D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major
D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences
J. Mol. Biol., 435 (2023)

microRNA mir-21   (Rfam: RF00658)

Seed sequences
All NCMs (CSV file) (all) positive sequences (all) negative sequences (random) (training) positive sequences (training) negative sequences (testing) positive sequences (testing) negative sequences 

Options
Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN
Rfam
D-ORB
Augmented
U(CA(G))
(NRNUY)
U(YG(R))
(U()G)
C(U(U))
N(NG(U))
(G()N)
U(A(U))
((A)R)C
100.0
100.0
100.0
100.0
100.0
100.0
100.0
100.0
100.0
U(CA(G))
(NRNUY)
((A)R)C

% of positive sequence with ORB





Deep neural network:

5-fold cross-validation: 99.9 %
(± 0.0559 %)
Decision tree:

5-fold cross-validation: 81.8 %
(± 13.7 %)
D-ORB structure
D-ORB structure decision tree:

5-fold cross-validation: 93.3 %
(± 9.79 %)
of AM600961.1/11-82
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
((((.((.(((.(.(..(((((.(((..((..((.....)..)).).))).))))).).).))).)).))))
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012

abstract shape: ()

Number of sequences
Structure ORBs (out of 11) (%)
1 U(CA(G))
 10 90.9
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
..............(..(......................................).)..............
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(.....................................).)..............
>AAVX01193435.1/262-191
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGCUCAGGUGGCGACAACAGUUGGUAGGCUAUCUGGCG
..............(..(.....................................).)..............
>CAAB02007460.1/51060-51132
CAUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGGUUCCCAUGGCAACAGCAGUCUGUAAGCUGUCUGAAG
..............(..(......................................).)..............
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
..............(..(.....................................).)..............
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
..............(..(.....................................).)..............
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(.....................................).)..............
>CAAE01007707.1/16214-16286
CGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUGGGUCGUCAUGGCAACAGCGGUCUGUAAGCUGUCUGAAG
..............(..(......................................).)..............
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
..............(..(......................................).)..............
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
..............(..(......................................).)..............
2 U(CA(G))
(NRNUY)
 10 90.9
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
..............(..(................(.....)...............).)..............
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
..............(..(...............(.....)................).)..............
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
..............(..(................(.....)...............).)..............
>AAVX01193435.1/262-191
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGCUCAGGUGGCGACAACAGUUGGUAGGCUAUCUGGCG
..............(..(...............(.....)...............).)..............
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(...............(.....)...............).)..............
>CAAB02007460.1/51060-51132
CAUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGGUUCCCAUGGCAACAGCAGUCUGUAAGCUGUCUGAAG
..............(..(...............(.....)................).)..............
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
..............(..(...............(.....)...............).)..............
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
..............(..(...............(.....)...............).)..............
>CAAE01007707.1/16214-16286
CGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUGGGUCGUCAUGGCAACAGCGGUCUGUAAGCUGUCUGAAG
..............(..(...............(.....)................).)..............
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(...............(.....)...............).)..............
3 U(CA(G))
(NRNUY)
U(YG(R))
 10 90.9
>CAAB02007460.1/51060-51132
CAUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGGUUCCCAUGGCAACAGCAGUCUGUAAGCUGUCUGAAG
..............(..(.......(..(....(.....)......).).......).)..............
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
..............(..(.......(..(....(.....)......).).......).)..............
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
..............(..(.......(..(.....(.....).....).).......).)..............
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(.......(..(....(.....).....).).......).)..............
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(.......(..(....(.....).....).).......).)..............
>AAVX01193435.1/262-191
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGCUCAGGUGGCGACAACAGUUGGUAGGCUAUCUGGCG
..............(..(.......(..(....(.....).....).).......).)..............
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
..............(..(.......(..(....(.....).....).).......).)..............
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
..............(..(.......(..(....(.....).....).).......).)..............
>CAAE01007707.1/16214-16286
CGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUGGGUCGUCAUGGCAACAGCGGUCUGUAAGCUGUCUGAAG
..............(..(.......(..(....(.....).....)..).......).)..............
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
..............(..(.......(..(.....(.....).....).).......).)..............
4 U(CA(G))
(NRNUY)
U(YG(R))
(U()G)
 9 81.8
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
......(.(.....(..(.......(..(....(.....)......).).......).).....).)......
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
......(.(.....(..(.......(..(.....(.....).....).).......).).....).)......
>CAAB02007460.1/51060-51132
CAUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGGUUCCCAUGGCAACAGCAGUCUGUAAGCUGUCUGAAG
......(.(.....(..(.......(..(....(.....)......).).......).).....).)......
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
......(.(.....(..(.......(..(.....(.....).....).).......).).....).)......
>CAAE01007707.1/16214-16286
CGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUGGGUCGUCAUGGCAACAGCGGUCUGUAAGCUGUCUGAAG
......(.(.....(..(.......(..(....(.....).....)..).......).).....).)......
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
5 U(CA(G))
(NRNUY)
U(YG(R))
(U()G)
C(U(U))
 9 81.8
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
>CAAE01007707.1/16214-16286
CGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUGGGUCGUCAUGGCAACAGCGGUCUGUAAGCUGUCUGAAG
......(.(.(.(.(..(.......(..(....(.....).....)..).......).).).).).)......
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
......(.(.(.(.(..(.......(..(.....(.....).....).).......).).).).).)......
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
......(.(.(.(.(..(.......(..(....(.....)......).).......).).).).).)......
>CAAB02007460.1/51060-51132
CAUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGGUUCCCAUGGCAACAGCAGUCUGUAAGCUGUCUGAAG
......(.(.(.(.(..(.......(..(....(.....)......).).......).).).).).)......
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
......(.(.(.(.(..(.......(..(.....(.....).....).).......).).).).).)......
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
6 U(CA(G))
(NRNUY)
U(YG(R))
(U()G)
C(U(U))
N(NG(U))
 8 72.7
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
......(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)......
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
......(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)......
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
>CAAB02007460.1/51060-51132
CAUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGGUUCCCAUGGCAACAGCAGUCUGUAAGCUGUCUGAAG
......(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)......
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
......(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)......
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
7 U(CA(G))
(NRNUY)
U(YG(R))
(U()G)
C(U(U))
N(NG(U))
(G()N)
 7 63.6
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
(.(...(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)...).)
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
...(.((.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)).)...
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
(.(...(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)...).)
8 U(CA(G))
(NRNUY)
U(YG(R))
(U()G)
C(U(U))
N(NG(U))
(G()N)
U(A(U))
 6 54.5
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
(.(...(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)...).)
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
(.(...(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)...).)
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
...(.((.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)).)...
9 U(CA(G))
(NRNUY)
U(YG(R))
(U()G)
C(U(U))
N(NG(U))
(G()N)
U(A(U))
((A)R)C
 5 45.5
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
(.(...(.(.(.(.(..(...(.(.(..((..((.....)..).).).).).)...).).).).).)...).)
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
...(.((.(.(.(.(..(...(.(.(..((..(.(.....)..)).).).).)...).).).).).)).)...
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
...(.((.(.(.(.(..(...(.(.(..((..((.....)..)).).).).)...).).).).).)).)...
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
...(.((.(.(.(.(..(...(.(.(..((..((.....)..)).).).).)...).).).).).)).)...
>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
(.(...(.(.(.(.(..(...(.(.(..((..(.(.....)..)).).).).)...).).).).).)...).)

>BAAF04044466.1/2035-1963
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAAGAUUGCAAGGCGACAACAGUCUGUAGGCUGUCUGACA
..............(..(......................................).)..............
..............(..(................(.....)...............).)..............
..............(..(.......(..(.....(.....).....).).......).)..............
......(.(.....(..(.......(..(.....(.....).....).).......).).....).)......
......(.(.(.(.(..(.......(..(.....(.....).....).).......).).).).).)......
......(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)......
(.(...(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)...).)
(.(...(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)...).)
(.(...(.(.(.(.(..(...(.(.(..((..(.(.....)..)).).).).)...).).).).).)...).)
>AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(.....................................).)..............
..............(..(...............(.....)...............).)..............
..............(..(.......(..(....(.....).....).).......).)..............
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
...(.((.(.(.(.(..(...(.(.(..((..((.....)..)).).).).)...).).).).).)).)...
>ABQF01026541.1/60151-60222
UGUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUGGAUCUCAUGGCAACAACAGUCGGUAGGCUGUCUGACA
..............(..(.....................................).)..............
..............(..(...............(.....)...............).)..............
..............(..(.......(..(....(.....).....).).......).)..............
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
...(.((.(.(.(.(..(...(.(.(..((..((.....)..)).).).).)...).).).).).)).)...
>BAAF04048171.1/11412-11340
UGUCGGCUAGCUUAUCAGACUGGUGUUGGAGGUUCCAUUUGCACGGCAACAACGGUCUGUAAGCUGGCUGACA
..............(..(......................................).)..............
..............(..(................(.....)...............).)..............
..............(..(.......(..(.....(.....).....).).......).)..............
......(.(.....(..(.......(..(.....(.....).....).).......).).....).)......
......(.(.(.(.(..(.......(..(.....(.....).....).).......).).).).).)......
......(.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)......
...(.((.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)).)...
...(.((.(.(.(.(..(.......(..((..(.(.....)..)).).).......).).).).).)).)...
...(.((.(.(.(.(..(...(.(.(..((..(.(.....)..)).).).).)...).).).).).)).)...
>AANH01008078.1/292800-292872
CGUCAGCUAGCUUAUCAGACUGGUGUUGGCUGUUCAAUCACCACGGCAACAGCGGUCUGUAAGCUGGCCGAAG
..............(..(......................................).)..............
..............(..(...............(.....)................).)..............
..............(..(.......(..(....(.....)......).).......).)..............
......(.(.....(..(.......(..(....(.....)......).).......).).....).)......
......(.(.(.(.(..(.......(..(....(.....)......).).......).).).).).)......
......(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)......
(.(...(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)...).)
(.(...(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)...).)
(.(...(.(.(.(.(..(...(.(.(..((..((.....)..).).).).).)...).).).).).)...).)
>AY865965.1/427-498
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACACCAGUCGAUGGGCUGUCUGACA
..............(..(.....................................).)..............
..............(..(...............(.....)...............).)..............
..............(..(.......(..(....(.....).....).).......).)..............
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>AAPN01116099.1/42432-42503
UAUCGGAUAGCUUAUCAGACUGAUGUUGACUGUUAGAUCUCCUGGCAACAGCAGUCGAUGGGCUGUCUGACA
..............(..(.....................................).)..............
..............(..(...............(.....)...............).)..............
..............(..(.......(..(....(.....).....).).......).)..............
......(.(.....(..(.......(..(....(.....).....).).......).).....).)......
......(.(.(.(.(..(.......(..(....(.....).....).).......).).).).).)......
......(.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)......
...(.((.(.(.(.(..(.......(..((..((.....)..)).).).......).).).).).)).)...
>CAAB02007460.1/51060-51132
CAUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGGUUCCCAUGGCAACAGCAGUCUGUAAGCUGUCUGAAG
..............(..(......................................).)..............
..............(..(...............(.....)................).)..............
..............(..(.......(..(....(.....)......).).......).)..............
......(.(.....(..(.......(..(....(.....)......).).......).).....).)......
......(.(.(.(.(..(.......(..(....(.....)......).).......).).).).).)......
......(.(.(.(.(..(.......(..((..((.....)..).).).).......).).).).).)......
>CAAE01007707.1/16214-16286
CGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUGGGUCGUCAUGGCAACAGCGGUCUGUAAGCUGUCUGAAG
..............(..(......................................).)..............
..............(..(...............(.....)................).)..............
..............(..(.......(..(....(.....).....)..).......).)..............
......(.(.....(..(.......(..(....(.....).....)..).......).).....).)......
......(.(.(.(.(..(.......(..(....(.....).....)..).......).).).).).)......
>AAVX01193435.1/262-191
UGUCAGAUAGCUUAUCAGACUGGUGUUGGCUGUUAGCUCAGGUGGCGACAACAGUUGGUAGGCUAUCUGGCG
..............(..(.....................................).)..............
..............(..(...............(.....)...............).)..............
..............(..(.......(..(....(.....).....).).......).)..............

ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio
1 U(CA(G)) < 0.001 7.58
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
2 (NRNUY) < 0.001 10.4
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
3 U(YG(R)) < 0.001 5.19
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
4 (U()G) < 0.001 9.56
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
5 (G()N) < 0.001 5.45
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
6 U(A(U)) < 0.001 11.7
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
7 C(U(U)) < 0.001 2.23
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
8 ((A)R)C < 0.001 2.05
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
9 N(NG(U)) < 0.001 4.05
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio

NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio
1 U(CA(G)) < 0.001 7.58
AM600961.1/11-82
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
UGUCGGGUAGCUUAUCAGACUGAUGUUGACUGUUGAAUCUCAUGGCAACAGCAGUCGAUGGGCUGUCUGACA
.........1.........2.........3.........4.........5.........6.........7..
123456789012345678901234567890123456789012345678901234567890123456789012
NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).