D-ORB

The Overrepresented RNA Blocks

M.J. Dupont, F. Major
D-ORB: A Web Server to Extract Structural Features of Related But Unaligned RNA Sequences
J. Mol. Biol., 435 (2023)

yybP-ykoY manganese riboswitch   (Rfam: RF00080)

Seed sequences
All NCMs (CSV file) (all) positive sequences (all) negative sequences (random) (training) positive sequences (training) negative sequences (testing) positive sequences (testing) negative sequences 

Options
Negatives sequences: Random sequences of similar lengths
ORBs positions sequence: Best consensus structure-matching sequence
Motifs: 162,498 motifs on the alphabet ACGURYN
Rfam
D-ORB
Augmented
(.CAY.)
(.NG.)
(().N.)
94.7
100.0
100.0

% of positive sequence with ORB





Deep neural network:

5-fold cross-validation: 99.5 %
(± 0.106 %)
Decision tree:

5-fold cross-validation: 86.7 %
(± 7.69 %)
D-ORB structure
D-ORB structure decision tree:

5-fold cross-validation: 71.2 %
(± 7.98 %)
of AM406670.1/393403-393588
AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
(((((((((((((((.....)))))))))))))))(((((((((..)))))))))(((((((((((((...))(((((..))))))))))))))))(((((((((((..((((((((((((((.(((((.((((((((.....))..))))))))))).)))))))))))))))))))))))))..
...................................................................................................1......................................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.........7.........8......
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abstract shape: (()(()(()()))())

Number of sequences
Structure ORBs (out of 19) (%)
1 (.CAY.)
 18 94.7
>AF270169.1/2621-2476
AAAACUGUCAGAGGGGAGUAACUUGAGAAUAGUUAUUGAAUGCAUUUAAACCGAUAAUAACUAUUCAACACUUUGUCGUCAUUACGAAGAUAAGUCUUCCGGUAAAGUGGGCAAAAAUAUUGCUAAGUGAGACCUUUGCUAUUAAA
..............................................................................(....)..............................................................
>Y14370.1/1315-1188
CAUUUUGUCAGAGGGGAGUAACUUAAGAAUCAUGACCGUAUAAAUGAUUCGACACUUUAUCGUCAUUACGAAGAUAUCUUCCGGUAAAGUGGGCAAUUAAAUUGCUUAGUGAGACCUUUGCUAUUUAU
..............................................................(....)............................................................
>CU207211.1/3280200-3280389
CUGCUAUCAUUCGCCCCGAACAUUGGGGAGUAGCCGGCCUUAGUCAACUAAGGGAUCUGCGUCAACAUUCUUGGCCCGCAGGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUCGCUCAAAUGACGACCGCAUGGGCCGGGGUCGCUGUUUGCGCUUUGGUUAUUAUUCCGGCCCCAGAAAGUU
.................(.....)......................................................................................................................................................................
>CR555306.1/995584-995774
CCGGUAGAAUUCGCGCCGUCAUCAGGGAGUAGCCGCCUGCGAGCCUUCGCAGGGACCACGUCAACAGACUUGCGCGUCGCGCAUGGCGUGGCCAGCCUUCGGGCCUGGCGAGACUUUUGGCUGCAUGCCCUCCGAUUUUUCGGGCCCGGGAGGCGUGCGGUCAUCGGUCAUCAGCCGGCCCGGAGAACCUG
.................(....)........................................................................................................................................................................
>AL954747.1/2722783-2722598
CUGUUACAAUUUGCCGGUCAUUGGGGAGUAGCCGCUCUUCGUUUCGAAGGGGCUUACGUCAACAUACUUGACCGGCAGGUCAUGGCGUAAGCGGUUCUAAGCCUGGCAAGACCUUUGACCACAAUGCCUCCGAUUUGGCCGGGGAGGCGUUGUGGUCAAUCGUCUGUAAACCGGCCGGAGAACAUU
.............................................................(...)........................................................................................................................
>CP000103.1/662385-662565
CAAGUAGAAUAUUCCGGUCAUCGGGGAGUAGCUUCCUUCCGUCGAAUAGAAGGGCUUGCAUCAACAUACUUGACCCGUGGUCGUGGUGCAAGGAGUUCGUGCCUGGCAAGACCUUUGACCACAUUGUCUCCGGAAGGGCGGGGAGAAGCCUGGUCUCGCUUCUUGUCCGGCCUGGAGCGUA
................(....)...............................................................................................................................................................
>CP000155.1/3815875-3815690
UUGCAUUAGUAUGCCCGGCGUCACUGGGGAGUAGCCUCUCUUCGCCCUGAAGAGGUUUGCGUCAACAUACUUGGCCCACAGGCCAUGGCGUAAACGGUUCCAUAACUUGGCAAGACCUUUGACUAUGCCGCACCGGUUGGGCCGGGGCGUGGCGUAGUCAUAUGGUUAAUCCGGCCCAGGAGAUUU
...........................................................................(....).........................................................................................................
>CP001052.1/4299894-4299707
CCGUUAAAAUCCCCCGGUCACUGGGGAGUAGCCUUCCUUCAUCCAUUGAAGGAGAGCGCGUCAACAUACUUGGCCUGCGGGUCAUGGCGCGUUCGACCGGGUCGGUUUGGCGAGACCAUUGACGCACUGCCUCGUUCUGGUCGGACGGGCGGCGGUGCGUCAUUGGUUUGUUAUCGACGUCCGACCGC
........................................(.....).............................................................................................................................................
>CP000555.1/403908-404093
AAUCGCGGCUCCCACCCGUCAUCGGGGAGUAGCCGCCCUGCAUCCGUUGCAGGGGCUCGCGUCAACACACUUGGCCUGCAGGCCAUGGUGCGAGCAGCUUCCACAGCCUGGCAAGACCUUUGACCGCACAGCCUCCGCGUGGCCGGAGAGGCCGUGUGGUCAUUGCGUCAUCCGGCCCAGGACCUC
.................(....)...................................................................................................................................................................
>ADGO01015088.1/632-820
CGUGUAUGCUCCCGCCCCGUCAUUGGGGAGUAACCUCCUGCGGCGUUACGCCGCCGGGCUUACAUCAACACACUUGGCCGGUUGGGCCAUGGUGUAAGCGGCUUCAGUGCUUGGUGAGACCUUUGAUCAUGUCGUUCCGGUAUGGGCCGCGGACGGCGUGGUCAAUUGUGUCCUCCGGCCCUGAACGCU
.....................................................................(...)...................................................................................................................
>FP929140.1/858523-858335
CUGAUAUACUUCGCUGGUCAUUGGGGAGUAGCCGAUCUUCGCACUGAAGAUGCUUACGUCAACACACUUGGCCCACAGGCCAUGGCGUAAGCGGUUCACACGCUUGGCAAGACCUUUGACCACAACGCCUCCGUAUUAAGGCUGGGGAUGCGUCGUGGUCAAUUGUGUCUAAUCCAGCCUGAGAAUCGU
........................................................................(....)...............................................................................................................
>AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
...................................................................(...)..................................................................................................................
>AEGR01000046.1/5080-4892
UUGUUAGAAUGCGCCCCGUCAUUGGGGAGUAGCCGCUCUUCACCGCGAAGAGGCUUGCGUCAACACACUUGGUCCAUCGGACCAUGGCGCAGGCAGCUCCUGGCCUGGCAAGACCUUUGACCACGAAGCCUCCGUUUUGGCCGGGGAUGCGUCGUGGUCAAUCGUCUCUGUACACCGGCCUUGGACAUU
.................(....)......................................................................................................................................................................
>CP000269.1/3948088-3948277
CUGCUAUCAUUACGCCUGAACAUUGGGGAGUAGCCGGCCUUUGGCAACAAAGGAAUCUGCAUCAACACUCUUGGCACGCAUGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUUGAUCAAGUGACGACCGCAUGGGCCGGGGUCGUUGUUUGGUCUUUGGUUAUUCGUCCGGCCCGAGAAAGUC
................................................................(...).........................................................................................................................
>CP001013.1/98070-98260
UCGCUAUACUCGCGGCGCUUUCGUCAUUGGGGAGUAGCCGCCCUGCGCCCGCAGGGGUUCGCGUCAACACACUUGACCCUCACGGUCAUGGCGCGAACAGCUCCAGAGCCUGGCAAGACCUUUGACCACACUGCCUCCGGAAGGGCCGGGGAUGCCGUGUGGUCUCUGGUAUUCGCUGGCCCUUGGAGAUC
.............................................................................(.....)...........................................................................................................
>CP000270.1/4748060-4747865
CCGUUAGAAUCCCCCGGUCACUGGGGAGUAGCCUUCCUUCAUCGUUUGAAGGAGAACGCGUCAACAUACUUGGCCUUGCAGGUCAUGGCGCGUUCGGCCGUGUCGGUUUGGCGAGACCAUUGACGCACUGCCUCGUUCUGGUCGGACGGGCGGCGGUGCGUCAUUGGUUUGUCGUCUACGUCCGACCGUGGAGUUG
...............................................................(...)................................................................................................................................
>ABSP01053999.1/668-852
CCGGUAGAAUCGCGCGGUCAUUGGGGAGUAGUCGCCCUCUACCCAGAGGGGCUUGCGUCAACAUACUUGACCGAUUGGUCAUGGCGCAAGCGGUUUCCUAGCUUGGCGAGACCUUUGACCAUAUCGCCUUCGGACUGGCCGGAGAAGCGGUGUGGUCAUUUGUCUUCUUCCGGCCAGGGAGCACC
............................................................(...)........................................................................................................................
>AEWG01000141.1/70250-70056
CUAGAAUCGCGCCCGCACUCGUCAUCGGGGAGUAGCCGCCCUGCCGCCCGGCAGGGGUCCGCGCCAACACGCUUGGCCCUCAGGGGCCAUGGUCCGGACAGCCCCCAGCCUGGCAAGACCGCUGACUGCGCCGCCUCCGAAUGGGCCGGGGUCGCGGCGUGGUCAAGCUCCGGUCAUGCCGGCCCGUAUCGGAUU
..............(....)...............................................................................................................................................................................
2 (.CAY.)
(.NG.)
 16 84.2
>CP000555.1/403908-404093
AAUCGCGGCUCCCACCCGUCAUCGGGGAGUAGCCGCCCUGCAUCCGUUGCAGGGGCUCGCGUCAACACACUUGGCCUGCAGGCCAUGGUGCGAGCAGCUUCCACAGCCUGGCAAGACCUUUGACCGCACAGCCUCCGCGUGGCCGGAGAGGCCGUGUGGUCAUUGCGUCAUCCGGCCCAGGACCUC
.................(....)....................................................(....).........................................................................................................
>CP000269.1/3948088-3948277
CUGCUAUCAUUACGCCUGAACAUUGGGGAGUAGCCGGCCUUUGGCAACAAAGGAAUCUGCAUCAACACUCUUGGCACGCAUGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUUGAUCAAGUGACGACCGCAUGGGCCGGGGUCGUUGUUUGGUCUUUGGUUAUUCGUCCGGCCCGAGAAAGUC
................................................................(...)......................................................................(..)...............................................
>AEWG01000141.1/70250-70056
CUAGAAUCGCGCCCGCACUCGUCAUCGGGGAGUAGCCGCCCUGCCGCCCGGCAGGGGUCCGCGCCAACACGCUUGGCCCUCAGGGGCCAUGGUCCGGACAGCCCCCAGCCUGGCAAGACCGCUGACUGCGCCGCCUCCGAAUGGGCCGGGGUCGCGGCGUGGUCAAGCUCCGGUCAUGCCGGCCCGUAUCGGAUU
..............(....)..........................................................(....)...............................................................................................................
>Y14370.1/1315-1188
CAUUUUGUCAGAGGGGAGUAACUUAAGAAUCAUGACCGUAUAAAUGAUUCGACACUUUAUCGUCAUUACGAAGAUAUCUUCCGGUAAAGUGGGCAAUUAAAUUGCUUAGUGAGACCUUUGCUAUUUAU
..............................................................(....)..........................................(..)..............
>CP000103.1/662385-662565
CAAGUAGAAUAUUCCGGUCAUCGGGGAGUAGCUUCCUUCCGUCGAAUAGAAGGGCUUGCAUCAACAUACUUGACCCGUGGUCGUGGUGCAAGGAGUUCGUGCCUGGCAAGACCUUUGACCACAUUGUCUCCGGAAGGGCGGGGAGAAGCCUGGUCUCGCUUCUUGUCCGGCCUGGAGCGUA
................(....)..............................................................(...)............................................................................................
>CP000155.1/3815875-3815690
UUGCAUUAGUAUGCCCGGCGUCACUGGGGAGUAGCCUCUCUUCGCCCUGAAGAGGUUUGCGUCAACAUACUUGGCCCACAGGCCAUGGCGUAAACGGUUCCAUAACUUGGCAAGACCUUUGACUAUGCCGCACCGGUUGGGCCGGGGCGUGGCGUAGUCAUAUGGUUAAUCCGGCCCAGGAGAUUU
...........................................................................(....).......................................................(...).............................................
>CU207211.1/3280200-3280389
CUGCUAUCAUUCGCCCCGAACAUUGGGGAGUAGCCGGCCUUAGUCAACUAAGGGAUCUGCGUCAACAUUCUUGGCCCGCAGGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUCGCUCAAAUGACGACCGCAUGGGCCGGGGUCGCUGUUUGCGCUUUGGUUAUUAUUCCGGCCCCAGAAAGUU
.................(.....)...................................................(....).............................................................................................................
>AF270169.1/2621-2476
AAAACUGUCAGAGGGGAGUAACUUGAGAAUAGUUAUUGAAUGCAUUUAAACCGAUAAUAACUAUUCAACACUUUGUCGUCAUUACGAAGAUAAGUCUUCCGGUAAAGUGGGCAAAAAUAUUGCUAAGUGAGACCUUUGCUAUUAAA
..............................................................................(....)............................................(..)..............
>AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
...................................................................(...).................................................................(.....)..........................................
>FP929140.1/858523-858335
CUGAUAUACUUCGCUGGUCAUUGGGGAGUAGCCGAUCUUCGCACUGAAGAUGCUUACGUCAACACACUUGGCCCACAGGCCAUGGCGUAAGCGGUUCACACGCUUGGCAAGACCUUUGACCACAACGCCUCCGUAUUAAGGCUGGGGAUGCGUCGUGGUCAAUUGUGUCUAAUCCAGCCUGAGAAUCGU
........................................................................(....)...........................................................(..)................................................
>ADGO01015088.1/632-820
CGUGUAUGCUCCCGCCCCGUCAUUGGGGAGUAACCUCCUGCGGCGUUACGCCGCCGGGCUUACAUCAACACACUUGGCCGGUUGGGCCAUGGUGUAAGCGGCUUCAGUGCUUGGUGAGACCUUUGAUCAUGUCGUUCCGGUAUGGGCCGCGGACGGCGUGGUCAAUUGUGUCCUCCGGCCCUGAACGCU
.....................................................................(...).................................................................(......)..........................................
>CP001013.1/98070-98260
UCGCUAUACUCGCGGCGCUUUCGUCAUUGGGGAGUAGCCGCCCUGCGCCCGCAGGGGUUCGCGUCAACACACUUGACCCUCACGGUCAUGGCGCGAACAGCUCCAGAGCCUGGCAAGACCUUUGACCACACUGCCUCCGGAAGGGCCGGGGAUGCCGUGUGGUCUCUGGUAUUCGCUGGCCCUUGGAGAUC
.............................................................................(.....).........................................................(..)..............................................
>CP000270.1/4748060-4747865
CCGUUAGAAUCCCCCGGUCACUGGGGAGUAGCCUUCCUUCAUCGUUUGAAGGAGAACGCGUCAACAUACUUGGCCUUGCAGGUCAUGGCGCGUUCGGCCGUGUCGGUUUGGCGAGACCAUUGACGCACUGCCUCGUUCUGGUCGGACGGGCGGCGGUGCGUCAUUGGUUUGUCGUCUACGUCCGACCGUGGAGUUG
...............................................................(...).....................................................................(.....)....................................................
>ABSP01053999.1/668-852
CCGGUAGAAUCGCGCGGUCAUUGGGGAGUAGUCGCCCUCUACCCAGAGGGGCUUGCGUCAACAUACUUGACCGAUUGGUCAUGGCGCAAGCGGUUUCCUAGCUUGGCGAGACCUUUGACCAUAUCGCCUUCGGACUGGCCGGAGAAGCGGUGUGGUCAUUUGUCUUCUUCCGGCCAGGGAGCACC
............................................................(...)...................................................................(.....)..............................................
>CR555306.1/995584-995774
CCGGUAGAAUUCGCGCCGUCAUCAGGGAGUAGCCGCCUGCGAGCCUUCGCAGGGACCACGUCAACAGACUUGCGCGUCGCGCAUGGCGUGGCCAGCCUUCGGGCCUGGCGAGACUUUUGGCUGCAUGCCCUCCGAUUUUUCGGGCCCGGGAGGCGUGCGGUCAUCGGUCAUCAGCCGGCCCGGAGAACCUG
.................(....)....................................................(...)...............................................................................................................
>AL954747.1/2722783-2722598
CUGUUACAAUUUGCCGGUCAUUGGGGAGUAGCCGCUCUUCGUUUCGAAGGGGCUUACGUCAACAUACUUGACCGGCAGGUCAUGGCGUAAGCGGUUCUAAGCCUGGCAAGACCUUUGACCACAAUGCCUCCGAUUUGGCCGGGGAGGCGUUGUGGUCAAUCGUCUGUAAACCGGCCGGAGAACAUU
.............................................................(...).................................................................(.......)..............................................
3 (.CAY.)
(.NG.)
(().N.)
 14 73.7
>AF270169.1/2621-2476
AAAACUGUCAGAGGGGAGUAACUUGAGAAUAGUUAUUGAAUGCAUUUAAACCGAUAAUAACUAUUCAACACUUUGUCGUCAUUACGAAGAUAAGUCUUCCGGUAAAGUGGGCAAAAAUAUUGCUAAGUGAGACCUUUGCUAUUAAA
..............................................................................(....)..................................((........(..)........).)...
>AEWG01000141.1/70250-70056
CUAGAAUCGCGCCCGCACUCGUCAUCGGGGAGUAGCCGCCCUGCCGCCCGGCAGGGGUCCGCGCCAACACGCUUGGCCCUCAGGGGCCAUGGUCCGGACAGCCCCCAGCCUGGCAAGACCGCUGACUGCGCCGCCUCCGAAUGGGCCGGGGUCGCGGCGUGGUCAAGCUCCGGUCAUGCCGGCCCGUAUCGGAUU
..............(....).........................................................................................((............................(.....).............................).).................
>ABSP01053999.1/668-852
CCGGUAGAAUCGCGCGGUCAUUGGGGAGUAGUCGCCCUCUACCCAGAGGGGCUUGCGUCAACAUACUUGACCGAUUGGUCAUGGCGCAAGCGGUUUCCUAGCUUGGCGAGACCUUUGACCAUAUCGCCUUCGGACUGGCCGGAGAAGCGGUGUGGUCAUUUGUCUUCUUCCGGCCAGGGAGCACC
............................................................(...).............................................................((....(.....)....)..)......................................
>CP001013.1/98070-98260
UCGCUAUACUCGCGGCGCUUUCGUCAUUGGGGAGUAGCCGCCCUGCGCCCGCAGGGGUUCGCGUCAACACACUUGACCCUCACGGUCAUGGCGCGAACAGCUCCAGAGCCUGGCAAGACCUUUGACCACACUGCCUCCGGAAGGGCCGGGGAUGCCGUGUGGUCUCUGGUAUUCGCUGGCCCUUGGAGAUC
.............................................................................(.....)..............................................(.(........(..).........).)..................................
>CP000269.1/3948088-3948277
CUGCUAUCAUUACGCCUGAACAUUGGGGAGUAGCCGGCCUUUGGCAACAAAGGAAUCUGCAUCAACACUCUUGGCACGCAUGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUUGAUCAAGUGACGACCGCAUGGGCCGGGGUCGUUGUUUGGUCUUUGGUUAUUCGUCCGGCCCGAGAAAGUC
................................................................(...)............................................((........................(..).......................)..)....................
>CP000155.1/3815875-3815690
UUGCAUUAGUAUGCCCGGCGUCACUGGGGAGUAGCCUCUCUUCGCCCUGAAGAGGUUUGCGUCAACAUACUUGGCCCACAGGCCAUGGCGUAAACGGUUCCAUAACUUGGCAAGACCUUUGACUAUGCCGCACCGGUUGGGCCGGGGCGUGGCGUAGUCAUAUGGUUAAUCCGGCCCAGGAGAUUU
...........................................................................(....)..............................................((.......(...).......)..)..................................
>CU207211.1/3280200-3280389
CUGCUAUCAUUCGCCCCGAACAUUGGGGAGUAGCCGGCCUUAGUCAACUAAGGGAUCUGCGUCAACAUUCUUGGCCCGCAGGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUCGCUCAAAUGACGACCGCAUGGGCCGGGGUCGCUGUUUGCGCUUUGGUUAUUAUUCCGGCCCCAGAAAGUU
.................(.....).............................................((....(....)...).).......................................................................................................
>AL954747.1/2722783-2722598
CUGUUACAAUUUGCCGGUCAUUGGGGAGUAGCCGCUCUUCGUUUCGAAGGGGCUUACGUCAACAUACUUGACCGGCAGGUCAUGGCGUAAGCGGUUCUAAGCCUGGCAAGACCUUUGACCACAAUGCCUCCGAUUUGGCCGGGGAGGCGUUGUGGUCAAUCGUCUGUAAACCGGCCGGAGAACAUU
.............................................................(...)............................................................((.....(...).....)..).......................................
>CR555306.1/995584-995774
CCGGUAGAAUUCGCGCCGUCAUCAGGGAGUAGCCGCCUGCGAGCCUUCGCAGGGACCACGUCAACAGACUUGCGCGUCGCGCAUGGCGUGGCCAGCCUUCGGGCCUGGCGAGACUUUUGGCUGCAUGCCCUCCGAUUUUUCGGGCCCGGGAGGCGUGCGGUCAUCGGUCAUCAGCCGGCCCGGAGAACCUG
.................(....).....................................................................................(..(.........................(....).........................)....).................
>ADGO01015088.1/632-820
CGUGUAUGCUCCCGCCCCGUCAUUGGGGAGUAACCUCCUGCGGCGUUACGCCGCCGGGCUUACAUCAACACACUUGGCCGGUUGGGCCAUGGUGUAAGCGGCUUCAGUGCUUGGUGAGACCUUUGAUCAUGUCGUUCCGGUAUGGGCCGCGGACGGCGUGGUCAAUUGUGUCCUCCGGCCCUGAACGCU
.....................................................................(...)...............................................((................(......).................).)......................
>CP000555.1/403908-404093
AAUCGCGGCUCCCACCCGUCAUCGGGGAGUAGCCGCCCUGCAUCCGUUGCAGGGGCUCGCGUCAACACACUUGGCCUGCAGGCCAUGGUGCGAGCAGCUUCCACAGCCUGGCAAGACCUUUGACCGCACAGCCUCCGCGUGGCCGGAGAGGCCGUGUGGUCAUUGCGUCAUCCGGCCCAGGACCUC
.................(....).......................................................................................(...(........................(..).........................).)...............
>AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
...................................................................(...)..................................................(.(............(.....).............).)..........................
>FP929140.1/858523-858335
CUGAUAUACUUCGCUGGUCAUUGGGGAGUAGCCGAUCUUCGCACUGAAGAUGCUUACGUCAACACACUUGGCCCACAGGCCAUGGCGUAAGCGGUUCACACGCUUGGCAAGACCUUUGACCACAACGCCUCCGUAUUAAGGCUGGGGAUGCGUCGUGGUCAAUUGUGUCUAAUCCAGCCUGAGAAUCGU
........................................................................(....).................................................(.(.......(..)......).).......................................
>CP000270.1/4748060-4747865
CCGUUAGAAUCCCCCGGUCACUGGGGAGUAGCCUUCCUUCAUCGUUUGAAGGAGAACGCGUCAACAUACUUGGCCUUGCAGGUCAUGGCGCGUUCGGCCGUGUCGGUUUGGCGAGACCAUUGACGCACUGCCUCGUUCUGGUCGGACGGGCGGCGGUGCGUCAUUGGUUUGUCGUCUACGUCCGACCGUGGAGUUG
...............................................................(...)..................................................(.(................(.....)..................).)...............................

>AF270169.1/2621-2476
AAAACUGUCAGAGGGGAGUAACUUGAGAAUAGUUAUUGAAUGCAUUUAAACCGAUAAUAACUAUUCAACACUUUGUCGUCAUUACGAAGAUAAGUCUUCCGGUAAAGUGGGCAAAAAUAUUGCUAAGUGAGACCUUUGCUAUUAAA
..............................................................................(....)..............................................................
..............................................................................(....)............................................(..)..............
..............................................................................(....)..................................((........(..)........).)...
>CU207211.1/3280200-3280389
CUGCUAUCAUUCGCCCCGAACAUUGGGGAGUAGCCGGCCUUAGUCAACUAAGGGAUCUGCGUCAACAUUCUUGGCCCGCAGGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUCGCUCAAAUGACGACCGCAUGGGCCGGGGUCGCUGUUUGCGCUUUGGUUAUUAUUCCGGCCCCAGAAAGUU
.................(.....)......................................................................................................................................................................
.................(.....)...................................................(....).............................................................................................................
.................(.....).............................................((....(....)...).).......................................................................................................
>CR555306.1/995584-995774
CCGGUAGAAUUCGCGCCGUCAUCAGGGAGUAGCCGCCUGCGAGCCUUCGCAGGGACCACGUCAACAGACUUGCGCGUCGCGCAUGGCGUGGCCAGCCUUCGGGCCUGGCGAGACUUUUGGCUGCAUGCCCUCCGAUUUUUCGGGCCCGGGAGGCGUGCGGUCAUCGGUCAUCAGCCGGCCCGGAGAACCUG
.................(....)........................................................................................................................................................................
.................(....)....................................................(...)...............................................................................................................
.................(....).....................................................................................(..(.........................(....).........................)....).................
>AL954747.1/2722783-2722598
CUGUUACAAUUUGCCGGUCAUUGGGGAGUAGCCGCUCUUCGUUUCGAAGGGGCUUACGUCAACAUACUUGACCGGCAGGUCAUGGCGUAAGCGGUUCUAAGCCUGGCAAGACCUUUGACCACAAUGCCUCCGAUUUGGCCGGGGAGGCGUUGUGGUCAAUCGUCUGUAAACCGGCCGGAGAACAUU
.............................................................(...)........................................................................................................................
.............................................................(...).................................................................(.......)..............................................
.............................................................(...)............................................................((.....(...).....)..).......................................
>CP000155.1/3815875-3815690
UUGCAUUAGUAUGCCCGGCGUCACUGGGGAGUAGCCUCUCUUCGCCCUGAAGAGGUUUGCGUCAACAUACUUGGCCCACAGGCCAUGGCGUAAACGGUUCCAUAACUUGGCAAGACCUUUGACUAUGCCGCACCGGUUGGGCCGGGGCGUGGCGUAGUCAUAUGGUUAAUCCGGCCCAGGAGAUUU
...........................................................................(....).........................................................................................................
...........................................................................(....).......................................................(...).............................................
...........................................................................(....)..............................................((.......(...).......)..)..................................
>CP000555.1/403908-404093
AAUCGCGGCUCCCACCCGUCAUCGGGGAGUAGCCGCCCUGCAUCCGUUGCAGGGGCUCGCGUCAACACACUUGGCCUGCAGGCCAUGGUGCGAGCAGCUUCCACAGCCUGGCAAGACCUUUGACCGCACAGCCUCCGCGUGGCCGGAGAGGCCGUGUGGUCAUUGCGUCAUCCGGCCCAGGACCUC
.................(....)...................................................................................................................................................................
.................(....)....................................................(....).........................................................................................................
.................(....).......................................................................................(...(........................(..).........................).)...............
>ADGO01015088.1/632-820
CGUGUAUGCUCCCGCCCCGUCAUUGGGGAGUAACCUCCUGCGGCGUUACGCCGCCGGGCUUACAUCAACACACUUGGCCGGUUGGGCCAUGGUGUAAGCGGCUUCAGUGCUUGGUGAGACCUUUGAUCAUGUCGUUCCGGUAUGGGCCGCGGACGGCGUGGUCAAUUGUGUCCUCCGGCCCUGAACGCU
.....................................................................(...)...................................................................................................................
.....................................................................(...).................................................................(......)..........................................
.....................................................................(...)...............................................((................(......).................).)......................
>FP929140.1/858523-858335
CUGAUAUACUUCGCUGGUCAUUGGGGAGUAGCCGAUCUUCGCACUGAAGAUGCUUACGUCAACACACUUGGCCCACAGGCCAUGGCGUAAGCGGUUCACACGCUUGGCAAGACCUUUGACCACAACGCCUCCGUAUUAAGGCUGGGGAUGCGUCGUGGUCAAUUGUGUCUAAUCCAGCCUGAGAAUCGU
........................................................................(....)...............................................................................................................
........................................................................(....)...........................................................(..)................................................
........................................................................(....).................................................(.(.......(..)......).).......................................
>AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
...................................................................(...)..................................................................................................................
...................................................................(...).................................................................(.....)..........................................
...................................................................(...)..................................................(.(............(.....).............).)..........................
>CP000269.1/3948088-3948277
CUGCUAUCAUUACGCCUGAACAUUGGGGAGUAGCCGGCCUUUGGCAACAAAGGAAUCUGCAUCAACACUCUUGGCACGCAUGCCAUGGUGCAGAUAGUCGCAAGACUUGGCGAGACCAUUGAUCAAGUGACGACCGCAUGGGCCGGGGUCGUUGUUUGGUCUUUGGUUAUUCGUCCGGCCCGAGAAAGUC
................................................................(...).........................................................................................................................
................................................................(...)......................................................................(..)...............................................
................................................................(...)............................................((........................(..).......................)..)....................
>CP001013.1/98070-98260
UCGCUAUACUCGCGGCGCUUUCGUCAUUGGGGAGUAGCCGCCCUGCGCCCGCAGGGGUUCGCGUCAACACACUUGACCCUCACGGUCAUGGCGCGAACAGCUCCAGAGCCUGGCAAGACCUUUGACCACACUGCCUCCGGAAGGGCCGGGGAUGCCGUGUGGUCUCUGGUAUUCGCUGGCCCUUGGAGAUC
.............................................................................(.....)...........................................................................................................
.............................................................................(.....).........................................................(..)..............................................
.............................................................................(.....)..............................................(.(........(..).........).)..................................
>CP000270.1/4748060-4747865
CCGUUAGAAUCCCCCGGUCACUGGGGAGUAGCCUUCCUUCAUCGUUUGAAGGAGAACGCGUCAACAUACUUGGCCUUGCAGGUCAUGGCGCGUUCGGCCGUGUCGGUUUGGCGAGACCAUUGACGCACUGCCUCGUUCUGGUCGGACGGGCGGCGGUGCGUCAUUGGUUUGUCGUCUACGUCCGACCGUGGAGUUG
...............................................................(...)................................................................................................................................
...............................................................(...).....................................................................(.....)....................................................
...............................................................(...)..................................................(.(................(.....)..................).)...............................
>ABSP01053999.1/668-852
CCGGUAGAAUCGCGCGGUCAUUGGGGAGUAGUCGCCCUCUACCCAGAGGGGCUUGCGUCAACAUACUUGACCGAUUGGUCAUGGCGCAAGCGGUUUCCUAGCUUGGCGAGACCUUUGACCAUAUCGCCUUCGGACUGGCCGGAGAAGCGGUGUGGUCAUUUGUCUUCUUCCGGCCAGGGAGCACC
............................................................(...)........................................................................................................................
............................................................(...)...................................................................(.....)..............................................
............................................................(...).............................................................((....(.....)....)..)......................................
>AEWG01000141.1/70250-70056
CUAGAAUCGCGCCCGCACUCGUCAUCGGGGAGUAGCCGCCCUGCCGCCCGGCAGGGGUCCGCGCCAACACGCUUGGCCCUCAGGGGCCAUGGUCCGGACAGCCCCCAGCCUGGCAAGACCGCUGACUGCGCCGCCUCCGAAUGGGCCGGGGUCGCGGCGUGGUCAAGCUCCGGUCAUGCCGGCCCGUAUCGGAUU
..............(....)...............................................................................................................................................................................
..............(....)..........................................................(....)...............................................................................................................
..............(....).........................................................................................((............................(.....).............................).).................
>Y14370.1/1315-1188
CAUUUUGUCAGAGGGGAGUAACUUAAGAAUCAUGACCGUAUAAAUGAUUCGACACUUUAUCGUCAUUACGAAGAUAUCUUCCGGUAAAGUGGGCAAUUAAAUUGCUUAGUGAGACCUUUGCUAUUUAU
..............................................................(....)............................................................
..............................................................(....)..........................................(..)..............
>CP000103.1/662385-662565
CAAGUAGAAUAUUCCGGUCAUCGGGGAGUAGCUUCCUUCCGUCGAAUAGAAGGGCUUGCAUCAACAUACUUGACCCGUGGUCGUGGUGCAAGGAGUUCGUGCCUGGCAAGACCUUUGACCACAUUGUCUCCGGAAGGGCGGGGAGAAGCCUGGUCUCGCUUCUUGUCCGGCCUGGAGCGUA
................(....)...............................................................................................................................................................
................(....)..............................................................(...)............................................................................................
>CP001052.1/4299894-4299707
CCGUUAAAAUCCCCCGGUCACUGGGGAGUAGCCUUCCUUCAUCCAUUGAAGGAGAGCGCGUCAACAUACUUGGCCUGCGGGUCAUGGCGCGUUCGACCGGGUCGGUUUGGCGAGACCAUUGACGCACUGCCUCGUUCUGGUCGGACGGGCGGCGGUGCGUCAUUGGUUUGUUAUCGACGUCCGACCGC
........................................(.....).............................................................................................................................................
>AEGR01000046.1/5080-4892
UUGUUAGAAUGCGCCCCGUCAUUGGGGAGUAGCCGCUCUUCACCGCGAAGAGGCUUGCGUCAACACACUUGGUCCAUCGGACCAUGGCGCAGGCAGCUCCUGGCCUGGCAAGACCUUUGACCACGAAGCCUCCGUUUUGGCCGGGGAUGCGUCGUGGUCAAUCGUCUCUGUACACCGGCCUUGGACAUU
.................(....)......................................................................................................................................................................

ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio
1 (.CAY.) < 0.001 2.14
AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
...................................................................................................1......................................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.........7.........8......
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2 (.NG.) < 0.001 1.11
AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
...................................................................................................1......................................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.........7.........8......
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3 (().N.) 0.00133 1.06
AM406670.1/393403-393588
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
UCGCUAAUAUCCGCGCCUUCAUUGGGGAGUAGCCGCCCUUCACCGUGGUGAAGGGGCUUGCGUCAACACACUUGGCCGUCCGGCCAUGGCGCAAGCAGUUCCUGGACUUGGCAAGACCUUUGAUCACGAUGCCUCUGGUAUGGCCGGGGAGGCGCGUGGUCAUCGGUUGUACCGGCCAGGGAUCAU
...................................................................................................1......................................................................................
.........1.........2.........3.........4.........5.........6.........7.........8.........9.........0.........1.........2.........3.........4.........5.........6.........7.........8......
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ORB p-value ORB frequency
(per structure per nucleotide) 		Means
ratio

NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio
1 (.AYU.()) < 0.001 10.1
2 (NY()RN) (URB) < 0.001 0
NCM p-value NCM frequency
(per structure per nucleotide) 		Means
ratio

Structure is visualized using R2R 1.0.6 (Zasha Weinberg).
LOGOS are generated with ggseqlogo (Omar Wagih).