D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major
D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences
J. Mol. Biol., 435 (2023)

Hammerhead ribozyme (type I)   (Rfam: RF00163)

Seed sequences
All NCMs (CSV file) (all) positive sequences (all) negative sequences (random) (training) positive sequences (training) negative sequences (testing) positive sequences (testing) negative sequences 

Options
Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN
Rfam
D-ORB
Augmented
(().RYGN.)
(.N.().R.)
(.AAY.)
(N()UC)
100.0
100.0
82.1
75.0
(.AAY.)

% of positive sequence with ORB





Deep neural network:

5-fold cross-validation: 99.4 %
(± 0.136 %)
Decision tree:

5-fold cross-validation: 85.1 %
(± 8.14 %)
D-ORB structure
D-ORB structure decision tree:

5-fold cross-validation: 88.6 %
(± 3.08 %)
of AF213692.1/353-397
AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
(((.((.(((.(((((((....))))))).....)))..)).)))
.........1.........2.........3.........4.....
123456789012345678901234567890123456789012345

abstract shape: ()

Number of sequences
Structure ORBs (out of 28) (%)
1 (().RYGN.)
 26 92.9
>AF036398.1/58-102
AUCUUUCUGACGAGUUUCAAAUAGGACGAAACGCGUGUCAUGGAU
..........(..(.................)....)........
>AF036741.1/118-165
AUCCAGCCGACGAGUCCCAAAUAAAACGAAACGCGCGUCAAAGUGGAU
...........((................).....)............
>AF036749.1/121-167
AUUAACAGACGAGUCCCAAAUAGGACGAAGUGACGCGCGUCCUGGAU
..............(.(..............)....)..........
>M98271.1/8-53
CGACUGCUGAGGAGUCCCACAAUAGGGCGAUACGGACGUCCAGUGC
............((................)....)..........
>AF036751.1/118-161
AUCCAGCUGACGAGUCCCAAAUAGGACGAACGCACUUCCUAGAU
.........(.(................)....)..........
>X52041.1/178-64
CUUUCCCUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAAUUUUUUUAAUAAAAGUUCACCACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
.......................................(.(...........................).....).......................................
>AF036746.1/113-157
AUCCAGCUGACCAGUCGGAAAUAGGACGAAACGCGCGUCCUGGAU
...........((................)....)..........
>AF404068.1/70-185
CUUUCCAUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAAUUUUUUUUAAUAAAAGUUCACCACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
.......................................(.(............................).....).......................................
>HE601624.1/39306472-39306516
AUCUAAAUGACGAGUCCUAAAUGGAACUAAACACAUGUGUUUGAU
......(.(...................).........)......
>AF213693.1/184-228
AUCCAACCGAUGAGUCCCAAAUAGAACGAAACCUGCGUCCUGGAU
........((....................).......)......
>AF036748.1/120-164
AUCCAGCUGACGAGUCCUAAAUAGGGUGAAACGCGCGUCCUGGAU
...........((................).....).........
>AF036395.1/119-163
CCCUGGCUGACGAGUCCCAAACAGGACGAAACGCGCGUCCUGGAU
..........((................).....)..........
>D87493.1/3564-3609
GCACUUCUGAAGAGUCCCAUGCUAGGACGAAACAGCCUUCCAGUAC
..............((.........)....)...............
>AF036393.1/119-166
AUCCAGCUGACGAGUCCCAAACAGGACGAAACGAGAGUCAAACUGCAU
...........((................).....)............
>AF404041.1/70-183
CUUUCCCUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAAUUUUUUUAUAAAAGUUCACCACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
.......................................(.(..........................).....).......................................
>D87492.1/2147-2192
CAAUUGCUGAGGAGUCCCAUAAUAGGACGAAACGGCCGUCCAGUGC
...........((................).....)..........
>AF036390.1/118-165
AUCCAACUGACGAGUGCCCAAUAGGAGGAAACGCGCGUCAAACUGCAU
...........((................).....)............
>L07513.1/246-290
AUCUAGCUGACGAGUCCCGAAUAGGAGGAAGUGCUCGUUCAAUAU
...........((................).....).........
>AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.........(.(................).....)..........
>D87492.1/743-788
GCACUGCUGAGGAGUCCCACAAUAGGACGAAACGACCGUCCAGUAC
...........((................).....)..........
>AF404073.1/70-162
CUUUCCCUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
......................................((........)....).......................................
>AF036752.1/118-162
AUCCAGCUGACGAGUCCCAAAUAGGACUUGACGCGCGUCCUGGAU
..........((................).....)..........
>AF036754.1/91-138
AUCCAGUUGACGAGUCCCAAAUUGGACGAAACGCGCGUCAAACUGGAU
...........((................).....)............
>X15619.1/121-168
AUCCAGCUGACGAGUCCCAAAUAGGACGAAACGCUCGUCAAAAUGCAU
...........((................).....)............
>AF036400.1/123-167
AUCCAGCUGACGAGUGCCAAAUAGGACGAAAUGUGCAUCCUGGAU
..........((................).....)..........
>X15620.1/19-62
GGCUAGCAGUGGAAUCCAAAUAGGACGAAACGCGCGUCCUGGAU
.........((................).....)..........
2 (().RYGN.)
(.N.().R.)
 23 82.1
>AF036400.1/123-167
AUCCAGCUGACGAGUGCCAAAUAGGACGAAAUGUGCAUCCUGGAU
.......(.(.....((.......)....).....).).......
>L07513.1/246-290
AUCUAGCUGACGAGUCCCGAAUAGGAGGAAGUGCUCGUUCAAUAU
....(.(....((................).....).....)..)
>AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.(.(.....((..................)....)......).).
>AF036390.1/118-165
AUCCAACUGACGAGUGCCCAAUAGGAGGAAACGCGCGUCAAACUGCAU
..(..(.....((................).....).....)...)..
>D87492.1/2147-2192
CAAUUGCUGAGGAGUCCCAUAAUAGGACGAAACGGCCGUCCAGUGC
..(.(.....((.................).....).....).)..
>D87492.1/743-788
GCACUGCUGAGGAGUCCCACAAUAGGACGAAACGACCGUCCAGUAC
...(.(.....((................).....)....).)...
>D87493.1/3564-3609
GCACUUCUGAAGAGUCCCAUGCUAGGACGAAACAGCCUUCCAGUAC
...(..(.......((.........)....).....).....)...
>AF036398.1/58-102
AUCUUUCUGACGAGUUUCAAAUAGGACGAAACGCGUGUCAUGGAU
.......(.(.....((.......)....).....).).......
>AF036749.1/121-167
AUUAACAGACGAGUCCCAAAUAGGACGAAGUGACGCGCGUCCUGGAU
(.(.....(.(........................)....)...).)
>AF036748.1/120-164
AUCCAGCUGACGAGUCCUAAAUAGGGUGAAACGCGCGUCCUGGAU
.....(..(.....((........).....)....)...).....
>AF036393.1/119-166
AUCCAGCUGACGAGUCCCAAACAGGACGAAACGAGAGUCAAACUGCAU
....(.(....((................).....)....)..)....
>AF036751.1/118-161
AUCCAGCUGACGAGUCCCAAAUAGGACGAACGCACUUCCUAGAU
..(.(....(.(................)....).....).)..
>AF036746.1/113-157
AUCCAGCUGACCAGUCGGAAAUAGGACGAAACGCGCGUCCUGGAU
..(.(......((................)....).....).)..
>AF036741.1/118-165
AUCCAGCCGACGAGUCCCAAAUAAAACGAAACGCGCGUCAAAGUGGAU
...(.(.....((................).....).....)..)...
>HE601624.1/39306472-39306516
AUCUAAAUGACGAGUCCUAAAUGGAACUAAACACAUGUGUUUGAU
(.(...((........................).....)...).)
>AF036395.1/119-163
CCCUGGCUGACGAGUCCCAAACAGGACGAAACGCGCGUCCUGGAU
......(.(.....((........).....)....).).......
>AF213693.1/184-228
AUCCAACCGAUGAGUCCCAAAUAGAACGAAACCUGCGUCCUGGAU
(.(.((...........................)......).).)
>X15619.1/121-168
AUCCAGCUGACGAGUCCCAAAUAGGACGAAACGCUCGUCAAAAUGCAU
...(.(.....((................).....).....)..)...
>M98271.1/8-53
CGACUGCUGAGGAGUCCCACAAUAGGGCGAUACGGACGUCCAGUGC
(.(..((...........................).....)..).)
>AF036752.1/118-162
AUCCAGCUGACGAGUCCCAAAUAGGACUUGACGCGCGUCCUGGAU
..(.(....((..................)....).....).)..
>AF404073.1/70-162
CUUUCCCUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
.....................(.....(..........((........)....)..........)...)........................
>AF036754.1/91-138
AUCCAGUUGACGAGUCCCAAAUUGGACGAAACGCGCGUCAAACUGGAU
....(.(.....((............).......).....)..)....
>X15620.1/19-62
GGCUAGCAGUGGAAUCCAAAUAGGACGAAACGCGCGUCCUGGAU
(.(....((.....................).....)....).)
3 (().RYGN.)
(.N.().R.)
(.AAY.)
 20 71.4
>AF036754.1/91-138
AUCCAGUUGACGAGUCCCAAAUUGGACGAAACGCGCGUCAAACUGGAU
....(.(.....((....(...)...).......).....)..)....
>M98271.1/8-53
CGACUGCUGAGGAGUCCCACAAUAGGGCGAUACGGACGUCCAGUGC
(.(..((........(.........)........).....)..).)
>AF036395.1/119-163
CCCUGGCUGACGAGUCCCAAACAGGACGAAACGCGCGUCCUGGAU
......(.(.....((..(...).).....)....).).......
>L07513.1/246-290
AUCUAGCUGACGAGUCCCGAAUAGGAGGAAGUGCUCGUUCAAUAU
....(.(....((.....(....).....).....).....)..)
>AF036398.1/58-102
AUCUUUCUGACGAGUUUCAAAUAGGACGAAACGCGUGUCAUGGAU
.......(.(.....((.(...).)....).....).).......
>AF036393.1/119-166
AUCCAGCUGACGAGUCCCAAACAGGACGAAACGAGAGUCAAACUGCAU
....(.(....((.....(....).....).....)....)..)....
>AF036752.1/118-162
AUCCAGCUGACGAGUCCCAAAUAGGACUUGACGCGCGUCCUGGAU
..(.(....((.....(......).....)....).....).)..
>AF036751.1/118-161
AUCCAGCUGACGAGUCCCAAAUAGGACGAACGCACUUCCUAGAU
..(.(....(.(.....(....).....)....).....).)..
>X15620.1/19-62
GGCUAGCAGUGGAAUCCAAAUAGGACGAAACGCGCGUCCUGGAU
(.(....((......(.......)......).....)....).)
>D87492.1/2147-2192
CAAUUGCUGAGGAGUCCCAUAAUAGGACGAAACGGCCGUCCAGUGC
..(.(.....((.....(.....).....).....).....).)..
>X15619.1/121-168
AUCCAGCUGACGAGUCCCAAAUAGGACGAAACGCUCGUCAAAAUGCAU
...(.(.....((.....(....).....).....).....)..)...
>AF036748.1/120-164
AUCCAGCUGACGAGUCCUAAAUAGGGUGAAACGCGCGUCCUGGAU
.....(..(.....((..(...).).....)....)...).....
>AF036749.1/121-167
AUUAACAGACGAGUCCCAAAUAGGACGAAGUGACGCGCGUCCUGGAU
(.(.....(.(......(..........)......)....)...).)
>AF036390.1/118-165
AUCCAACUGACGAGUGCCCAAUAGGAGGAAACGCGCGUCAAACUGCAU
..(..(.....((.....(....).....).....).....)...)..
>AF036400.1/123-167
AUCCAGCUGACGAGUGCCAAAUAGGACGAAAUGUGCAUCCUGGAU
.......(.(.....((.(...).)....).....).).......
>D87492.1/743-788
GCACUGCUGAGGAGUCCCACAAUAGGACGAAACGACCGUCCAGUAC
...(.(.....((.....(....).....).....)....).)...
>AF036741.1/118-165
AUCCAGCCGACGAGUCCCAAAUAAAACGAAACGCGCGUCAAAGUGGAU
...(.(.....((.....(....).....).....).....)..)...
>AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.(.(.....((.....(......).....)....)......).).
>HE601624.1/39306472-39306516
AUCUAAAUGACGAGUCCUAAAUGGAACUAAACACAUGUGUUUGAU
(.(...((......(..........)......).....)...).)
>AF036746.1/113-157
AUCCAGCUGACCAGUCGGAAAUAGGACGAAACGCGCGUCCUGGAU
..(.(......((.....(....).....)....).....).)..
4 (().RYGN.)
(.N.().R.)
(.AAY.)
(N()UC)
 10 35.7
>AF036754.1/91-138
AUCCAGUUGACGAGUCCCAAAUUGGACGAAACGCGCGUCAAACUGGAU
....(.(.(.(.((....(...)...).......).)..))..)....
>AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.(.(.(.(.((.....(......).....)....).)..).).).
>D87492.1/743-788
GCACUGCUGAGGAGUCCCACAAUAGGACGAAACGACCGUCCAGUAC
(.(..(.(...((....(.....)....)......).)..)..).)
>X15619.1/121-168
AUCCAGCUGACGAGUCCCAAAUAGGACGAAACGCUCGUCAAAAUGCAU
...(.(..(.(((.....(....).....).....))..).)..)...
>AF036746.1/113-157
AUCCAGCUGACCAGUCGGAAAUAGGACGAAACGCGCGUCCUGGAU
..(.((.(...((.....(....).....)....).)..)).)..
>AF036752.1/118-162
AUCCAGCUGACGAGUCCCAAAUAGGACUUGACGCGCGUCCUGGAU
..(.((.(.((.....(......).....)....).)..)).)..
>AF036751.1/118-161
AUCCAGCUGACGAGUCCCAAAUAGGACGAACGCACUUCCUAGAU
..(.((.(.(.(.....(....).....)....).)..)).)..
>AF036390.1/118-165
AUCCAACUGACGAGUGCCCAAUAGGAGGAAACGCGCGUCAAACUGCAU
..(..(..(.(((.....(....).....).....))..).)...)..
>D87492.1/2147-2192
CAAUUGCUGAGGAGUCCCAUAAUAGGACGAAACGGCCGUCCAGUGC
..(.((.(..((.....(.....).....).....).)..)).)..
>AF036393.1/119-166
AUCCAGCUGACGAGUCCCAAACAGGACGAAACGAGAGUCAAACUGCAU
....(.(.(.(((.....(....).....).....))..))..)....

>AF036751.1/118-161
AUCCAGCUGACGAGUCCCAAAUAGGACGAACGCACUUCCUAGAU
.........(.(................)....)..........
..(.(....(.(................)....).....).)..
..(.(....(.(.....(....).....)....).....).)..
..(.((.(.(.(.....(....).....)....).)..)).)..
>AF036746.1/113-157
AUCCAGCUGACCAGUCGGAAAUAGGACGAAACGCGCGUCCUGGAU
...........((................)....)..........
..(.(......((................)....).....).)..
..(.(......((.....(....).....)....).....).)..
..(.((.(...((.....(....).....)....).)..)).)..
>AF036393.1/119-166
AUCCAGCUGACGAGUCCCAAACAGGACGAAACGAGAGUCAAACUGCAU
...........((................).....)............
....(.(....((................).....)....)..)....
....(.(....((.....(....).....).....)....)..)....
....(.(.(.(((.....(....).....).....))..))..)....
>D87492.1/2147-2192
CAAUUGCUGAGGAGUCCCAUAAUAGGACGAAACGGCCGUCCAGUGC
...........((................).....)..........
..(.(.....((.................).....).....).)..
..(.(.....((.....(.....).....).....).....).)..
..(.((.(..((.....(.....).....).....).)..)).)..
>AF036390.1/118-165
AUCCAACUGACGAGUGCCCAAUAGGAGGAAACGCGCGUCAAACUGCAU
...........((................).....)............
..(..(.....((................).....).....)...)..
..(..(.....((.....(....).....).....).....)...)..
..(..(..(.(((.....(....).....).....))..).)...)..
>AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.........(.(................).....)..........
.(.(.....((..................)....)......).).
.(.(.....((.....(......).....)....)......).).
.(.(.(.(.((.....(......).....)....).)..).).).
>D87492.1/743-788
GCACUGCUGAGGAGUCCCACAAUAGGACGAAACGACCGUCCAGUAC
...........((................).....)..........
...(.(.....((................).....)....).)...
...(.(.....((.....(....).....).....)....).)...
(.(..(.(...((....(.....)....)......).)..)..).)
>AF036752.1/118-162
AUCCAGCUGACGAGUCCCAAAUAGGACUUGACGCGCGUCCUGGAU
..........((................).....)..........
..(.(....((..................)....).....).)..
..(.(....((.....(......).....)....).....).)..
..(.((.(.((.....(......).....)....).)..)).)..
>AF036754.1/91-138
AUCCAGUUGACGAGUCCCAAAUUGGACGAAACGCGCGUCAAACUGGAU
...........((................).....)............
....(.(.....((............).......).....)..)....
....(.(.....((....(...)...).......).....)..)....
....(.(.(.(.((....(...)...).......).)..))..)....
>X15619.1/121-168
AUCCAGCUGACGAGUCCCAAAUAGGACGAAACGCUCGUCAAAAUGCAU
...........((................).....)............
...(.(.....((................).....).....)..)...
...(.(.....((.....(....).....).....).....)..)...
...(.(..(.(((.....(....).....).....))..).)..)...
>AF036398.1/58-102
AUCUUUCUGACGAGUUUCAAAUAGGACGAAACGCGUGUCAUGGAU
..........(..(.................)....)........
.......(.(.....((.......)....).....).).......
.......(.(.....((.(...).)....).....).).......
>AF036741.1/118-165
AUCCAGCCGACGAGUCCCAAAUAAAACGAAACGCGCGUCAAAGUGGAU
...........((................).....)............
...(.(.....((................).....).....)..)...
...(.(.....((.....(....).....).....).....)..)...
>AF036749.1/121-167
AUUAACAGACGAGUCCCAAAUAGGACGAAGUGACGCGCGUCCUGGAU
..............(.(..............)....)..........
(.(.....(.(........................)....)...).)
(.(.....(.(......(..........)......)....)...).)
>M98271.1/8-53
CGACUGCUGAGGAGUCCCACAAUAGGGCGAUACGGACGUCCAGUGC
............((................)....)..........
(.(..((...........................).....)..).)
(.(..((........(.........)........).....)..).)
>HE601624.1/39306472-39306516
AUCUAAAUGACGAGUCCUAAAUGGAACUAAACACAUGUGUUUGAU
......(.(...................).........)......
(.(...((........................).....)...).)
(.(...((......(..........)......).....)...).)
>AF036748.1/120-164
AUCCAGCUGACGAGUCCUAAAUAGGGUGAAACGCGCGUCCUGGAU
...........((................).....).........
.....(..(.....((........).....)....)...).....
.....(..(.....((..(...).).....)....)...).....
>AF036395.1/119-163
CCCUGGCUGACGAGUCCCAAACAGGACGAAACGCGCGUCCUGGAU
..........((................).....)..........
......(.(.....((........).....)....).).......
......(.(.....((..(...).).....)....).).......
>L07513.1/246-290
AUCUAGCUGACGAGUCCCGAAUAGGAGGAAGUGCUCGUUCAAUAU
...........((................).....).........
....(.(....((................).....).....)..)
....(.(....((.....(....).....).....).....)..)
>AF036400.1/123-167
AUCCAGCUGACGAGUGCCAAAUAGGACGAAAUGUGCAUCCUGGAU
..........((................).....)..........
.......(.(.....((.......)....).....).).......
.......(.(.....((.(...).)....).....).).......
>X15620.1/19-62
GGCUAGCAGUGGAAUCCAAAUAGGACGAAACGCGCGUCCUGGAU
.........((................).....)..........
(.(....((.....................).....)....).)
(.(....((......(.......)......).....)....).)
>AF213693.1/184-228
AUCCAACCGAUGAGUCCCAAAUAGAACGAAACCUGCGUCCUGGAU
........((....................).......)......
(.(.((...........................)......).).)
>D87493.1/3564-3609
GCACUUCUGAAGAGUCCCAUGCUAGGACGAAACAGCCUUCCAGUAC
..............((.........)....)...............
...(..(.......((.........)....).....).....)...
>AF404073.1/70-162
CUUUCCCUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
......................................((........)....).......................................
.....................(.....(..........((........)....)..........)...)........................
>X52041.1/178-64
CUUUCCCUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAAUUUUUUUAAUAAAAGUUCACCACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
.......................................(.(...........................).....).......................................
>AF404068.1/70-185
CUUUCCAUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAAUUUUUUUUAAUAAAAGUUCACCACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
.......................................(.(............................).....).......................................
>AF404041.1/70-183
CUUUCCCUGAAGAGACGAAGUGAUCAAGAGAUUGAAGACGAGUGAACUAAUUUUUUUAUAAAAGUUCACCACGACUCCUCCUUCUCUCACAAGUCGAAACUCAGAGUCGGAAAG
.......................................(.(..........................).....).......................................

ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio
1 (().RYGN.) < 0.001 8.02
AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.........1.........2.........3.........4.....
123456789012345678901234567890123456789012345
2 (.AAY.) < 0.001 7.12
AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.........1.........2.........3.........4.....
123456789012345678901234567890123456789012345
3 (.N.().R.) < 0.001 2.7
AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.........1.........2.........3.........4.....
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4 (N()UC) < 0.001 4.79
AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.........1.........2.........3.........4.....
123456789012345678901234567890123456789012345
ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio

NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio
1 A(ARY)N < 0.001 9.23
AF213692.1/353-397
AUCCAGCCGAUGAGUUCCAAACAGGACUAAACGCGCUUCUUGGAU
.........1.........2.........3.........4.....
123456789012345678901234567890123456789012345
2 .NCGA. < 0.001 4.04
3 (R()UA()) < 0.001 28.5
NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).