D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major

D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences

J. Mol. Biol., 435 (2023)

S-adenosyl methionine (SAM) riboswitch_ (Rfam: RF00634)

Options

Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN

Rfam

D-ORB

Augmented

C(CN)G
((G)C)G
(()()(R)N)G
G(UG)C
(.GNN.().N.)

92.5
97.5
97.5
82.5
85.0

C(CN)G
((G)C)G
(.GNN.().N.)

% of positive sequence with ORB

Job*

Email*

Sequence(s)*

Obtain

One structure matching the consensus structure ORBs
Several structures containing instances of most discriminative ORBs

Up to structures per sequence

Position offset nucleotides

Job*

Email*

Wildtype sequence*

Mutant sequences

All SNPs
Submit mutant sequences

Use the mutation generator

Deep neural network:

5-fold cross-validation: 99.3 %
(± 0.221 %)

Decision tree:

5-fold cross-validation: 90.9 %
(± 6.77 %)

D-ORB structure

D-ORB structure decision tree:

5-fold cross-validation: 86.1 %
(± 11.5 %)

of CP000580.1/1312753-1312635

CP000580.1/1312753-1312635

GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC
.(((((((((((((((....((((..)))).)))))).((((((((((.....).).(((((..))))))).)))))).(.((((((((((((...))))))))))))).)))))))))
...................................................................................................1...................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........
12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789

abstract shape: `(()(()())())`

					Number of sequences
	Structure	ORBs			(out of 40)	(%)
1		C(CN)G			37	92.5
>CT573213.2/4831346-4831458 UGUCACGAGUGCCAACGUCCAGCCCCGGCUUGUUGGCCGGCAACCCUCCACCGCGAAGGGGUGCCCCGGGUGAGGACACGGCCGCAUCCAGUGGAGGCGGCAAAGCGCGGGCC .......................(..)...................................................................................... >AAGP01000018.1/74571-74460 GUUCACGAGUCGUGGCUAUCGGUACCUGGCCGGCCACGCGGCAACCCGUCAUCGACCGGGUGCCCCAGGGAAAGAACGGGCCCGCACCACGUGGUGCUGGCAAGAUUCGAUC .............................(..)............................................................................... >CP000820.1/5910611-5910498 GGUCCUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCUCCGCGGUGGGGUGCCCCGGGUGUGACCAGGCCCGCGGCGAACCCGCCGUCGGCAAGUGCGGACC ...........(..)................................................................................................... >CP000509.1/3644126-3644238 CGUCACGAGUACUGGCGCGAAGCCCCGGCUGGCCAGUCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGAGGACACGGCCGACUGCGACCGCAGCCGGCAAGCGCGGACU .......................(..)...................................................................................... >CP000656.1/5531569-5531680 GCUCACGAGCGGACGACUGUUCGGGUACCUGGCCCGUCGUCCCGGCAACCGCGCGACCACCGCACGGUGCCCCAGGGGAAGAGCGGGCACGCGGUGCGUGCAAGCGGUGGAC .......................................................................(..)..................................... >CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC .......................(..)............................................................................................ >BA000030.3/7291233-7291349 GGUCAUGAGCGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUAGGCAGCGAGGUCUACGGCAAGCGCGGACC ........................(..)......................................................................................... >CP000656.1/5194683-5194802 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGAACACGGCUAUAAGGCAAGCGCGGGUC .......................(..)............................................................................................. >CP000750.2/3280159-3280049 GGUCAUGAGUGACAGCGACAAGCCCUGGCUCGCUGUCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCAGGUGAAGACCCGGCCGGACGAAAACGUCCGGCAAGCGCGGAUC .......................(..).................................................................................... >AACY020524451.1/3761-3655 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCGACCGCGGUGGGGUGCUCCGGGUGAAGACCAGGCCUGAUAGUCAGGCAAGCGCGGGUC .......................(..)................................................................................ >AM420293.1/6539181-6539066 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAGGACCUGGCCGGUCGCGCAGGGCGACCCGGCAAGCGCGGGCC .......................(..)......................................................................................... >CP000474.1/2904762-2904875 GGUCACGAGUGCCAGCGCUAAACCCCGGUUUGCUGGCCGGCAACCCUCCAUUCGCGGUGGGGUGCCCCGGGUGACGACCCGGCCGGUCCGGAAUGGAUGCGGCAAGCGCGGAUC .......................(..)....................................................................................... >CP000431.1/6724422-6724302 GGUCAUGAGUGCCAGCAACGAGCCCCGGCUAGCUGGCCGGCAACCCUCCACCGCGGUGGGGUGCCCCGGGUGAUGACCUGGUUUCCUGAUUCACACAACAGUCGGGUGACAAGCGCGGGUC .......................(..).............................................................................................. >CP000511.1/1643745-1643626 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGGCCACGGCUAUAAGGCAAGCGCGGGUC .......................(..)............................................................................................. >AP006618.1/5665640-5665528 GGUCAUGAGCACCAGCGCCAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGCGGGGUGCUCCGGGUGACGACCUGGCCGUACCGAAGACGGUGCGGCAAGUGCGGAUU .......................(..)...................................................................................... >CP000480.1/1361993-1361882 CUUCACGAGACGCCGUCGACAAGCUCCGACUGGAUGGCGCGCCAACCCCACGCUCGUGGGUGGCUCGGAUGACGAAGCGGCCUGCACCACCCGGUGCGGGUAAGAGCGCCUC .........................................................................................(..)................... >CP000611.1/3736812-3736931 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCAUCGCCGGCUGCGCGGCAAGCGCGGGUC .......................(..)............................................................................................. >CP000474.1/1618337-1618453 GGUCAUGAGUGCCAGCACACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUCCGCGGUGGGGUGCCCCGGGUGAAGACCUGGCCUGUUCGCACGCAAGGCGACGGGCAAGCGCGAGGU ...........(..)...................................................................................................... >CT573213.2/4609200-4609314 CGUCUUGAGUGCCAGCGUUCAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUAUGCAGCGGGGUGCCCCGGGUGGUGACGAGGCCGCGGCAACCCCGCCGACGGCAAGUGCCGACC ...........(..).................................................................................................... >CP000325.1/1553430-1553311 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGUCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACAGUCGGCUACACGGCAAGCGCGGGUC .......................(..)............................................................................................. >CP000667.1/317960-317841 GGUCACGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCGUCGAGGUUCGCGGUGGGGUGCCCCGGGUGAUGACCGGGCCUGGCGCGGCGCGCGUCGGGCAAGCGCGGACC .......................(..)............................................................................................. >U00022.1/34579-34697 GGUCAUGAGCGCCAGCGUCAAGCCCCGACUUGCUGGCCGGCAACCCUCCAACCGCGUUGGAGUGCCCCGGUGAUGACCAGGUUGAGUAGCCAGAACCGGCUACGCGGCAAGCGCGAGUC .................................................................(..).................................................. >AAMN01000002.1/4575-4689 GGUCACGAGUACCAGUGUUCAGCCCCGGCUUGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGUCGGCUGCAGCAACGCAGUUGGCAAGCGCGGACU ...........(..).................................................................................................... >AACY020177622.1/1062-1175 GGUCAUGAGUCUCAGUUCAUAGCCCCGGCUAACUGAGCGGCAACCCUCCACCACGGUGGGGUGCUCCGGGUGAAGACCAGGUUGAUUGCAAAGUGCAAUCAGCAAGCGUGGGUC .......................(..)....................................................................................... >CP000454.1/2980407-2980520 GGUCACGAGUGCCAGCGCUAAACCCCGGUUUGCUGGCCGGCAACCCUCCAUUCGCGGUGGGGUGCCCCGGGUGACGACCAGGCCGGUCCGGAACGGACCCGGCAAGCGCGGAUC .......................(..)....................................................................................... >CP000480.1/1748393-1748264 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUGGUUGACGGAUUCCUCCGUCGGCCGCAAGGCAAGCGCGGGUC .......................(..)....................................................................................................... >AP006618.1/396893-397006 GGUCAUGAGUGCCAGCGCAAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGCCGCCGUCCGACCGGACGCGGCAAGCGCGGACU ...........(..)................................................................................................... >BA000030.3/8585292-8585400 GGUCAAGAGCGUCAGCGACAAGCCCUGGCUUGCUGACCGGCAACCCUCGCGACGCGGUGGGGUGCCCCAGGUGACGACCGGACCGGAUGACCUUCGGUAAGCGCGAGGC .......................(..).................................................................................. >AAMN01000002.1/91115-91229 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAAGACCAGGCGGAGCGUCGACCGGCGCCCGCAAGCACGGCAU .......................(..)........................................................................................ >AE016958.1/3838572-3838694 GGUCAUGAGCGCCAGCAUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACCACAACCGGCUAUCCGGCAAGCGCGGGUC .......................(..)................................................................................................ >CP000750.2/1351757-1351870 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGACGACCUGGCCGGUGCCGACGUGGCGCCGGCAAGCGCGGACC .......................(..)....................................................................................... >AAAP01003574.1/1814-1929 GGUCAUGAGUGCCAGCGCGAAACCCCGGUUUGCUGGCCGGCAACCCUCCUCUCGCGGCGGGGUGCCCCGGGUGACGACCAGGCCGCACGCCGACCGGCGGGCGGCAAGCGCGGGGA ...........(..)..................................................................................................... >CP000431.1/4627893-4628007 GGUCACGAGUACCAGCGUCAAGCCCCGGCUAGCUGGUCGGCAACCCUCCACCGCGGCGGGGUGCUCCGGGUGACGACCAGGCUGAGGUCCAUACCGGACCCGGCAAGCGCGGACU .......................(..)........................................................................................ >CP000580.1/914360-914249 GCUCACGAGCGGACGGCAGUUUGGGUACCUGGCCCGUCGUCCCGGCAACCGCGCGACCACCGCACGGUGCCCCAGGGGAAGAGCGGGCGCGGCUUACGUGCAAGUGGUGGAC .......................................................................(..)..................................... >CP000518.1/928910-928799 GCUCACGAGCGGACGACUGUUCGGGUACCUGGCCCGUCGUCCCGGCAACCGCGCGACCGCCGCACGGUGCCCCAGGGGAAGAGCGGGCACGAGCAUCGUGCAAGUGGUGGAC .......................................................................(..)..................................... >CP000454.1/1479286-1479401 GGUCAUGAGUGCCAGCGACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUUCGCGGCGGGGUGCCCCGGGUGAAGACCUGGCCUGCCGGCCAGUUGGCGGCAGGCAAGCGCGAAGA ......................(..).......................................................................................... >AF052077.1/1481-1597 GGUCAUGAGUGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUGGACAGCAAGGUCCACGGCAAGCGCGGAUC ........................(..).........................................................................................
2		C(CN)G ((G)C)G			29	72.5
>CP000325.1/1553430-1553311 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGUCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACAGUCGGCUACACGGCAAGCGCGGGUC .......................(..)...................((.....).)................................................................ >AAMN01000002.1/91115-91229 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAAGACCAGGCGGAGCGUCGACCGGCGCCCGCAAGCACGGCAU .......................(..)....................((....).)........................................................... >AAAP01003574.1/1814-1929 GGUCAUGAGUGCCAGCGCGAAACCCCGGUUUGCUGGCCGGCAACCCUCCUCUCGCGGCGGGGUGCCCCGGGUGACGACCAGGCCGCACGCCGACCGGCGGGCGGCAAGCGCGGGGA ...........(..)..............................(.(.....).)............................................................ >CP000480.1/1748393-1748264 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUGGUUGACGGAUUCCUCCGUCGGCCGCAAGGCAAGCGCGGGUC .......................(..)....................((....).).......................................................................... >CT573213.2/4831346-4831458 UGUCACGAGUGCCAACGUCCAGCCCCGGCUUGUUGGCCGGCAACCCUCCACCGCGAAGGGGUGCCCCGGGUGAGGACACGGCCGCAUCCAGUGGAGGCGGCAAAGCGCGGGCC .......................(..)....................((...).).......................................................... >CP000454.1/1479286-1479401 GGUCAUGAGUGCCAGCGACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUUCGCGGCGGGGUGCCCCGGGUGAAGACCUGGCCUGCCGGCCAGUUGGCGGCAGGCAAGCGCGAAGA ......................(..)....................((....).)............................................................. >AM420293.1/6539181-6539066 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAGGACCUGGCCGGUCGCGCAGGGCGACCCGGCAAGCGCGGGCC .......................(..)....................((....).)............................................................ >CP000656.1/5531569-5531680 GCUCACGAGCGGACGACUGUUCGGGUACCUGGCCCGUCGUCCCGGCAACCGCGCGACCACCGCACGGUGCCCCAGGGGAAGAGCGGGCACGCGGUGCGUGCAAGCGGUGGAC .......................................................................(..)..............(.(...........).)...... >CP000454.1/2980407-2980520 GGUCACGAGUGCCAGCGCUAAACCCCGGUUUGCUGGCCGGCAACCCUCCAUUCGCGGUGGGGUGCCCCGGGUGACGACCAGGCCGGUCCGGAACGGACCCGGCAAGCGCGGAUC .......................(..).....................((...).).......................................................... >CP000431.1/6724422-6724302 GGUCAUGAGUGCCAGCAACGAGCCCCGGCUAGCUGGCCGGCAACCCUCCACCGCGGUGGGGUGCCCCGGGUGAUGACCUGGUUUCCUGAUUCACACAACAGUCGGGUGACAAGCGCGGGUC .......................(..)....................((...).).................................................................. >AE016958.1/3838572-3838694 GGUCAUGAGCGCCAGCAUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACCACAACCGGCUAUCCGGCAAGCGCGGGUC .......................(..).................((.......).)................................................................... >CP000750.2/3280159-3280049 GGUCAUGAGUGACAGCGACAAGCCCUGGCUCGCUGUCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCAGGUGAAGACCCGGCCGGACGAAAACGUCCGGCAAGCGCGGAUC .......................(..)...................((.......).)..................................................... >CT573213.2/4609200-4609314 CGUCUUGAGUGCCAGCGUUCAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUAUGCAGCGGGGUGCCCCGGGUGGUGACGAGGCCGCGGCAACCCCGCCGACGGCAAGUGCCGACC ...........(..).............................((..........).)........................................................ >AAMN01000002.1/4575-4689 GGUCACGAGUACCAGUGUUCAGCCCCGGCUUGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGUCGGCUGCAGCAACGCAGUUGGCAAGCGCGGACU ...........(..)................................((...).)............................................................ >CP000511.1/1643745-1643626 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGGCCACGGCUAUAAGGCAAGCGCGGGUC .......................(..).....................((...).)................................................................ >AF052077.1/1481-1597 GGUCAUGAGUGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUGGACAGCAAGGUCCACGGCAAGCGCGGAUC ........................(..)...................((........).)......................................................... >CP000611.1/3736812-3736931 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCAUCGCCGGCUGCGCGGCAAGCGCGGGUC .......................(..)....................((....).)................................................................ >CP000667.1/317960-317841 GGUCACGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCGUCGAGGUUCGCGGUGGGGUGCCCCGGGUGAUGACCGGGCCUGGCGCGGCGCGCGUCGGGCAAGCGCGGACC .......................(..)....................(..(.......).)........................................................... >CP000820.1/5910611-5910498 GGUCCUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCUCCGCGGUGGGGUGCCCCGGGUGUGACCAGGCCCGCGGCGAACCCGCCGUCGGCAAGUGCGGACC ...........(..)................................((...).)........................................................... >BA000030.3/7291233-7291349 GGUCAUGAGCGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUAGGCAGCGAGGUCUACGGCAAGCGCGGACC ........................(..)...................((........).)......................................................... >CP000474.1/2904762-2904875 GGUCACGAGUGCCAGCGCUAAACCCCGGUUUGCUGGCCGGCAACCCUCCAUUCGCGGUGGGGUGCCCCGGGUGACGACCCGGCCGGUCCGGAAUGGAUGCGGCAAGCGCGGAUC .......................(..).....................((...).).......................................................... >CP000474.1/1618337-1618453 GGUCAUGAGUGCCAGCACACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUCCGCGGUGGGGUGCCCCGGGUGAAGACCUGGCCUGUUCGCACGCAAGGCGACGGGCAAGCGCGAGGU ...........(..)................................((...).).............................................................. >BA000030.3/8585292-8585400 GGUCAAGAGCGUCAGCGACAAGCCCUGGCUUGCUGACCGGCAACCCUCGCGACGCGGUGGGGUGCCCCAGGUGACGACCGGACCGGAUGACCUUCGGUAAGCGCGAGGC .......................(..)...................((.....).)..................................................... >CP000750.2/1351757-1351870 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGACGACCUGGCCGGUGCCGACGUGGCGCCGGCAAGCGCGGACC .......................(..)...................((.......).)........................................................ >CP000509.1/3644126-3644238 CGUCACGAGUACUGGCGCGAAGCCCCGGCUGGCCAGUCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGAGGACACGGCCGACUGCGACCGCAGCCGGCAAGCGCGGACU .......................(..)..................(.(.......).)....................................................... >AP006618.1/396893-397006 GGUCAUGAGUGCCAGCGCAAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGCCGCCGUCCGACCGGACGCGGCAAGCGCGGACU ...........(..)...............................((....).)........................................................... >CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC .......................(..)...................((.....).)............................................................... >AP006618.1/5665640-5665528 GGUCAUGAGCACCAGCGCCAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGCGGGGUGCUCCGGGUGACGACCUGGCCGUACCGAAGACGGUGCGGCAAGUGCGGAUU .......................(..)...................((.......).)....................................................... >CP000431.1/4627893-4628007 GGUCACGAGUACCAGCGUCAAGCCCCGGCUAGCUGGUCGGCAACCCUCCACCGCGGCGGGGUGCUCCGGGUGACGACCAGGCUGAGGUCCAUACCGGACCCGGCAAGCGCGGACU .......................(..).....................(.(....).).........................................................
3		C(CN)G ((G)C)G (()()(R)N)G			21	52.5
>CT573213.2/4831346-4831458 UGUCACGAGUGCCAACGUCCAGCCCCGGCUUGUUGGCCGGCAACCCUCCACCGCGAAGGGGUGCCCCGGGUGAGGACACGGCCGCAUCCAGUGGAGGCGGCAAAGCGCGGGCC .........((............(..).........)(.........((...).)......................)(.......................).)........ >CP000454.1/1479286-1479401 GGUCAUGAGUGCCAGCGACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUUCGCGGCGGGGUGCCCCGGGUGAAGACCUGGCCUGCCGGCCAGUUGGCGGCAGGCAAGCGCGAAGA .......((.............(..)..........)(........((....).).....................)(.............................).)...... >AE016958.1/3838572-3838694 GGUCAUGAGCGCCAGCAUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACCACAACCGGCUAUCCGGCAAGCGCGGGUC .........((............(..).........)(......((.......).)......................).(...............................).)........ >CP000325.1/1553430-1553311 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGUCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACAGUCGGCUACACGGCAAGCGCGGGUC .........((............(..).........)(........((.....).)......................).(............................).)........ >BA000030.3/8585292-8585400 GGUCAAGAGCGUCAGCGACAAGCCCUGGCUUGCUGACCGGCAACCCUCGCGACGCGGUGGGGUGCCCCAGGUGACGACCGGACCGGAUGACCUUCGGUAAGCGCGAGGC .........((............(..).........).(.......((.....).)..................)(......................).)........ >AP006618.1/396893-397006 GGUCAUGAGUGCCAGCGCAAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGCCGCCGUCCGACCGGACGCGGCAAGCGCGGACU ...((......(..)..................).(..........((....).).....................)(...........................).)...... >AAMN01000002.1/4575-4689 GGUCACGAGUACCAGUGUUCAGCCCCGGCUUGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGUCGGCUGCAGCAACGCAGUUGGCAAGCGCGGACU .....((....(..)...................)(...........((...).).....................)(............................).)...... >AF052077.1/1481-1597 GGUCAUGAGUGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUGGACAGCAAGGUCCACGGCAAGCGCGGAUC .......(..(.............(..).........).(.......((........).)..................)(............................).)...... >CP000431.1/4627893-4628007 GGUCACGAGUACCAGCGUCAAGCCCCGGCUAGCUGGUCGGCAACCCUCCACCGCGGCGGGGUGCUCCGGGUGACGACCAGGCUGAGGUCCAUACCGGACCCGGCAAGCGCGGACU .......((..............(..).....)(..............(.(....).)....................)(........................).)........ >AM420293.1/6539181-6539066 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAGGACCUGGCCGGUCGCGCAGGGCGACCCGGCAAGCGCGGGCC .......((..............(..)..........)(........((....).).....................)(............................).)...... >CP000750.2/3280159-3280049 GGUCAUGAGUGACAGCGACAAGCCCUGGCUCGCUGUCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCAGGUGAAGACCCGGCCGGACGAAAACGUCCGGCAAGCGCGGAUC ....(...(..............(..)..........)(.......((.......).)..................)(..........................).).... >BA000030.3/7291233-7291349 GGUCAUGAGCGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUAGGCAGCGAGGUCUACGGCAAGCGCGGACC .........((.............(..).........).(.......((........).)..................)(............................).)...... >CP000750.2/1351757-1351870 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGACGACCUGGCCGGUGCCGACGUGGCGCCGGCAAGCGCGGACC .......((..............(..)..........)(.......((.......).)..................)(...........................).)...... >CP000431.1/6724422-6724302 GGUCAUGAGUGCCAGCAACGAGCCCCGGCUAGCUGGCCGGCAACCCUCCACCGCGGUGGGGUGCCCCGGGUGAUGACCUGGUUUCCUGAUUCACACAACAGUCGGGUGACAAGCGCGGGUC .........((............(..).........).(........((...).)......................).(..............................).)........ >AAMN01000002.1/91115-91229 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAAGACCAGGCGGAGCGUCGACCGGCGCCCGCAAGCACGGCAU .......((..............(..)..........)(........((....).).....................).(........................).)........ >CP000611.1/3736812-3736931 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCAUCGCCGGCUGCGCGGCAAGCGCGGGUC .........((............(..).........).(........((....).).....................)..(............................).)........ >CP000509.1/3644126-3644238 CGUCACGAGUACUGGCGCGAAGCCCCGGCUGGCCAGUCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGAGGACACGGCCGACUGCGACCGCAGCCGGCAAGCGCGGACU .........((............(..).........).(......(.(.......).)..................)(........................).)........ >CP000511.1/1643745-1643626 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGGCCACGGCUAUAAGGCAAGCGCGGGUC .........((............(..).........).(.........((...).).......................)(............................).)........ >CP000667.1/317960-317841 GGUCACGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCGUCGAGGUUCGCGGUGGGGUGCCCCGGGUGAUGACCGGGCCUGGCGCGGCGCGCGUCGGGCAAGCGCGGACC .......(..(............(..).........).(........(..(.......).).....................)(...........................).)...... >AP006618.1/5665640-5665528 GGUCAUGAGCACCAGCGCCAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGCGGGGUGCUCCGGGUGACGACCUGGCCGUACCGAAGACGGUGCGGCAAGUGCGGAUU ....(......(...........(..)........)(.........((.......).).................)(.............................).).... >CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC .........((............(..).........)(........((.....).)......................)(............................).)........
4		C(CN)G ((G)C)G (()()(R)N)G G(UG)C			17	42.5
>CP000454.1/1479286-1479401 GGUCAUGAGUGCCAGCGACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUUCGCGGCGGGGUGCCCCGGGUGAAGACCUGGCCUGCCGGCCAGUUGGCGGCAGGCAAGCGCGAAGA .......((.............(..)..........)(........((....).).....(..)............)(.............................).)...... >CP000667.1/317960-317841 GGUCACGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCGUCGAGGUUCGCGGUGGGGUGCCCCGGGUGAUGACCGGGCCUGGCGCGGCGCGCGUCGGGCAAGCGCGGACC .......(..(............(..).........).(........(..(.......).).....(..)............)(...........................).)...... >BA000030.3/7291233-7291349 GGUCAUGAGCGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUAGGCAGCGAGGUCUACGGCAAGCGCGGACC .........((.............(..).........).(.......((........).)..(..)............)(............................).)...... >AF052077.1/1481-1597 GGUCAUGAGUGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUGGACAGCAAGGUCCACGGCAAGCGCGGAUC .......(..(.............(..).........).(.......((........).)..(..)............)(............................).)...... >CP000750.2/3280159-3280049 GGUCAUGAGUGACAGCGACAAGCCCUGGCUCGCUGUCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCAGGUGAAGACCCGGCCGGACGAAAACGUCCGGCAAGCGCGGAUC ....(...(..............(..)..........)(.......((.......).)..(..)............)(..........................).).... >CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC .........((............(..).........)(........((.....).).....(..).............)(............................).)........ >CT573213.2/4831346-4831458 UGUCACGAGUGCCAACGUCCAGCCCCGGCUUGUUGGCCGGCAACCCUCCACCGCGAAGGGGUGCCCCGGGUGAGGACACGGCCGCAUCCAGUGGAGGCGGCAAAGCGCGGGCC .........((............(..).........)(.........((...).).....(..).............)(.......................).)........ >AAMN01000002.1/91115-91229 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAAGACCAGGCGGAGCGUCGACCGGCGCCCGCAAGCACGGCAU .......((..............(..)..........)(........((....).).....(..)............).(........................).)........ >CP000750.2/1351757-1351870 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGACGACCUGGCCGGUGCCGACGUGGCGCCGGCAAGCGCGGACC .......((..............(..)..........)(.......((.......).)..(..)............)(...........................).)...... >AM420293.1/6539181-6539066 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAGGACCUGGCCGGUCGCGCAGGGCGACCCGGCAAGCGCGGGCC .......((..............(..)..........)(........((....).).....(..)............)(............................).)...... >AE016958.1/3838572-3838694 GGUCAUGAGCGCCAGCAUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACCACAACCGGCUAUCCGGCAAGCGCGGGUC .........((............(..).........)(......((.......).).....(..).............).(...............................).)........ >AP006618.1/5665640-5665528 GGUCAUGAGCACCAGCGCCAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGCGGGGUGCUCCGGGUGACGACCUGGCCGUACCGAAGACGGUGCGGCAAGUGCGGAUU ....(......(...........(..)........)(.........((.......).)..(..)...........)(.............................).).... >CP000431.1/6724422-6724302 GGUCAUGAGUGCCAGCAACGAGCCCCGGCUAGCUGGCCGGCAACCCUCCACCGCGGUGGGGUGCCCCGGGUGAUGACCUGGUUUCCUGAUUCACACAACAGUCGGGUGACAAGCGCGGGUC .........((............(..).........).(........((...).).....(..).............).(..............................).)........ >CP000611.1/3736812-3736931 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCAUCGCCGGCUGCGCGGCAAGCGCGGGUC .........((............(..).........).(........((....).).....(..)............)..(............................).)........ >CP000325.1/1553430-1553311 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGUCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACAGUCGGCUACACGGCAAGCGCGGGUC .........((............(..).........)(........((.....).).....(..).............).(............................).)........ >CP000509.1/3644126-3644238 CGUCACGAGUACUGGCGCGAAGCCCCGGCUGGCCAGUCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGAGGACACGGCCGACUGCGACCGCAGCCGGCAAGCGCGGACU .........((............(..).........).(......(.(.......).)..(..)............)(........................).)........ >CP000511.1/1643745-1643626 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGGCCACGGCUAUAAGGCAAGCGCGGGUC .........((............(..).........).(.........((...).).....(..)..............)(............................).)........
5		C(CN)G ((G)C)G (()()(R)N)G G(UG)C (.GNN.().N.)			14	35.0
>CP000611.1/3736812-3736931 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCAUCGCCGGCUGCGCGGCAAGCGCGGGUC .........((....(....(..(..)..).)....)(..........((...).).....(..)..............)(............................).)........ >CP000511.1/1643745-1643626 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGGCCACGGCUAUAAGGCAAGCGCGGGUC .........((....(....(..(..)..).)....).(.........((...).).....(..)..............)(............................).)........ >AF052077.1/1481-1597 GGUCAUGAGUGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUGGACAGCAAGGUCCACGGCAAGCGCGGAUC .......(..(.....(.....(.(..).).).....).(.......((........).)..(..)............)(............................).)...... >BA000030.3/7291233-7291349 GGUCAUGAGCGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUAGGCAGCGAGGUCUACGGCAAGCGCGGACC .........((.....(.....(.(..).).).....).(.......((........).)..(..)............)(............................).)...... >AM420293.1/6539181-6539066 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAGGACCUGGCCGGUCGCGCAGGGCGACCCGGCAAGCGCGGGCC .......((......(....(..(..)..).).....)(........((....).).....(..)............)(............................).)...... >CP000509.1/3644126-3644238 CGUCACGAGUACUGGCGCGAAGCCCCGGCUGGCCAGUCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGAGGACACGGCCGACUGCGACCGCAGCCGGCAAGCGCGGACU .........((....(....(..(..)..).)....).(......(.(.......).)..(..)............)(........................).)........ >CP000325.1/1553430-1553311 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGUCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACAGUCGGCUACACGGCAAGCGCGGGUC .........((....(....(..(..)..).)....)(.........((....).).....(..).............).(............................).)........ >CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC .........((....(....(..(..)..).)....)(........((.....).).....(..).............)(............................).)........ >AP006618.1/5665640-5665528 GGUCAUGAGCACCAGCGCCAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGCGGGGUGCUCCGGGUGACGACCUGGCCGUACCGAAGACGGUGCGGCAAGUGCGGAUU ....(......(...(....(..(..)..).)...)(.........((.......).)..(..)...........)(.............................).).... >CP000750.2/1351757-1351870 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGACGACCUGGCCGGUGCCGACGUGGCGCCGGCAAGCGCGGACC .......((......(....(..(..)..).).....)(.......((.......).)..(..)............)(...........................).)...... >CP000454.1/1479286-1479401 GGUCAUGAGUGCCAGCGACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUUCGCGGCGGGGUGCCCCGGGUGAAGACCUGGCCUGCCGGCCAGUUGGCGGCAGGCAAGCGCGAAGA .......((......(...(..(..)..).).....)(........((....).).....(..)............)(.............................).)...... >CP000750.2/3280159-3280049 GGUCAUGAGUGACAGCGACAAGCCCUGGCUCGCUGUCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCAGGUGAAGACCCGGCCGGACGAAAACGUCCGGCAAGCGCGGAUC ....(...(......(....(..(..)..).).....)(.......((.......).)..(..)............)(..........................).).... >AAMN01000002.1/91115-91229 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAAGACCAGGCGGAGCGUCGACCGGCGCCCGCAAGCACGGCAU .......((......(....(..(..)..).).....)(........((....).).....(..)............).(........................).)........ >CP000667.1/317960-317841 GGUCACGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCGUCGAGGUUCGCGGUGGGGUGCCCCGGGUGAUGACCGGGCCUGGCGCGGCGCGCGUCGGGCAAGCGCGGACC .......(..(....(....(..(..)..).)....).(........(..(.......).).....(..)............)(...........................).)......

>CP000509.1/3644126-3644238 CGUCACGAGUACUGGCGCGAAGCCCCGGCUGGCCAGUCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGAGGACACGGCCGACUGCGACCGCAGCCGGCAAGCGCGGACU .......................(..)...................................................................................... .......................(..)..................(.(.......).)....................................................... .........((............(..).........).(......(.(.......).)..................)(........................).)........ .........((............(..).........).(......(.(.......).)..(..)............)(........................).)........ .........((....(....(..(..)..).)....).(......(.(.......).)..(..)............)(........................).)........ >CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC .......................(..)............................................................................................ .......................(..)...................((.....).)............................................................... .........((............(..).........)(........((.....).)......................)(............................).)........ .........((............(..).........)(........((.....).).....(..).............)(............................).)........ .........((....(....(..(..)..).)....)(........((.....).).....(..).............)(............................).)........ >BA000030.3/7291233-7291349 GGUCAUGAGCGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUAGGCAGCGAGGUCUACGGCAAGCGCGGACC ........................(..)......................................................................................... ........................(..)...................((........).)......................................................... .........((.............(..).........).(.......((........).)..................)(............................).)...... .........((.............(..).........).(.......((........).)..(..)............)(............................).)...... .........((.....(.....(.(..).).).....).(.......((........).)..(..)............)(............................).)...... >CP000750.2/3280159-3280049 GGUCAUGAGUGACAGCGACAAGCCCUGGCUCGCUGUCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCAGGUGAAGACCCGGCCGGACGAAAACGUCCGGCAAGCGCGGAUC .......................(..).................................................................................... .......................(..)...................((.......).)..................................................... ....(...(..............(..)..........)(.......((.......).)..................)(..........................).).... ....(...(..............(..)..........)(.......((.......).)..(..)............)(..........................).).... ....(...(......(....(..(..)..).).....)(.......((.......).)..(..)............)(..........................).).... >AM420293.1/6539181-6539066 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAGGACCUGGCCGGUCGCGCAGGGCGACCCGGCAAGCGCGGGCC .......................(..)......................................................................................... .......................(..)....................((....).)............................................................ .......((..............(..)..........)(........((....).).....................)(............................).)...... .......((..............(..)..........)(........((....).).....(..)............)(............................).)...... .......((......(....(..(..)..).).....)(........((....).).....(..)............)(............................).)...... >CP000511.1/1643745-1643626 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGGCCACGGCUAUAAGGCAAGCGCGGGUC .......................(..)............................................................................................. .......................(..).....................((...).)................................................................ .........((............(..).........).(.........((...).).......................)(............................).)........ .........((............(..).........).(.........((...).).....(..)..............)(............................).)........ .........((....(....(..(..)..).)....).(.........((...).).....(..)..............)(............................).)........ >AP006618.1/5665640-5665528 GGUCAUGAGCACCAGCGCCAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGCGGGGUGCUCCGGGUGACGACCUGGCCGUACCGAAGACGGUGCGGCAAGUGCGGAUU .......................(..)...................................................................................... .......................(..)...................((.......).)....................................................... ....(......(...........(..)........)(.........((.......).).................)(.............................).).... ....(......(...........(..)........)(.........((.......).)..(..)...........)(.............................).).... ....(......(...(....(..(..)..).)...)(.........((.......).)..(..)...........)(.............................).).... >CP000611.1/3736812-3736931 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCAUCGCCGGCUGCGCGGCAAGCGCGGGUC .......................(..)............................................................................................. .......................(..)....................((....).)................................................................ .........((............(..).........).(........((....).).....................)..(............................).)........ .........((............(..).........).(........((....).).....(..)............)..(............................).)........ .........((....(....(..(..)..).)....)(..........((...).).....(..)..............)(............................).)........ >CP000325.1/1553430-1553311 GGUCAUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGUCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACAGUCGGCUACACGGCAAGCGCGGGUC .......................(..)............................................................................................. .......................(..)...................((.....).)................................................................ .........((............(..).........)(........((.....).)......................).(............................).)........ .........((............(..).........)(........((.....).).....(..).............).(............................).)........ .........((....(....(..(..)..).)....)(.........((....).).....(..).............).(............................).)........ >CP000667.1/317960-317841 GGUCACGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCGUCGAGGUUCGCGGUGGGGUGCCCCGGGUGAUGACCGGGCCUGGCGCGGCGCGCGUCGGGCAAGCGCGGACC .......................(..)............................................................................................. .......................(..)....................(..(.......).)........................................................... .......(..(............(..).........).(........(..(.......).).....................)(...........................).)...... .......(..(............(..).........).(........(..(.......).).....(..)............)(...........................).)...... .......(..(....(....(..(..)..).)....).(........(..(.......).).....(..)............)(...........................).)...... >AAMN01000002.1/91115-91229 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAAGACCAGGCGGAGCGUCGACCGGCGCCCGCAAGCACGGCAU .......................(..)........................................................................................ .......................(..)....................((....).)........................................................... .......((..............(..)..........)(........((....).).....................).(........................).)........ .......((..............(..)..........)(........((....).).....(..)............).(........................).)........ .......((......(....(..(..)..).).....)(........((....).).....(..)............).(........................).)........ >CP000750.2/1351757-1351870 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUCGCUGGCCGGCAACCCUCCUCCGCGGCGGGGUGCCCCGGGUGACGACCUGGCCGGUGCCGACGUGGCGCCGGCAAGCGCGGACC .......................(..)....................................................................................... .......................(..)...................((.......).)........................................................ .......((..............(..)..........)(.......((.......).)..................)(...........................).)...... .......((..............(..)..........)(.......((.......).)..(..)............)(...........................).)...... .......((......(....(..(..)..).).....)(.......((.......).)..(..)............)(...........................).)...... >CP000454.1/1479286-1479401 GGUCAUGAGUGCCAGCGACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUUCGCGGCGGGGUGCCCCGGGUGAAGACCUGGCCUGCCGGCCAGUUGGCGGCAGGCAAGCGCGAAGA ......................(..).......................................................................................... ......................(..)....................((....).)............................................................. .......((.............(..)..........)(........((....).).....................)(.............................).)...... .......((.............(..)..........)(........((....).).....(..)............)(.............................).)...... .......((......(...(..(..)..).).....)(........((....).).....(..)............)(.............................).)...... >AF052077.1/1481-1597 GGUCAUGAGUGACAGUCAUGAGGCCCCGGCCGACUGUCCGGCAACCCUCCGUCCGUGGCGGGGUGCCCCGGGUGAAGACCAGGUCGUGGACAGCAAGGUCCACGGCAAGCGCGGAUC ........................(..)......................................................................................... ........................(..)...................((........).)......................................................... .......(..(.............(..).........).(.......((........).)..................)(............................).)...... .......(..(.............(..).........).(.......((........).)..(..)............)(............................).)...... .......(..(.....(.....(.(..).).).....).(.......((........).)..(..)............)(............................).)...... >CT573213.2/4831346-4831458 UGUCACGAGUGCCAACGUCCAGCCCCGGCUUGUUGGCCGGCAACCCUCCACCGCGAAGGGGUGCCCCGGGUGAGGACACGGCCGCAUCCAGUGGAGGCGGCAAAGCGCGGGCC .......................(..)...................................................................................... .......................(..)....................((...).).......................................................... .........((............(..).........)(.........((...).)......................)(.......................).)........ .........((............(..).........)(.........((...).).....(..).............)(.......................).)........ >CP000431.1/6724422-6724302 GGUCAUGAGUGCCAGCAACGAGCCCCGGCUAGCUGGCCGGCAACCCUCCACCGCGGUGGGGUGCCCCGGGUGAUGACCUGGUUUCCUGAUUCACACAACAGUCGGGUGACAAGCGCGGGUC .......................(..).............................................................................................. .......................(..)....................((...).).................................................................. .........((............(..).........).(........((...).)......................).(..............................).)........ .........((............(..).........).(........((...).).....(..).............).(..............................).)........ >AE016958.1/3838572-3838694 GGUCAUGAGCGCCAGCAUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCACCACAACCGGCUAUCCGGCAAGCGCGGGUC .......................(..)................................................................................................ .......................(..).................((.......).)................................................................... .........((............(..).........)(......((.......).)......................).(...............................).)........ .........((............(..).........)(......((.......).).....(..).............).(...............................).)........ >AAMN01000002.1/4575-4689 GGUCACGAGUACCAGUGUUCAGCCCCGGCUUGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGUCGGCUGCAGCAACGCAGUUGGCAAGCGCGGACU ...........(..).................................................................................................... ...........(..)................................((...).)............................................................ .....((....(..)...................)(...........((...).).....................)(............................).)...... >AP006618.1/396893-397006 GGUCAUGAGUGCCAGCGCAAAGCCCCGGCUCGCUGGUCGGCAACCCUCCUCCGCGGUGGGGUGCUCCGGGUGACGACCUGGCCGCCGUCCGACCGGACGCGGCAAGCGCGGACU ...........(..)................................................................................................... ...........(..)...............................((....).)........................................................... ...((......(..)..................).(..........((....).).....................)(...........................).)...... >BA000030.3/8585292-8585400 GGUCAAGAGCGUCAGCGACAAGCCCUGGCUUGCUGACCGGCAACCCUCGCGACGCGGUGGGGUGCCCCAGGUGACGACCGGACCGGAUGACCUUCGGUAAGCGCGAGGC .......................(..).................................................................................. .......................(..)...................((.....).)..................................................... .........((............(..).........).(.......((.....).)..................)(......................).)........ >CP000431.1/4627893-4628007 GGUCACGAGUACCAGCGUCAAGCCCCGGCUAGCUGGUCGGCAACCCUCCACCGCGGCGGGGUGCUCCGGGUGACGACCAGGCUGAGGUCCAUACCGGACCCGGCAAGCGCGGACU .......................(..)........................................................................................ .......................(..).....................(.(....).)......................................................... .......((..............(..).....)(..............(.(....).)....................)(........................).)........ >CP000820.1/5910611-5910498 GGUCCUGAGCGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCUCCGCGGUGGGGUGCCCCGGGUGUGACCAGGCCCGCGGCGAACCCGCCGUCGGCAAGUGCGGACC ...........(..)................................................................................................... ...........(..)................................((...).)........................................................... >CP000656.1/5531569-5531680 GCUCACGAGCGGACGACUGUUCGGGUACCUGGCCCGUCGUCCCGGCAACCGCGCGACCACCGCACGGUGCCCCAGGGGAAGAGCGGGCACGCGGUGCGUGCAAGCGGUGGAC .......................................................................(..)..................................... .......................................................................(..)..............(.(...........).)...... >CP000474.1/2904762-2904875 GGUCACGAGUGCCAGCGCUAAACCCCGGUUUGCUGGCCGGCAACCCUCCAUUCGCGGUGGGGUGCCCCGGGUGACGACCCGGCCGGUCCGGAAUGGAUGCGGCAAGCGCGGAUC .......................(..)....................................................................................... .......................(..).....................((...).).......................................................... >CP000474.1/1618337-1618453 GGUCAUGAGUGCCAGCACACAGCCCCGGCUUGCUGGCCGGCAACCCUCCUCCGCGGUGGGGUGCCCCGGGUGAAGACCUGGCCUGUUCGCACGCAAGGCGACGGGCAAGCGCGAGGU ...........(..)...................................................................................................... ...........(..)................................((...).).............................................................. >CT573213.2/4609200-4609314 CGUCUUGAGUGCCAGCGUUCAGCCCCGGCUUGCUGGCCGGCAACCCUCCUUAUGCAGCGGGGUGCCCCGGGUGGUGACGAGGCCGCGGCAACCCCGCCGACGGCAAGUGCCGACC ...........(..).................................................................................................... ...........(..).............................((..........).)........................................................ >CP000454.1/2980407-2980520 GGUCACGAGUGCCAGCGCUAAACCCCGGUUUGCUGGCCGGCAACCCUCCAUUCGCGGUGGGGUGCCCCGGGUGACGACCAGGCCGGUCCGGAACGGACCCGGCAAGCGCGGAUC .......................(..)....................................................................................... .......................(..).....................((...).).......................................................... >CP000480.1/1748393-1748264 GGUCAUGAGCGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUGGUUGACGGAUUCCUCCGUCGGCCGCAAGGCAAGCGCGGGUC .......................(..)....................................................................................................... .......................(..)....................((....).).......................................................................... >AAAP01003574.1/1814-1929 GGUCAUGAGUGCCAGCGCGAAACCCCGGUUUGCUGGCCGGCAACCCUCCUCUCGCGGCGGGGUGCCCCGGGUGACGACCAGGCCGCACGCCGACCGGCGGGCGGCAAGCGCGGGGA ...........(..)..................................................................................................... ...........(..)..............................(.(.....).)............................................................ >AAGP01000018.1/74571-74460 GUUCACGAGUCGUGGCUAUCGGUACCUGGCCGGCCACGCGGCAACCCGUCAUCGACCGGGUGCCCCAGGGAAAGAACGGGCCCGCACCACGUGGUGCUGGCAAGAUUCGAUC .............................(..)............................................................................... >CP000656.1/5194683-5194802 GGUCAUGAGUGCCAGCGACAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGAGACGACCAGGUUGAGUAGCCGAACACGGCUAUAAGGCAAGCGCGGGUC .......................(..)............................................................................................. >AACY020524451.1/3761-3655 GGUCAUGAGUGCCAGCGAUAAGCCCCGGCUUGCUGGCCGGCAACCCUCCGACCGCGGUGGGGUGCUCCGGGUGAAGACCAGGCCUGAUAGUCAGGCAAGCGCGGGUC .......................(..)................................................................................ >CP000480.1/1361993-1361882 CUUCACGAGACGCCGUCGACAAGCUCCGACUGGAUGGCGCGCCAACCCCACGCUCGUGGGUGGCUCGGAUGACGAAGCGGCCUGCACCACCCGGUGCGGGUAAGAGCGCCUC .........................................................................................(..)................... >U00022.1/34579-34697 GGUCAUGAGCGCCAGCGUCAAGCCCCGACUUGCUGGCCGGCAACCCUCCAACCGCGUUGGAGUGCCCCGGUGAUGACCAGGUUGAGUAGCCAGAACCGGCUACGCGGCAAGCGCGAGUC .................................................................(..).................................................. >AACY020177622.1/1062-1175 GGUCAUGAGUCUCAGUUCAUAGCCCCGGCUAACUGAGCGGCAACCCUCCACCACGGUGGGGUGCUCCGGGUGAAGACCAGGUUGAUUGCAAAGUGCAAUCAGCAAGCGUGGGUC .......................(..)....................................................................................... >CP000580.1/914360-914249 GCUCACGAGCGGACGGCAGUUUGGGUACCUGGCCCGUCGUCCCGGCAACCGCGCGACCACCGCACGGUGCCCCAGGGGAAGAGCGGGCGCGGCUUACGUGCAAGUGGUGGAC .......................................................................(..)..................................... >CP000518.1/928910-928799 GCUCACGAGCGGACGACUGUUCGGGUACCUGGCCCGUCGUCCCGGCAACCGCGCGACCGCCGCACGGUGCCCCAGGGGAAGAGCGGGCACGAGCAUCGUGCAAGUGGUGGAC .......................................................................(..).....................................

	ORB			p-value	ORB frequency (per structure per nucleotide)	Means ratio
1	C(CN)G			< 0.001		8.63

CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC ...................................................................................................1................... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1......... 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
2	((G)C)G			< 0.001		2.82

CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC ...................................................................................................1................... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1......... 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
3	(()()(R)N)G			< 0.001		8.15

CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC ...................................................................................................1................... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1......... 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
4	G(UG)C			< 0.001		18.9

CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC ...................................................................................................1................... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1......... 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
5	(.GNN.().N.)			< 0.001		1.33

CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC ...................................................................................................1................... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1......... 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
	ORB			p-value	ORB frequency (per structure per nucleotide)	Means ratio

	NCM			p-value	NCM frequency (per structure per nucleotide)	Means ratio
1	(CCNG)			< 0.001		27.1

CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC ...................................................................................................1................... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1......... 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
2	(ANNN)			0.244		1.43

CP000580.1/1312753-1312635 GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC GGUCAUGAGUGCCAGCGUCAAGCCCCGGCUUGCUGGCCGGCAACCCUCCAACCGCGGUGGGGUGCCCCGGGUGAUGACCAGGUUGAGUAGCCGUGACGGCUACGCGGCAAGCGCGGGUC ...................................................................................................1................... .........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1......... 12345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789
	NCM			p-value	NCM frequency (per structure per nucleotide)	Means ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).