| If you have: | And want to: | You can: |
|---|---|---|
| A set of sequences sharing a common function |
-Identify distinctive ORBs
-Generate classifiers -Generate a consensus structure |
Use the Create tool |
| Two sets of sequences, positives and negatives, where the positives share a common function lacking in the negatives |
-Identify discriminant ORBs
-Generate classifiers -Generate a consensus structure |
Use the Create tool, and check the "Submit negative sequences" option to incude the set of negatives |
| One or more sequence(s) | -Predict the Rfam-derived families of these sequences | Use the Query tool to run the sequence(s) through our Rfam-derived classifers |
| A wildtype sequence | -Generate muted variants | Use the Mutate tool |
| The need | -To get the picture of a specific NCM | Use the Draw tool |
| Curiosity | -Browse our Rfam-derived families | Browse our Rfam-derived families using the gray button on top right |
| One or more sequence(s) | -Categorize each sequence with resulting classifiers | Use the "Categorize" button on a result page |
| One or more sequence(s) | -Generate secondary structures for each sequence, matching either a D-ORB structure or ORBs | Use the "Fold" button on a result page |
| A wildtype sequence | -Identify mutants that lose important ORBs | Use the "Mutagenize" button on a result page |