)..)..)......).)..).).).)..)).).)....).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.(.(.(..(.(....(..(...(........)...)..)....).)..).).).)..)).).)....).)
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(....(.(.((..(.(.(.(..(.(....(..(...(.......)....)..)....).)..).).).)..)).).)....).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(....(.(.((..(.(.(.(..(.(...(..(...(......)....)..)....))..).).).)..)).).)....).)

>AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
(.(..................(..(....................................)..)..................).)
(.(..................(..(......(..(................)..)......)..)..................).)
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
(.(....(.(.((..(.(.(.(..(.(....(..(...(.......)....)..)....).)..).).).)..)).).)....).)
>ABDC01320645.1/1722-1804
GCCUUAAAGUACUGUAGCAGCACAUCAUGUUUACAUACUACAGUCAGAUGCGAUCAUUAUUUGCUGCUUUAGAAAUUUAGGGA
(.(.............................................................................).)
(.(..................(..(.................................)..)..................).)
(.(..................(..(.....(..(...............)..).....)..)..................).)
(.(....(.(...........(..(.....(..(...............)..).....)..)...........).)....).)
(.(....(.(...........(..(.....(..(...(......)....)..).....)..)...........).)....).)
(.(....(.(..(..(.....(..(.....(..(...(......)....)..).....)..).....)..)..).)....).)
(.(....(.(.((..(.....(..(.....(..(...(......)....)..).....)..).....)..)).).)....).)
(.(....(.(.((..(.....(..(.(...(..(...(......)....)..)....))..).....)..)).).)....).)
(.(....(.(.((..(.(.(.(..(.(...(..(...(......)....)..)....))..).).).)..)).).)....).)
>AC119847.12/19404-19489
ACCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
(.(..................(..(....................................)..)..................).)
(.(..................(..(......(..(................)..)......)..)..................).)
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
(.(....(.(.((..(.(.(.(..(.(....(..(...(........)...)..)....).)..).).).)..)).).)....).)
>AAYZ01325292.1/263-348
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUAAUAUAGUCAAUAUGCGAAUCAUAAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
(.(..................(..(....................................)..)..................).)
(.(..................(..(......(..(................)..)......)..)..................).)
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
(.(....(.(.((..(.(.(.(..(.(....(..(...(.......)....)..)....).)..).).).)..)).).)....).)
>AY865835.1/417-502
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUACUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
(.(................................................................................).)
(.(..................(..(....................................)..)..................).)
(.(..................(..(......(..(................)..)......)..)..................).)
(.(....(.(...........(..(......(..(................)..)......)..)...........).)....).)
(.(....(.(...........(..(......(..(...(.......)....)..)......)..)...........).)....).)
(.(....(.(..(..(.....(..(......(..(...(.......)....)..)......)..).....)..)..).)....).)
(.(....(.(.((..(.....(..(......(..(...(.......)....)..)......)..).....)..)).).)....).)
(.(....(.(.((..(.....(..(.(....(..(...(.......)....)..)....).)..).....)..)).).)....).)
(.(....(.(.((..(.(.(.(..(.(....(..(...(.......)....)..)....).)..).).).)..)).).)....).)
>AAWZ02004563.1/7975-8060
GCUUUAAAGUACUCUAGCAGCACAUCAUGAUUUGUAUGUCAUAGUAAAUAUGCAAGUCAUUAUUUGCUGCUUUAGAAUUUUAAAGA
(.(................................................................................).)
(.(..................(..(....................................)..)..................).)
(.(..................(..(........(..(............)..)........)..)..................).)
(.(....(.(...........(..(........(..(............)..)........)..)...........).)....).)
(.(....(.(...........(..(........(..(...(.....)..)..)........)..)...........).)....).)
(.(....(.(..(..(.....(..(........(..(...(.....)..)..)........)..).....)..)..).)....).)
(.(....(.(.((..(.....(..(........(..(...(.....)..)..)........)..).....)..)).).)....).)
(.(....(.(.((..(.....(..(.(......(..(...(.....)..)..)......).)..).....)..)).).)....).)
(.(....(.(.((..(.(.(.(..(.(......(..(...(.....)..)..)......).)..).).).)..)).).)....).)
>ADDD01069202.1/34766-34681
GCCUUAAAGUACUCUAGCAGCACAUCAUGGUUUGCAUGCUGUAGUGAAGAUGCGAAUCAUUAUUUGCUGCUUUAGAAAUUUAAGGA
(.(................................................................................).)
(.(..................(..(....................................)..)..................).)
(.(..................(..(........(..(............)..)........)..)..................).)
(.(....(.(...........(..(........(..(............)..)........)..)...........).)....).)
(.(....(.(...........(..(........(..(...(.....)..)..)........)..)...........).)....).)
(.(....(.(..(..(.....(..(........(..(...(.....)..)..)........)..).....)..)..).)....).)
(.(....(.(.((..(.....(..(........(..(...(.....)..)..)........)..).....)..)).).)....).)
(.(....(.(.((..(.....(..(.(......(..(...(.....)..)..)......).)..).....)..)).).)....).)
(.(....(.(.((..(.(.(.(..(.(......(..(...(.....)..)..)......).)..).).).)..)).).)....).)
>AY866300.1/461-545
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAAUACAAGGA
(.(...............................................................................).)
(.(....................(..(...............................)..)....................).)
(.(..........(..(....(..(...................................)..)....)..)..........).)
(.(.(.(......(..(....(..(...................................)..)....)..)......).).).)
(.(.(.(......(..(....(..(...........(...........)...........)..)....)..)......).).).)
>AANH01002998.1/16865-16950
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGAAACAAUGUGGAAAGGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(................................................................................).)
(.(..................(..(....................................)..)..................).)
(.(..........(..(.......(..(..............................)..).......)..)..........).)
(.(..(.(.....(..(.......(..(..............................)..).......)..).....).)..).)
(.(..(.(.....(..(.......(..(........(............)........)..).......)..).....).)..).)
>CAAE01014537.1/473298-473386
CCCUUAGACUGCUUUAGCAGCGCAUCAUGGUUUGUAAUGAUGUGGAAAAAAGGUGCAAACCAUAAUUUGCUGCUUUAGAAUUUUAAGGA
.(.(.................................................................................).).
.(.(.................(..(.......................................)..).................).).
(.(..................(..(........(..(...............)..)........)..)..................).)
(.(......(.(.........(..(........(..(...............)..)........)..).........).)......).)
(.(......(.(.........(..(........(..(...(......)....)..)........)..).........).)......).)
>BAAF04019869.1/1029-1115
ACCUUAGAAUGCUGUAGCAGCGCAUCAUGGUUUGAAACAGUCAGAAAAAAGUGCGAACCAUUAUUUGCUGCUUUAGAAUUUUAAGGA
(.(.................................................................................).)
(.(..................(..(.....................................)..)..................).)
(.(..........(..(.......(..(...............................)..).......)..)..........).)
(.(..(.(.....(..(.......(..(...............................)..).......)..).....).)..).)
(.(..(.(.....(..(.......(..(.......(.............).........)..).......)..).....).)..).)
>GQ903793.1/262-345
ACCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUUUUGAAAAGGUGCAGGCCAUAUUGUGCUGCCUCAAAAUACAAGGA
(.(..............................................................................).)
(.(....................(..(...............................)..)...................).)
(.(..........(..(....(..(...................................)..)....)..).........).)
(.(.(.(......(..(....(..(...................................)..)....)..).....).).).)
>AAVX01075355.1/1195-1112
ACUUUGUGGUGAUGUAGCAGCACAUAAUGGUUUGUGAGUUGUAUGGAGAUACAGGCCAUGUUGUGCUGCCAUAUGAACACAAGA
(.(..............................................................................).)
(.(....................(..(...............................)..)...................).)
>CAAB02000842.1/95609-95522
CCCUUAGACUGCUAUAGCAGCGCAUCAUGGUUUGUAACGAUGUAGAAAAGGGUGCAAGCCAUAAUCUGCUGCUUUAGAAUUUUAAGGA
.(.(................................................................................).).
>AL606727.3/61589-61504
GCCUGUCGGUACUGUAGCAGCACAGAAUGGUUUGUGAGUUAUAACGGGGGUGCAGGCCGUACUGUGCUGCGGCAACAACGACAGGA
(.(................................................................................).)
>EF042973.1/240-157
CCCUUGGAGUAAAGUAGCAGCACAUAAUGGUUUGUGGAUGUUGAAAAGGUGCAGGCCAUACUGUGCUGCCUCAAAAUACAAGGA
(.(..............................................................................).)

ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio
1 (C()G) < 0.001 6.12
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
2 (YA()NU) < 0.001 40.2
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
3 (YA()YN) < 0.001 12.5
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
4 (R()A) < 0.001 5.17
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
5 (NN()NU) < 0.001 11
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
6 U(N(A)) < 0.001 2.59
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
7 (A()U) < 0.001 2.95
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
8 (G()N) < 0.001 3.06
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456
9 (.UNNNR.) < 0.001 5.02
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
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ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio

NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio
1 (C()G) < 0.001 6.12
AY865833.1/401-486
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
GCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGA
.........1.........2.........3.........4.........5.........6.........7.........8......
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NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).