D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major
D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences
J. Mol. Biol., 435 (2023)

Small Cajal body specific RNA 1   (Rfam: RF00553)

Seed sequences
All NCMs (CSV file) (all) positive sequences (all) negative sequences (random) (training) positive sequences (training) negative sequences (testing) positive sequences (testing) negative sequences 

Options
Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN
Rfam
D-ORB
Augmented
U(RY)A
(NU)
(.ANNR.)
92.3
100.0
92.3
U(RY)A

% of positive sequence with ORB





Deep neural network:

5-fold cross-validation: 99.3 %
(± 0.168 %)
Decision tree:

5-fold cross-validation: 89.2 %
(± 5.09 %)
D-ORB structure
D-ORB structure decision tree:

5-fold cross-validation: 86.3 %
(± 7.05 %)
of AAPE02033950.1/32348-32184
AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
.(((((((((((..((((((((((((((((((((((((((((..)))))))))).))))))....)))))))))))))))))))))))(((((..)))((((((((..))))))))((((((((((((....)))))))(((((((..)))))))))))).)..)
...................................................................................................1.................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.....
123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345

abstract shape: (()())(()())

Number of sequences
Structure ORBs (out of 26) (%)
1 U(RY)A
 24 92.3
>AAGW02062815.1/2702-2537
CAGCACUUGAUACUAACCGAGCUAUCUGCAUCCUGGUCUUGUGUCAAAGGCUUGGGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUCAAAACAAAAGCCAUGAGGCUUUUAAGCCCAGAGUGUAAAGACACACUCUGAGUUAUAACUCAGAGGCACAGCU
..................................................................................................................................................(..)................
>ABDC01243130.1/621-456
UAGCACUUGAUACUAACCAAGCUAUCUAUAUCUUAGUCUCACGUCAAAGGUUCGUGAAGUAUUGUGAGAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGCCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAAAGGCACAACU
..................................................................................................................................................(..)................
>AAPE02046649.1/14668-14826
CAGCACUUGAUACUAACUGAGCUGUCUGUGUCCUAGCCUUGUGUCGCAGGCGUGCGCUGUGUGCUGAUAACUAGAUUGAACAAGUGCCGUAGUAAAGCAAAACCCUGAGUCUCUAAGCCCAGUGUGUAAGACACUGAGUUAUAAAUCGGUGGCAUACCU
...........................................................................................................................................(..)................
>AALT01582549.1/358-522
UAGCACUUGAUACUAGCCGAGCUAUCUGUGUCCUAGCCUUGAUGAAAGGCUUGUGAUACGAUGUGAUAGCUGGGUUUAAAAAGUGCAAUAUUAAAACAAAAGCCAUGAGUCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCACAGGUACAGCU
...................................................................................(..)..............................................................................
>AAWZ02032466.1/16322-16487
AAGCACUUGAUACUAACCAAGCCAUCUCUACUUUUGUUCUCUUAUAUAGAGUGCAGAAGUACAACUAGUGAUUGGCUGGGUCUAAAAAGUGCAACAUGAAAGUAAGCCAUGUGAUUAAGCUCAAUGUGUGCAGGAUCACACUGGGUUAUAACACAGCGGCACAUAC
..................................................................................................................................................(..)................
>ABDC01248697.1/770-617
GAGCUCUCUGGUGUCUUUUCUUAUAAGGACACUGAUUCUAUCAGAUGAGGGUCCCUAGCUGGGUUUAAGAAGUGCAAUAUUUAAACAAAAGCCAUGAACUUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAAUUCAGAGGCAUAAUU
........................................................................(..)..............................................................................
>AL671190.10/55894-55730
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUCGUCUUGUUUAAAGGCUUGUGAUAUGCUGUGGUAGUUGGGUUGCAGAAGUGCGAUAUUAAAGUAAAAGCCAUGAGUCUUUUAGGCCCAGUGUGUAAAGACACAUUCUGAGUUAUAACUCAGAGGCACAUUU
.................................................................................................................................................(..)................
>AAQR03036882.1/538-700
CAGCAUUUGAUACUAACUGAGCUAUCUAUAUCUUAUCUUUGUGCCAAAGGCUUAUGAUGUGUUGUGAUAGCUGGUGUACGAAGUACAGUAUUAAAAUAAAGUUAUAAGUCUCUUAAUCCUGGUUGUAAAGAUACACCCUGAGUUAUAACUCAAAGUUACAACU
...............................................................................................................................................(..)................
>AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
.................................................................................................................................................(..)................
>AL020997.1/124636-124801
CAGCACUUGAUACUAACCGAGCUGUCUAUAUCCUAGCCUUGUGUCAAAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGUCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAACU
....................................................................................(..)..............................................................................
>AAGV020447408.1/1046-883
CAACAUUUGAUAAUAACUGAGCUAUCUUUAGCUUAGCUUUAUGUCCAAGACUCGUGAUGUGUUGUGAUAGCUGGGUGUAAGAACUGCUCUAUCAACAGAAGUCAUGAGCCCUUUAUGCCCAGUAUGUAAAGACACACUCUGAGUUAUAACUCAAAGUCACAACA
................................................................................................................................................(..)................
>ABDC01122790.1/1637-1789
AAUUACAAUACUACCAAACAAUGAAAUAUUAGGUAGCCAUUUAAAAGUCACAUUUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGACUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAGUU
.....................................................................................................................................(..)................
>ABDC01297581.1/979-831
AAGCUAGAGGCUAGACACCUUCGGUGGUGGGUAUAGGUUUUUGUCCCUGGUUGCUGGGUUUGUGUUGUGCGAUAUUAAAACAAAAGCCAUGAGACUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAGUU
.................................................................................................................................(..)................
>AAYZ01435462.1/3762-3929
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUGGUCUUGUGACAAAGGCUUGUGAUAAGUGUUGUGAUAGCUGGGUUUAAAAAGUGCAAUAUUAAAACAGAAGCCAUGAGUCUUUUAAGCCCAGAGUGUAAAGUCACACUCUGAGUUAUAACUCAGAGGCACAACU
....................................................................................................................................................(..)................
>AAVX01044606.1/1599-1436
AUGCACCAGAUACUAACCUGGCUAUCUAUGUCAAAGCUCUGUUGUAGAUCUGAGACAAUCCUGUGAUUGUUGGGUCCAAAUGGUGCAAGAUUAAACCAAGCCAUGAGUACAUAUUAGCUCAUCGUGCGCAGAAACACUAUGGGUUAUAACUUAGAGGCACAAUG
................................................................................................................................................(..)................
>AAPY01115810.1/1223-1386
UGGCACUUGAUACUCACCGAGCUGUCUAAAUCCUGGUCUUGUCAGAGGCUUGUGAUACGCCGUGACAGCUGGGUUAAAGAAGUGCAAUAUAAACACGAAAGCCCUGAGUCUUCGAAGCCCAGUGUGUGGAGACACGCUCUGAGUUAUAGCUCAGAGGCACAGCU
................................................................................................................................................(..)................
>AAKN02028641.1/76742-76577
CAGCACUUGAUACUAACCGAGCUAUCUAUAUCCUGGCUUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAGCAAAAGCCAUGAGAUCAUUAAGCCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGGCACAACU
..................................................................................................................................................(..)................
>AAKN02026384.1/16353-16190
CAGCACUUGAUACUAACCGAGCUGUCUAUAUCCUGGCCUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAUCAUUAAGUCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGACACAACU
................................................................................................................................................(..)................
>AAIY01206707.1/10765-10603
CAGCACUUGAUACUAACCGAGCUAUCUAUGUCCUAGCCUAUGUCAAAGGCUUGUGAUGUGUUGUGAUCGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAGCCAUGAGUCUUUUAAGCCCAGGGUGUAAAGCCACACUCUGAGUUAUAACUCAAAGGCACAACU
...................................................................................(..)............................................................................
>AAKN02046889.1/258733-258563
AUGUCCUUAAAGGUCCACGUGUUAAGCUAUCUAUAUCCUGGCCUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAGCAAAAGCCAUGAGAUCAUUAAGCCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGGCACAACU
.......................................................................................................................................................(..)................
>AALT01399912.1/1832-1997
UAGCCCUUAAUGCUAGCUGAGCUCUCUGUAUUCCAGCCUUGAUGACAGGCUUGUGGUAGCGUGUGAGAGCUGAGUUCAAGAAGCGUGAUAUUAAAACAAAAGCCAUGACUUUUUGAAACCAGGCUUGCCAAGACACGCUGUGAGUUCACAACUCAUCUGCACAAAU
..........................(..)........................................................................................................................................
>AAPE02024871.1/982-1146
CAGCACUCGAUACUAACCCAGCUAUCUGCAUCCUAGCCUUGUGCCAAAGGCUUGUGAUGUGCUGUGAUAACUGGGUUGAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUUUAAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
.................................................................................................................................................(..)................
>AADN03008214.1/139309-139474
GAGCACUUGAUACUAACCGAGCUAUCUGUAUCCCAGGUCUCCUCCAGAGGUCUGAGGUAUACUUUGUGAUUGCUGGGUCUGAAAAGUGCAACAUUAAAACAAGCCCUGCAGUGUUUAAGCUCAGUGUGUAAAGGAUGACACUGGGUUAUAGCUCAGAGGCACAGAA
..................................................................................................................................................(..)................
>AAFR03060621.1/25521-25687
AAGCACUUGAUACUAACCAAGCUAUCUGUAUCCUGAUGCCGCUCCAGAAGUUGGGAUGUAUCUUGUGAUAGCUGGGUUUUAUAAGUGCAAUAUUAAAGUAAACCAUGAGUCUUUUAAGCCCAGCAUGUGGAGUUGAGCAUGCUGGGUUAUAACUCAAAGGUACAGCA
.....................................................................................(..)..............................................................................
2 U(RY)A
(NU)
 21 80.8
>AAKN02026384.1/16353-16190
CAGCACUUGAUACUAACCGAGCUGUCUAUAUCCUGGCCUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAUCAUUAAGUCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGACACAACU
.........................................(..)...................................................................................................(..)................
>AAPY01115810.1/1223-1386
UGGCACUUGAUACUCACCGAGCUGUCUAAAUCCUGGUCUUGUCAGAGGCUUGUGAUACGCCGUGACAGCUGGGUUAAAGAAGUGCAAUAUAAACACGAAAGCCCUGAGUCUUCGAAGCCCAGUGUGUGGAGACACGCUCUGAGUUAUAGCUCAGAGGCACAGCU
.....................................(..).......................................................................................................(..)................
>AAIY01206707.1/10765-10603
CAGCACUUGAUACUAACCGAGCUAUCUAUGUCCUAGCCUAUGUCAAAGGCUUGUGAUGUGUUGUGAUCGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAGCCAUGAGUCUUUUAAGCCCAGGGUGUAAAGCCACACUCUGAGUUAUAACUCAAAGGCACAACU
...........(..)....................................................................(..)............................................................................
>AAPE02024871.1/982-1146
CAGCACUCGAUACUAACCCAGCUAUCUGCAUCCUAGCCUUGUGCCAAAGGCUUGUGAUGUGCUGUGAUAACUGGGUUGAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUUUAAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
........(..).....................................................................................................................................(..)................
>AAKN02046889.1/258733-258563
AUGUCCUUAAAGGUCCACGUGUUAAGCUAUCUAUAUCCUGGCCUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAGCAAAAGCCAUGAGAUCAUUAAGCCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGGCACAACU
..............................................(..).....................................................................................................(..)................
>AAKN02028641.1/76742-76577
CAGCACUUGAUACUAACCGAGCUAUCUAUAUCCUGGCUUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAGCAAAAGCCAUGAGAUCAUUAAGCCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGGCACAACU
.........................................(..).....................................................................................................(..)................
>AADN03008214.1/139309-139474
GAGCACUUGAUACUAACCGAGCUAUCUGUAUCCCAGGUCUCCUCCAGAGGUCUGAGGUAUACUUUGUGAUUGCUGGGUCUGAAAAGUGCAACAUUAAAACAAGCCCUGCAGUGUUUAAGCUCAGUGUGUAAAGGAUGACACUGGGUUAUAGCUCAGAGGCACAGAA
..............................................................(..)................................................................................(..)................
>AALT01582549.1/358-522
UAGCACUUGAUACUAGCCGAGCUAUCUGUGUCCUAGCCUUGAUGAAAGGCUUGUGAUACGAUGUGAUAGCUGGGUUUAAAAAGUGCAAUAUUAAAACAAAAGCCAUGAGUCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCACAGGUACAGCU
...........(..)....................................................................(..)..............................................................................
>AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
.........................................(..)....................................................................................................(..)................
>AAWZ02032466.1/16322-16487
AAGCACUUGAUACUAACCAAGCCAUCUCUACUUUUGUUCUCUUAUAUAGAGUGCAGAAGUACAACUAGUGAUUGGCUGGGUCUAAAAAGUGCAACAUGAAAGUAAGCCAUGUGAUUAAGCUCAAUGUGUGCAGGAUCACACUGGGUUAUAACACAGCGGCACAUAC
..........................................(..)....................................................................................................(..)................
>AL671190.10/55894-55730
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUCGUCUUGUUUAAAGGCUUGUGAUAUGCUGUGGUAGUUGGGUUGCAGAAGUGCGAUAUUAAAGUAAAAGCCAUGAGUCUUUUAGGCCCAGUGUGUAAAGACACAUUCUGAGUUAUAACUCAGAGGCACAUUU
.........................................(..)....................................................................................................(..)................
>AL020997.1/124636-124801
CAGCACUUGAUACUAACCGAGCUGUCUAUAUCCUAGCCUUGUGUCAAAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGUCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAACU
.........................................(..).......................................(..)..............................................................................
>ABDC01243130.1/621-456
UAGCACUUGAUACUAACCAAGCUAUCUAUAUCUUAGUCUCACGUCAAAGGUUCGUGAAGUAUUGUGAGAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGCCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAAAGGCACAACU
....................................................(..)..........................................................................................(..)................
>AAVX01044606.1/1599-1436
AUGCACCAGAUACUAACCUGGCUAUCUAUGUCAAAGCUCUGUUGUAGAUCUGAGACAAUCCUGUGAUUGUUGGGUCCAAAUGGUGCAAGAUUAAACCAAGCCAUGAGUACAUAUUAGCUCAUCGUGCGCAGAAACACUAUGGGUUAUAACUUAGAGGCACAAUG
........................................(..)....................................................................................................(..)................
>ABDC01297581.1/979-831
AAGCUAGAGGCUAGACACCUUCGGUGGUGGGUAUAGGUUUUUGUCCCUGGUUGCUGGGUUUGUGUUGUGCGAUAUUAAAACAAAAGCCAUGAGACUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAGUU
.........................(..)....................................................................................................(..)................
>AAFR03060621.1/25521-25687
AAGCACUUGAUACUAACCAAGCUAUCUGUAUCCUGAUGCCGCUCCAGAAGUUGGGAUGUAUCUUGUGAUAGCUGGGUUUUAUAAGUGCAAUAUUAAAGUAAACCAUGAGUCUUUUAAGCCCAGCAUGUGGAGUUGAGCAUGCUGGGUUAUAACUCAAAGGUACAGCA
........................(..).........................................................(..)..............................................................................
>AAQR03036882.1/538-700
CAGCAUUUGAUACUAACUGAGCUAUCUAUAUCUUAUCUUUGUGCCAAAGGCUUAUGAUGUGUUGUGAUAGCUGGUGUACGAAGUACAGUAUUAAAAUAAAGUUAUAAGUCUCUUAAUCCUGGUUGUAAAGAUACACCCUGAGUUAUAACUCAAAGUUACAACU
........................(..)...................................................................................................................(..)................
>AAYZ01435462.1/3762-3929
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUGGUCUUGUGACAAAGGCUUGUGAUAAGUGUUGUGAUAGCUGGGUUUAAAAAGUGCAAUAUUAAAACAGAAGCCAUGAGUCUUUUAAGCCCAGAGUGUAAAGUCACACUCUGAGUUAUAACUCAGAGGCACAACU
.....................................(..)...........................................................................................................(..)................
>AAGV020447408.1/1046-883
CAACAUUUGAUAAUAACUGAGCUAUCUUUAGCUUAGCUUUAUGUCCAAGACUCGUGAUGUGUUGUGAUAGCUGGGUGUAAGAACUGCUCUAUCAACAGAAGUCAUGAGCCCUUUAUGCCCAGUAUGUAAAGACACACUCUGAGUUAUAACUCAAAGUCACAACA
........................(..)....................................................................................................................(..)................
>AAGW02062815.1/2702-2537
CAGCACUUGAUACUAACCGAGCUAUCUGCAUCCUGGUCUUGUGUCAAAGGCUUGGGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUCAAAACAAAAGCCAUGAGGCUUUUAAGCCCAGAGUGUAAAGACACACUCUGAGUUAUAACUCAGAGGCACAGCU
...............................(..)...............................................................................................................(..)................
>AAPE02046649.1/14668-14826
CAGCACUUGAUACUAACUGAGCUGUCUGUGUCCUAGCCUUGUGUCGCAGGCGUGCGCUGUGUGCUGAUAACUAGAUUGAACAAGUGCCGUAGUAAAGCAAAACCCUGAGUCUCUAAGCCCAGUGUGUAAGACACUGAGUUAUAAAUCGGUGGCAUACCU
.......................................(..)................................................................................................(..)................
3 U(RY)A
(NU)
(.ANNR.)
 15 57.7
>AAWZ02032466.1/16322-16487
AAGCACUUGAUACUAACCAAGCCAUCUCUACUUUUGUUCUCUUAUAUAGAGUGCAGAAGUACAACUAGUGAUUGGCUGGGUCUAAAAAGUGCAACAUGAAAGUAAGCCAUGUGAUUAAGCUCAAUGUGUGCAGGAUCACACUGGGUUAUAACACAGCGGCACAUAC
..........................................(..)...........................................................................(.....)..................(..)................
>AAGV020447408.1/1046-883
CAACAUUUGAUAAUAACUGAGCUAUCUUUAGCUUAGCUUUAUGUCCAAGACUCGUGAUGUGUUGUGAUAGCUGGGUGUAAGAACUGCUCUAUCAACAGAAGUCAUGAGCCCUUUAUGCCCAGUAUGUAAAGACACACUCUGAGUUAUAACUCAAAGUCACAACA
........................(..)..................................................................................................(....)............(..)................
>AAQR03036882.1/538-700
CAGCAUUUGAUACUAACUGAGCUAUCUAUAUCUUAUCUUUGUGCCAAAGGCUUAUGAUGUGUUGUGAUAGCUGGUGUACGAAGUACAGUAUUAAAAUAAAGUUAUAAGUCUCUUAAUCCUGGUUGUAAAGAUACACCCUGAGUUAUAACUCAAAGUUACAACU
........................(..)................................................(.....)............................................................(..)................
>AL020997.1/124636-124801
CAGCACUUGAUACUAACCGAGCUGUCUAUAUCCUAGCCUUGUGUCAAAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGUCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAACU
.........................................(..)....................................................................................(....)...........(..)................
>AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
.........................................(..)..................................................................................(....)............(..)................
>AL671190.10/55894-55730
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUCGUCUUGUUUAAAGGCUUGUGAUAUGCUGUGGUAGUUGGGUUGCAGAAGUGCGAUAUUAAAGUAAAAGCCAUGAGUCUUUUAGGCCCAGUGUGUAAAGACACAUUCUGAGUUAUAACUCAGAGGCACAUUU
.........................................(..)..................................................................................(....)............(..)................
>ABDC01243130.1/621-456
UAGCACUUGAUACUAACCAAGCUAUCUAUAUCUUAGUCUCACGUCAAAGGUUCGUGAAGUAUUGUGAGAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGCCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAAAGGCACAACU
....................................................(..).........................................................................(....)...........(..)................
>ABDC01297581.1/979-831
AAGCUAGAGGCUAGACACCUUCGGUGGUGGGUAUAGGUUUUUGUCCCUGGUUGCUGGGUUUGUGUUGUGCGAUAUUAAAACAAAAGCCAUGAGACUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAGUU
.........................(..)..................................................................................(....)............(..)................
>AAPE02024871.1/982-1146
CAGCACUCGAUACUAACCCAGCUAUCUGCAUCCUAGCCUUGUGCCAAAGGCUUGUGAUGUGCUGUGAUAACUGGGUUGAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUUUAAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
........(..)................................................................................(.....)..............................................(..)................
>AAKN02046889.1/258733-258563
AUGUCCUUAAAGGUCCACGUGUUAAGCUAUCUAUAUCCUGGCCUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAGCAAAAGCCAUGAGAUCAUUAAGCCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGGCACAACU
..............................................(..)...................................................................................(....)............(..)................
>AAVX01044606.1/1599-1436
AUGCACCAGAUACUAACCUGGCUAUCUAUGUCAAAGCUCUGUUGUAGAUCUGAGACAAUCCUGUGAUUGUUGGGUCCAAAUGGUGCAAGAUUAAACCAAGCCAUGAGUACAUAUUAGCUCAUCGUGCGCAGAAACACUAUGGGUUAUAACUUAGAGGCACAAUG
........................................(..)...................................................................................(.....)..........(..)................
>AADN03008214.1/139309-139474
GAGCACUUGAUACUAACCGAGCUAUCUGUAUCCCAGGUCUCCUCCAGAGGUCUGAGGUAUACUUUGUGAUUGCUGGGUCUGAAAAGUGCAACAUUAAAACAAGCCCUGCAGUGUUUAAGCUCAGUGUGUAAAGGAUGACACUGGGUUAUAGCUCAGAGGCACAGAA
..............................................................(..)................................................................(....)..........(..)................
>AAGW02062815.1/2702-2537
CAGCACUUGAUACUAACCGAGCUAUCUGCAUCCUGGUCUUGUGUCAAAGGCUUGGGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUCAAAACAAAAGCCAUGAGGCUUUUAAGCCCAGAGUGUAAAGACACACUCUGAGUUAUAACUCAGAGGCACAGCU
...............................(..).............................................................................................(....)............(..)................
>AAYZ01435462.1/3762-3929
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUGGUCUUGUGACAAAGGCUUGUGAUAAGUGUUGUGAUAGCUGGGUUUAAAAAGUGCAAUAUUAAAACAGAAGCCAUGAGUCUUUUAAGCCCAGAGUGUAAAGUCACACUCUGAGUUAUAACUCAGAGGCACAACU
.....................................(..).........................................................................................(......)..........(..)................
>AAPY01115810.1/1223-1386
UGGCACUUGAUACUCACCGAGCUGUCUAAAUCCUGGUCUUGUCAGAGGCUUGUGAUACGCCGUGACAGCUGGGUUAAAGAAGUGCAAUAUAAACACGAAAGCCCUGAGUCUUCGAAGCCCAGUGUGUGGAGACACGCUCUGAGUUAUAGCUCAGAGGCACAGCU
.....................................(..)....................................................(....).............................................(..)................

>AAGW02062815.1/2702-2537
CAGCACUUGAUACUAACCGAGCUAUCUGCAUCCUGGUCUUGUGUCAAAGGCUUGGGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUCAAAACAAAAGCCAUGAGGCUUUUAAGCCCAGAGUGUAAAGACACACUCUGAGUUAUAACUCAGAGGCACAGCU
..................................................................................................................................................(..)................
...............................(..)...............................................................................................................(..)................
...............................(..).............................................................................................(....)............(..)................
>ABDC01243130.1/621-456
UAGCACUUGAUACUAACCAAGCUAUCUAUAUCUUAGUCUCACGUCAAAGGUUCGUGAAGUAUUGUGAGAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGCCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAAAGGCACAACU
..................................................................................................................................................(..)................
....................................................(..)..........................................................................................(..)................
....................................................(..).........................................................................(....)...........(..)................
>AAWZ02032466.1/16322-16487
AAGCACUUGAUACUAACCAAGCCAUCUCUACUUUUGUUCUCUUAUAUAGAGUGCAGAAGUACAACUAGUGAUUGGCUGGGUCUAAAAAGUGCAACAUGAAAGUAAGCCAUGUGAUUAAGCUCAAUGUGUGCAGGAUCACACUGGGUUAUAACACAGCGGCACAUAC
..................................................................................................................................................(..)................
..........................................(..)....................................................................................................(..)................
..........................................(..)...........................................................................(.....)..................(..)................
>AL671190.10/55894-55730
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUCGUCUUGUUUAAAGGCUUGUGAUAUGCUGUGGUAGUUGGGUUGCAGAAGUGCGAUAUUAAAGUAAAAGCCAUGAGUCUUUUAGGCCCAGUGUGUAAAGACACAUUCUGAGUUAUAACUCAGAGGCACAUUU
.................................................................................................................................................(..)................
.........................................(..)....................................................................................................(..)................
.........................................(..)..................................................................................(....)............(..)................
>AAQR03036882.1/538-700
CAGCAUUUGAUACUAACUGAGCUAUCUAUAUCUUAUCUUUGUGCCAAAGGCUUAUGAUGUGUUGUGAUAGCUGGUGUACGAAGUACAGUAUUAAAAUAAAGUUAUAAGUCUCUUAAUCCUGGUUGUAAAGAUACACCCUGAGUUAUAACUCAAAGUUACAACU
...............................................................................................................................................(..)................
........................(..)...................................................................................................................(..)................
........................(..)................................................(.....)............................................................(..)................
>AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
.................................................................................................................................................(..)................
.........................................(..)....................................................................................................(..)................
.........................................(..)..................................................................................(....)............(..)................
>AL020997.1/124636-124801
CAGCACUUGAUACUAACCGAGCUGUCUAUAUCCUAGCCUUGUGUCAAAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGUCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAACU
....................................................................................(..)..............................................................................
.........................................(..).......................................(..)..............................................................................
.........................................(..)....................................................................................(....)...........(..)................
>AAGV020447408.1/1046-883
CAACAUUUGAUAAUAACUGAGCUAUCUUUAGCUUAGCUUUAUGUCCAAGACUCGUGAUGUGUUGUGAUAGCUGGGUGUAAGAACUGCUCUAUCAACAGAAGUCAUGAGCCCUUUAUGCCCAGUAUGUAAAGACACACUCUGAGUUAUAACUCAAAGUCACAACA
................................................................................................................................................(..)................
........................(..)....................................................................................................................(..)................
........................(..)..................................................................................................(....)............(..)................
>ABDC01297581.1/979-831
AAGCUAGAGGCUAGACACCUUCGGUGGUGGGUAUAGGUUUUUGUCCCUGGUUGCUGGGUUUGUGUUGUGCGAUAUUAAAACAAAAGCCAUGAGACUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAGUU
.................................................................................................................................(..)................
.........................(..)....................................................................................................(..)................
.........................(..)..................................................................................(....)............(..)................
>AAYZ01435462.1/3762-3929
CAGCACUUGAUACUAACCGAGCUAUCUGUAUCCUGGUCUUGUGACAAAGGCUUGUGAUAAGUGUUGUGAUAGCUGGGUUUAAAAAGUGCAAUAUUAAAACAGAAGCCAUGAGUCUUUUAAGCCCAGAGUGUAAAGUCACACUCUGAGUUAUAACUCAGAGGCACAACU
....................................................................................................................................................(..)................
.....................................(..)...........................................................................................................(..)................
.....................................(..).........................................................................................(......)..........(..)................
>AAVX01044606.1/1599-1436
AUGCACCAGAUACUAACCUGGCUAUCUAUGUCAAAGCUCUGUUGUAGAUCUGAGACAAUCCUGUGAUUGUUGGGUCCAAAUGGUGCAAGAUUAAACCAAGCCAUGAGUACAUAUUAGCUCAUCGUGCGCAGAAACACUAUGGGUUAUAACUUAGAGGCACAAUG
................................................................................................................................................(..)................
........................................(..)....................................................................................................(..)................
........................................(..)...................................................................................(.....)..........(..)................
>AAPY01115810.1/1223-1386
UGGCACUUGAUACUCACCGAGCUGUCUAAAUCCUGGUCUUGUCAGAGGCUUGUGAUACGCCGUGACAGCUGGGUUAAAGAAGUGCAAUAUAAACACGAAAGCCCUGAGUCUUCGAAGCCCAGUGUGUGGAGACACGCUCUGAGUUAUAGCUCAGAGGCACAGCU
................................................................................................................................................(..)................
.....................................(..).......................................................................................................(..)................
.....................................(..)....................................................(....).............................................(..)................
>AAKN02046889.1/258733-258563
AUGUCCUUAAAGGUCCACGUGUUAAGCUAUCUAUAUCCUGGCCUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAGCAAAAGCCAUGAGAUCAUUAAGCCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGGCACAACU
.......................................................................................................................................................(..)................
..............................................(..).....................................................................................................(..)................
..............................................(..)...................................................................................(....)............(..)................
>AAPE02024871.1/982-1146
CAGCACUCGAUACUAACCCAGCUAUCUGCAUCCUAGCCUUGUGCCAAAGGCUUGUGAUGUGCUGUGAUAACUGGGUUGAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUUUAAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
.................................................................................................................................................(..)................
........(..).....................................................................................................................................(..)................
........(..)................................................................................(.....)..............................................(..)................
>AADN03008214.1/139309-139474
GAGCACUUGAUACUAACCGAGCUAUCUGUAUCCCAGGUCUCCUCCAGAGGUCUGAGGUAUACUUUGUGAUUGCUGGGUCUGAAAAGUGCAACAUUAAAACAAGCCCUGCAGUGUUUAAGCUCAGUGUGUAAAGGAUGACACUGGGUUAUAGCUCAGAGGCACAGAA
..................................................................................................................................................(..)................
..............................................................(..)................................................................................(..)................
..............................................................(..)................................................................(....)..........(..)................
>AAPE02046649.1/14668-14826
CAGCACUUGAUACUAACUGAGCUGUCUGUGUCCUAGCCUUGUGUCGCAGGCGUGCGCUGUGUGCUGAUAACUAGAUUGAACAAGUGCCGUAGUAAAGCAAAACCCUGAGUCUCUAAGCCCAGUGUGUAAGACACUGAGUUAUAAAUCGGUGGCAUACCU
...........................................................................................................................................(..)................
.......................................(..)................................................................................................(..)................
>AALT01582549.1/358-522
UAGCACUUGAUACUAGCCGAGCUAUCUGUGUCCUAGCCUUGAUGAAAGGCUUGUGAUACGAUGUGAUAGCUGGGUUUAAAAAGUGCAAUAUUAAAACAAAAGCCAUGAGUCUUUUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCACAGGUACAGCU
...................................................................................(..)..............................................................................
...........(..)....................................................................(..)..............................................................................
>AAKN02028641.1/76742-76577
CAGCACUUGAUACUAACCGAGCUAUCUAUAUCCUGGCUUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAGCAAAAGCCAUGAGAUCAUUAAGCCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGGCACAACU
..................................................................................................................................................(..)................
.........................................(..).....................................................................................................(..)................
>AAKN02026384.1/16353-16190
CAGCACUUGAUACUAACCGAGCUGUCUAUAUCCUGGCCUUAUAUCUAAAGCUUGUGAUAUGUUGUGAUAGUUGGGUUGAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAUCAUUAAGUCCAUUGUGUAAAGAUGCACUCUGAGUUAUAACUCAAAGACACAACU
................................................................................................................................................(..)................
.........................................(..)...................................................................................................(..)................
>AAIY01206707.1/10765-10603
CAGCACUUGAUACUAACCGAGCUAUCUAUGUCCUAGCCUAUGUCAAAGGCUUGUGAUGUGUUGUGAUCGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAGCCAUGAGUCUUUUAAGCCCAGGGUGUAAAGCCACACUCUGAGUUAUAACUCAAAGGCACAACU
...................................................................................(..)............................................................................
...........(..)....................................................................(..)............................................................................
>AAFR03060621.1/25521-25687
AAGCACUUGAUACUAACCAAGCUAUCUGUAUCCUGAUGCCGCUCCAGAAGUUGGGAUGUAUCUUGUGAUAGCUGGGUUUUAUAAGUGCAAUAUUAAAGUAAACCAUGAGUCUUUUAAGCCCAGCAUGUGGAGUUGAGCAUGCUGGGUUAUAACUCAAAGGUACAGCA
.....................................................................................(..)..............................................................................
........................(..).........................................................(..)..............................................................................
>ABDC01248697.1/770-617
GAGCUCUCUGGUGUCUUUUCUUAUAAGGACACUGAUUCUAUCAGAUGAGGGUCCCUAGCUGGGUUUAAGAAGUGCAAUAUUUAAACAAAAGCCAUGAACUUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAAUUCAGAGGCAUAAUU
........................................................................(..)..............................................................................
>ABDC01122790.1/1637-1789
AAUUACAAUACUACCAAACAAUGAAAUAUUAGGUAGCCAUUUAAAAGUCACAUUUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCAUGAGACUUGUAAGCCCAGUGUGUAAAGAUACACUCUGAGUUAUAACUCAGAGGCACAGUU
.....................................................................................................................................(..)................
>AALT01399912.1/1832-1997
UAGCCCUUAAUGCUAGCUGAGCUCUCUGUAUUCCAGCCUUGAUGACAGGCUUGUGGUAGCGUGUGAGAGCUGAGUUCAAGAAGCGUGAUAUUAAAACAAAAGCCAUGACUUUUUGAAACCAGGCUUGCCAAGACACGCUGUGAGUUCACAACUCAUCUGCACAAAU
..........................(..)........................................................................................................................................

ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio
1 U(RY)A < 0.001 12.8
AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
...................................................................................................1.................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.....
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2 (NU) < 0.001 2.43
AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
...................................................................................................1.................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.....
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3 (.ANNR.) 0.00691 1.11
AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
...................................................................................................1.................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.....
123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio

NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio
1 U(AU)A < 0.001 29.4
AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
...................................................................................................1.................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.....
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2 .N. (URB) < 0.001 0.699
3 R(U(A)()) 0.21 7.29
AAPE02033950.1/32348-32184
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
CAGCACUUGAUACUAACCGAGCUAUCUACAUCCUAGCCUUGUGUCAGAGGCUUGUGAUGUGUUGUGAUAGCUGGGUUUAAGAAGUGCAAUAUUAAAACAAAAGCCGUGAGUCUGUUAGCCCAGUGUGUAAAGACACACUCUGAGUUAUAACUCAGUGGCACAACU
...................................................................................................1.................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.....
123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345678901234567890123456789012345
NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).